Scopus
YÖKSİS DOI Eşleşti
SJR Q4
Effect of gabapentin on postoperative pain: A randomized, placebo-controlled clinical study
Pain Clinic · Nisan 2005
YÖKSİS Kayıtları
Effect of Gabapentin on Postoperative pain: A Randomized, placebo-controlled clinical study
The Pain Clinic · 2005 Endekste taranmıyor
Prof. Dr. FARUK ÇİÇEKCİ →
YÖKSİS Kayıtları — ISSN Eşleşmesi
The effects of adding diphenhydramine hydrochloride to lidocaine in intravenous regional anaesthesia
2003 ISSN: 0169-1112 SCI-Expanded
Prof. Dr. JALE BENGİ ÇELİK →
Makale Bilgileri
Dergi
Pain Clinic
ISSN01691112
Yayın TarihiNisan 2005
Cilt / Sayfa17 · 95-99
Scopus ID2-s2.0-17144418092
Özet
Background: Both clinical and experimental studies suggest that gabapentin (GBP) has analgesic effects in neuropathic pain. The aim of the study was to investigate the effect of gabapentin on postoperative pain. Methods: This study was performed on 45 (ASA I-II) patients planned for major orthopaedic surgery. 45 patients were randomized into three equal groups. Patients received 1200 mg GBP (Group I), 800 mg GBP (Group II) or placebo (Group III) 1 h before surgery. Anaesthesia was standardized for all patients. Morphine by intravenous patient-controlled analgesia was applied as 1 mg bolus dose and 7 min lockout time for postoperative analgesia. The pain was evaluated at the first 2 and 4 h after operation. The amount of morphine used was recorded at the same hours. Results: In all groups, there were no significant differences in the demographic characteristics, duration of surgery and anaesthesia, or dose of fentanyl received in the operating room. Pain scores and side effects were similar in all groups. Morphine consumption was lower in the Groups I and II than in the Group III at 2 h and 4 h postoperatively (p < 0.05). Morphine consumption was lower in the Group I than in the Group II at 2 h and 4 h (p < 0.05). Conclusion: Our results demonstrate that a single dose of 1200 or 800 mg oral gabapentin reduces morphine consumption in the early postoperative period. However, gabapentin 1200 mg is more effective than gabapentin 800 mg for pre-emptive analgesic effect. © 2005 VSP.
Yazarlar (6)
1
Sema Tuncer
2
Hulagu Bariskaner
ORCID: 0000-0001-6600-4635
3
Ruhiye Reisli
4
Gamze Sarkilar
5
Faruk Cicekci
6
Şeref Otelcioǧlu
Anahtar Kelimeler
Gabapentin
Placebo
Postoperative pain
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Pain Clinic
Q4
SJR Skoru0,106
H-Index21
YayıncıManey Publishing
ÜlkeUnited Kingdom
Anesthesiology and Pain Medicine (Q4)
Neurology (clinical) (Q4)
Metrikler
18
Atıf
6
Yazar
3
Anahtar Kelime