Scopus
YÖKSİS DOI Eşleşti
SJR Q3
Hypoglycemic, antioxidant, antimicrobial activities and phytochemical analyses of Rhaponticoides iconiensis leafy stem extracts
Vegetos · Eylül 2021
YÖKSİS Kayıtları
Hypoglycemic, antioxidant, antimicrobial activities and phytochemical analyses of Rhaponticoides iconiensis leafy stem extracts
Vegetos · 2021 SCOPUS
Prof. Dr. OSMAN TUGAY →
Hypoglycemic, antioxidant, antimicrobial activities and phytochemical analyses of Rhaponticoides iconiensis leafy stem extracts
Vegetos · 2021 SCOPUS
Dr. Öğr. Üyesi CENGİZHAN CEYLAN →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Correlation Between Traits and Path Analysis For Seed Yield in Cephalaria syriaca Lines
2013 ISSN: 0970-4078 SCI-Expanded
Prof. Dr. RAHİM ADA →
Hypoglycemic, antioxidant, antimicrobial activities and phytochemical analyses of Rhaponticoides iconiensis leafy stem extracts
2021 ISSN: 09704078 SCOPUS
Prof. Dr. OSMAN TUGAY →
Makale Bilgileri
Dergi
Vegetos
ISSN09704078
Yayın TarihiEylül 2021
Cilt / Sayfa34 · 592-599
Scopus ID2-s2.0-85113407764
Özet
Rhaponticoides iconiensis (Hub.-Mor.) M.V.Agab. & Greuter is one of the species of Asteraceae family. In this study, the α-amylase and α-glucosidase inhibition activity, the antioxidant, antimicrobial properties and the phytochemical composition of extract and sub-extracts from the leafy stem of R. iconiensis were evaluated. The antimicrobial effect of extracts was tested with the microdilution method and the antioxidant activity was investigated with DPPH·, ABTS·+ and FRAP tests. The phytochemical composition of active sub-extract carried out by LC–MS/MS. As a result, the highest α-glucosidase and α-amylase activity were found in ethyl acetate sub-extract (TSE) of R. iconiensis leafy stem extract (IC50 = 12.108 ± 0.582 µg/mL and 287.733 ± 0.325 µg/mL, respectively). Moreover, the highest total phenolic (312.001 ± 2.008 mgGAE/gextract) and total flavonoid content (242.007 ± 2.646 mgCA/gextract) was found in TSE extract too and this extract was found more active on DPPH· (IC50 = 0.249 ± 0.002 mg/mL), ABTS+· (at a concentration of 0.5 mg/mL equivalent to 0.542 ± 0.002 µM Trolox) and FRAP (at a concentration of 1 mg/mL equivalent to 3642.005 ± 2.646 mmol Fe2+) tests. Besides that, the flavonoids such as apigenin, naringin and patuletin derivatives were determined as the main compounds of active TSE sub-extract. This is the first report that these biological activities investigated and phytochemical compounds were identified in leafy stem extracts of R. iconiensis and it is thought that these studies will be shed light on future studies on this species.
Yazarlar (5)
1
Leyla Paşayeva
ORCID: 0000-0003-3860-7222
2
Ufuk İnce
3
Hanifa Fatullayev
4
Cengizhan Ceylan
ORCID: 0000-0003-4164-9212
5
Osman Tugay
Anahtar Kelimeler
Antimicrobial activity
Diabet
LC–MS/MS
α-Amylase
α-Glucosidase
Kurumlar
Erciyes Üniversitesi
Kayseri Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Vegetos
Q3
SJR Skoru0,247
H-Index24
YayıncıSpringer
ÜlkeSingapore
Plant Science (Q3)
Metrikler
7
Atıf
5
Yazar
5
Anahtar Kelime