Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q3
Are owned dogs or stray dogs more prepared to diseases? A comparative study of immune system gene expression of perforin and granzymes
Acta Veterinaria Hungarica · Mart 2022
YÖKSİS Kayıtları
Are owned dogs or stray dogs more prepared to diseases? A comparative study of immune system gene expression of perforin and granzymes
Akademiai Kiado Zrt. · 2022 SCI-Expanded
Dr. Öğr. Üyesi GONCA SÖNMEZ →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Zinc supplementation decreases total thyroid hormone concentration in small ruminants
2002 ISSN: 0236-6290 SCI 18 atıf
Prof. Dr. TUFAN KEÇECİ →
Effects of bovine viral diarrhoea virus on the fertility of cows
2013 ISSN: 0236-6290 SSCI
Prof. Dr. SİBEL YAVRU →
ASSESSMENT OF THE CARDIOTOXICITY OF TULATHROMYCIN IN RABBITS
2011 ISSN: 0236-6290 SCI-Expanded 37 atıf
Prof. Dr. MUAMMER ELMAS →
EFFECTS OF ENROFLOXACIN FLUNIXIN MEGLUMINE AND DEXAMETHASONE ONDISSEMINATED INTRAVASCULAR COAGULATION CYTOKINE LEVELS AND ADENOSINEDEAMINASE ACTIVITY IN ENDOTOXAEMIA IN RATS
2010 ISSN: 0236-6290 SCI-Expanded 23 atıf
Prof. Dr. MUAMMER ELMAS →
EFFECTS OF TYLOSIN ON SERUM CYTOKINE LEVELS IN HEALTHY ANDLIPOPOLYSACCHARIDE TREATED MICE
2010 ISSN: 0236-6290 SCI-Expanded 18 atıf
Prof. Dr. MUAMMER ELMAS →
Zinc Supplementation Decreases Total Thyroid Hormone Concentration in Small Ruminants
2002 ISSN: 0236-6290 SCI-Expanded
Prof. Dr. ERCAN KESKİN →
Cardiac biomarkers in premature calves with respiratory distress syndrome
2016 ISSN: 0236-6290 SCI
Prof. Dr. HASAN GÜZELBEKTEŞ →
Effects of bovine viral diarrhoea virus on the fertility of cows
2013 ISSN: 0236-6290 SCI-Expanded
Prof. Dr. ORHAN YAPICI →
Effect of pentoxifylline on endotoxin induced haemostatic disturbances in rabbits
2005 ISSN: 0236-6290 SCI 7 atıf
Prof. Dr. RAMAZAN ÇÖL →
Effect of recombinant interleukin 10 on some haematological and biochemical parameters in a rat endotoxaemic model
2011 ISSN: 0236-6290 SCI 6 atıf
Prof. Dr. RAMAZAN ÇÖL →
Effects of Arginine and Trehalose on Post-thawed Bovine Sperm Quality
2017 ISSN: 0236-6290 SCI
Prof. Dr. MUSTAFA NUMAN BUCAK →
Effects of arginine and trehalose on post-thawed bovine sperm quality
2017 ISSN: 0236-6290 SCI
Prof. Dr. NURİ BAŞPINAR →
Plasma disposition of cefoperazone after single intravenous and intramuscular administrations in camels (Camelus dromedarius) )/title
2018 ISSN: 0236-6290 SCI-Expanded
Prof. Dr. MUAMMER ELMAS →
title Plasma disposition of cefoperazone after single intravenous and intramuscular administrations in camels ( iCamelus dromedarius/i )/title
2018 ISSN: 0236-6290 SCI-Expanded
Prof. Dr. KAMİL ÜNEY →
Assessment of the cardiotoxicity of tulathromycin in rabbits
2011 ISSN: 0236-6290 SSCI
Prof. Dr. ENVER YAZAR →
Effect of pentoxifylline on endotoxin-induced haemostatic, disturbances in rabbits
2005 ISSN: 0236-6290 SCI-Expanded
Prof. Dr. ERCAN KESKİN →
Changes In Novel Gastrointestinal And Renal Injury Markers In The Blood Plasma Of Sheep Following Increasing Intravenous Doses Of Tolfenamic Acid
2019 ISSN: 0236-6290 SCI
Prof. Dr. MAHMUT OK →
Heart-type fatty acid-binding protein (H-FABP), pentraxin-3 (PTX-3) and thrombomodulin in bovine traumatic pericarditis
2019 ISSN: 0236-6290 SCI-Expanded Q3
Doç. Dr. MERVE İDER →
CHANGES IN NOVEL GASTROINTESTINAL AND RENAL INJURY MARKERS IN THE BLOOD PLASMA OF SHEEP FOLLOWING INCREASING INTRAVENOUS DOSES OF TOLFENAMIC ACID
2019 ISSN: 0236-6290 SCI
Prof. Dr. KAMİL ÜNEY →
Effects of tylosin, tilmicosin and tulathromycin on inflammatory mediators in bronchoalveolar lavage fluid of lipopolysaccharide-induced lung injury
2012 ISSN: 0236-6290 SCI-Expanded
Prof. Dr. ENVER YAZAR →
Makale Bilgileri
ISSN02366290
Yayın TarihiMart 2022
Cilt / Sayfa70 · 24-29
Scopus ID2-s2.0-85127251522
Erişim🔓 Açık Erişim
Özet
Stray dogs are inevitably exposed to more infections than owned dogs living indoor. However, no studies have investigated whether the immune system gene expression differs between owned dogs kept in better care conditions and stray dogs living outside. To investigate this, blood samples were taken from 90 dogs (45 owned and 45 stray dogs) that were checked and confirmed as healthy. By using qPCR, the amples were analyzed for the expression of the perforin, granzyme A and granzyme B genes, which are associated with the activation of apoptotic pathways in the immune system. We found that the perforin and granzyme A gene expression levels were higher in stray dogs although the differences were not statistically significant. On the other hand, a 2.81 times higher and a notable difference (P < 0.001) was found in the expression level of granzyme B gene in stray dogs. These results indicate that the immune system in stray dogs might be more prepared for diseases than that of the owned dogs and the granzyme B gene plays a more dominant role in the immune response than granzyme A and perforin.
Yazarlar (2)
1
Mehmet Cevat Temizkan
2
Gonca Sönmez
Anahtar Kelimeler
canine
gene expression
granzyme
owned dog
perforin
stray dog
Kurumlar
Bozok Üniversitesi
Yozgat Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Acta Veterinaria Hungarica
Q3
SJR Skoru0,281
H-Index42
YayıncıAkademiai Kiado ZRt.
ÜlkeHungary
Veterinary (miscellaneous) (Q3)
Metrikler
8
Atıf
2
Yazar
6
Anahtar Kelime