Scopus
YÖKSİS DOI Eşleşti
SJR Q2
Evaluation of the clinical efficacy of racecadotril in the treatment of neonatal calves with infectious diarrhea
Polish Journal of Veterinary Sciences · Ocak 2023
YÖKSİS Kayıtları
Evaluation of the clinical efficacy of racecadotril in the treatment of neonatal calves with infectious diarrhea
Polish journal of veterinary sciences · 2023 SCI-Expanded
Doç. Dr. MERVE İDER →
Evaluation of the clinical efficacy of racecadotril in the treatment of neonatal calves with infectious diarrhea
Polish journal of veterinary sciences · 2023 SCI-Expanded
Prof. Dr. KAMİL ÜNEY →
Evaluation of the clinical efficacy of racecadotril in the treatment of neonatal calves with infectious diarrhea
Polish Academy of Sciences Chancellery · 2023 SCI-Expanded
Prof. Dr. MAHMUT OK →
Evaluation of the clinical efficacy of racecadotril in the treatment of neonatal calves with infectious diarrhea
Polish journal of veterinary sciences · 2023 SCI-Expanded
Prof. Dr. BÜNYAMİN TRAŞ →
Evaluation of the clinical efficacy of racecadotril in the treatment of neonatal calves with infectious diarrhea
Polish Journal of Veterinary Science · 2023 SCI-Expanded
Dr. Öğr. Üyesi TUĞBA MELİKE PARLAK →
Evaluation of the clinical efficacy of racecadotril in the treatment of neonatal calves with infectious diarrhea
Polish journal of veterinary sciences · 2023 SCI-Expanded
Prof. Dr. MAHMUT OK →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Effect of combinations of intravenous small-volume hypertonic sodium chloride, acetate Ringer, sodium bicarbonate, and lactate Ringer solutions along with oral fluid on the treatment of calf diarrhea
2018 ISSN: 1505-1773 SCI-Expanded Q3
Doç. Dr. AMİR NASERİ →
Effect of combinations of intravenous small-volume hypertonic sodium chloride, acetate Ringer, sodium bicarbonate, and lactate Ringer solutions along with oral fluid on the treatment of calf diarrhea
2018 ISSN: 1505-1773 SCI
Prof. Dr. HASAN GÜZELBEKTEŞ →
The level of serum ionised calcium, aspartate aminotransferase, insulin, glucose, betahydroxybutyrate concentrations and blood gas parameters in cows with left displacement of abomasum
2006 ISSN: 1505-1773 SCI-Expanded
Prof. Dr. MAHMUT OK →
The evaluation of hemostatic dysfunction and disseminated intravascular coagulation in dairy cows with abomasal displacement
2018 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. MUSTAFA ARICAN →
The evaluation of hemostatic dysfunction and disseminated intravascular coagulation in dairy cows with abomasal displacement
2018 ISSN: 1505-1773 SCI-Expanded
Prof. Dr. RAMAZAN ÇÖL →
Glucose-6-phosphate dehydrogenase,glutathione peroxidase, total glutationeand reduced nicotinamide adeninedinucleotide phosphate in milk cellsof subclinical mastitic cows
2018 ISSN: 1505-1773 SCI-Expanded
Prof. Dr. NURİ BAŞPINAR →
Assessment of intestinal and cardiac-related biomarkers in dogs with parvoviral enteritis
2020 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. MAHMUT OK →
Assessment of intestinal and cardiac-related biomarkers in dogs with parvoviral enteritis
2020 ISSN: 1505-1773 SCI-Expanded Q3
Doç. Dr. MERVE İDER →
The clinical efficacy of pentoxifylline and l-glutamine on ischemia and reperfusion injury in cattle with displaced abomasum: a longitudinal study
2021 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. MEHMET MADEN →
The clinical efficacy of pentoxifylline
and l-glutamine on ischemia and reperfusion
injury in cattle with displaced abomasum:
a longitudinal study
2021 ISSN: 1505-1773 SCI-Expanded Q3
Doç. Dr. KURTULUŞ PARLAK →
The clinical efficacy of pentoxifylline and l-glutamine on ischemia and reperfusion injury in cattle with displaced abomasum: a longitudinal study
2021 ISSN: 1505-1773 SCI-Expanded
Prof. Dr. MUSTAFA ARICAN →
The clinical efficacy of pentoxifylline and l-glutamine on ischemia and reperfusion injury in cattle with displaced abomasum: a longitudinal study
2021 ISSN: 1505-1773 SCI-Expanded Q2
Prof. Dr. BÜNYAMİN TRAŞ →
The clinical efficacy of pentoxifylline and l-glutamine on ischemia and reperfusion injury in cattle with displaced abomasum: a longitudinal study
2021 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. RAMAZAN ÇÖL →
The effects of dexamethasone and minocycline alone and combined with N-acetylcysteine and vitamin E on serum matrix metalloproteinase-9 and coenzyme Q10 levels in aflatoxin B1 administered rats
2022 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. KAMİL ÜNEY →
The effects of dexamethasone and minocycline alone and combined with N-acetylcysteine and vitamin E on serum matrix metalloproteinase-9 and coenzyme Q10 levels in aflatoxin B1 administered rats
2022 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. BURAK DİK →
Molecular cloning of the OMP19 gene from Brucella melitensis strain H38 and its antigenicity compared to that of commercial OMP19
2022 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. ZAFER SAYIN →
Molecular cloning of the OMP19 gene from Brucella melitensis strain H38 and its antigenicity compared to that of commercial OMP19
2022 ISSN: 1505-1773 SCI-Expanded Q3
Prof. Dr. OSMAN ERGANİŞ →
The effects of dexamethasone and minocycline alone and combined with N-acetylcysteine and vitamin E on serum matrix metalloproteinase-9 and coenzyme Q10 levels in aflatoxin B1 administered rats
2022 ISSN: 15051773 SCI Q3
Prof. Dr. BÜNYAMİN TRAŞ →
Molecular cloning of the OMP19 gene from Brucella melitensis strain H38 and its antigenicity compared to that of commercial OMP19
2022 ISSN: 1505-1773 SCI-Expanded Q3
Doç. Dr. ALİ USLU →
The effect of tilmicosin and diclofenac sodium combination on cardiac biomarkers in sheep
2023 ISSN: 1505-1773 SCI-Expanded Q3
Doç. Dr. MERVE İDER →
Makale Bilgileri
ISSN15051773
Yayın TarihiOcak 2023
Cilt / Sayfa26 · 559-569
Scopus ID2-s2.0-85179645315
Özet
Racecadotril, used as an antidiarrheal drug in humans and some animals such as the dog, inhibits peripheral enkephalinase, which degrades enkephalins and enkephalinase inhibition induces a selective increase in chloride absorption from the intestines. The study material consisted of 46 calves with infectious diarrhea and 14 healthy calves in the age 2-20 days. The calves were divided into eight groups; healthy calves (HG), healthy calves administered racecadotril (HRG), calves with E.coli-associated diarrhea (ECG), calves with E.coli-associated diarrhea administered racecadotril (ECRG), calves with bovine Rotavirus/Coronavirus-associated diarrhea (VG), calves with bovine Rotavirus/Coronavirus-associated diarrhea administered racecadotril (VRG), calves with C. parvum-associated diarrhea (CG) and calves with C. parvum-associated diarrhea administered racecadotril (CRG). Calves in the racecadotril groups received oral racecadotril at a dose of 2.5 mg/kg twice a day for 3 days. A routine clinical examination of all calves was performed. Hemogram and blood gas measurements were made from the blood samples. Standard diarrhea treatment was applied to the HG, ECG, CG, and VG groups. Clinical score parameters such as appetite, feces quality, dehydration, standing and death and some blood gas and hemogram parameters were evaluated to determine the clinical efficacy of racecadotril. Clinical score parameters were determined observationally. Blood gas measurements were performed using a blood gas analyzer. The hemogram was performed using an automated hematologic analyzer. Statistically significant differences were determined in the blood pH, bicarbonate, base deficit, lactate, and total leukocyte count in calves with diarrhea compared to healthy calves. After the treatments, these parameters were found to be within normal limits. At the end of treatment, 42 of the 46 diarrheal calves recovered, while 4 died. We found that racecadotril was effective in improving both clinical recovery and feces consistency in neonatal calves with diarrhea caused by E. coli. As a result, it can be stated that racecadotril, which has an antisecretory effect, is beneficial in the treatment of bacterial diarrhea caused by such as E. coli.
Yazarlar (8)
1
B. Traş
2
M. Ok
3
Merve Ider
ORCID: 0000-0003-2928-5452
4
T. M. Parlak
5
Ramazan Yildiz
6
Hatice Eser Faki
7
Zeynep Ozdemir Kutahya
8
Kamil Üney
ORCID: 0000-0002-8674-4873
Anahtar Kelimeler
infectious diarrhea
neonatal calf
racecadotril
treatment
Kurumlar
Burdur Mehmet Akif Ersoy Üniversitesi
Burdur Turkey
Çukurova Üniversitesi
Adana Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Polish Journal of Veterinary Sciences
Q2
SJR Skoru0,348
H-Index39
YayıncıPolska Akademia Nauk
ÜlkePoland
Veterinary (miscellaneous) (Q2)
Medicine (miscellaneous) (Q3)
Metrikler
1
Atıf
8
Yazar
4
Anahtar Kelime