Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Behaviours of drugs in the milk - A review
Ataturk Universitesi Veteriner Bilimleri Dergisi · Ocak 2018
YÖKSİS Kayıtları
İlaçların Sütteki Davranışları - Derleme
Atatürk Üniversitesi Veteriner Bilimleri Dergisi · 2018 Art Index (Art Research Database, EBSCO)
PROFESÖR BÜNYAMİN TRAŞ →
Makale Bilgileri
DergiAtaturk Universitesi Veteriner Bilimleri Dergisi
Yayın TarihiOcak 2018
Cilt / Sayfa13 · 364-372
Scopus ID2-s2.0-85059901538
Erişim🔓 Açık Erişim
Özet
Milk is a food containing many biologically active substances that have an important place in the nourishment of newborns and adults. The transition of the drugs used in the treatment, as well as the environmental pollutants to milk cause a potential risk for consumer health as well as economical losses due to exceed of the legal limits of these compounds set by authorities. The transition of these chemicals to milk is complex; while active transport and passive diffusion play were found to have an important role. The transition abilities of the drugs into milk are defined by milk/plasma ratio. The M/P ratios of the drugs are affected by the composition of the milk and the physicochemical properties of the drug. The concentration of the drugs in the milk depends on the factors of the drug (protein binding, ionization, molecular weight, lipophilicity, drug-drug and drug-nutrient interactions) and organism (race, species, lactation period, parity, disease and nutrition). If the transition properties of the compounds of concern are known or able to be modelized in kinetic applications, it can be useful for preventing milk from drug residues.The success of mastitis treatment depends on the proper use of drugs and knowing of the behaviour of drugs in the milk.
Yazarlar (2)
1
Zeynep Ozdemir Kutahya
2
B. Traş
Anahtar Kelimeler
Behaviour
Drug
Factor
Milk
Transition
Kurumlar
Anatolia Medicine & Chemical Industry Corporation
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
1
Atıf
2
Yazar
5
Anahtar Kelime