Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Fatty Acid Composition, Antioxidant, and Enzyme Inhibition Activities of Cachrys crassiloba (Boiss.) Meikle Fruit and Leaf Extracts
Journal of the Turkish Chemical Society, Section A: Chemistry · Ocak 2024
YÖKSİS Kayıtları
Fatty Acid Composition, Antioxidant, and Enzyme Inhibition Activities of Cachrys Crassiloba (Boiss.) Meikle Fruit and Leaf Extracts
Journal of the Turkish Chemical Society Section A: Chemistry · 2024 TR DİZİN
PROFESÖR YAVUZ BAĞCI →
Fatty Acid Composition, Antioxidant, and Enzyme Inhibition Activities of Cachrys Crassiloba (Boiss.) Meikle Fruit and Leaf Extracts
Journal of the Turkish Chemical Society Section A: Chemistry · 2024 SCOPUS
PROFESÖR YAVUZ BAĞCI →
Fatty Acid Composition, Antioxidant, and Enzyme Inhibition Activities of Cachrys Crassiloba (Boiss.) Meikle Fruit and Leaf Extracts
Journal of the Turkish Chemical Society Section A: Chemistry · 2024 TR DİZİN
PROFESÖR YAVUZ BAĞCI →
Fatty Acid Composition, Antioxidant, and Enzyme Inhibition Activities of Cachrys Crassiloba (Boiss.) Meikle Fruit and Leaf Extracts
Journal of the Turkish Chemical Society Section A: Chemistry · 2024 TR DİZİN
ARAŞTIRMA GÖREVLİSİ TUĞSEN BÜYÜKYILDIRIM →
Fatty Acid Composition, Antioxidant, and Enzyme Inhibition Activities of Cachrys Crassiloba (Boiss.) Meikle Fruit and Leaf Extracts
Journal of the Turkish Chemical Society Section A: Chemistry · 2024 SCOPUS
PROFESÖR NURANİYE ERUYGUR →
Fatty Acid Composition, Antioxidant, and Enzyme Inhibition Activities of Cachrys Crassiloba (Boiss.) Meikle Fruit and Leaf Extracts
Journal of the Turkish Chemical Society Section A: Chemistry · 2024 TR DİZİN
ARAŞTIRMA GÖREVLİSİ MUHAMMED RAŞİT BAKIR →
Fatty Acid Composition, Antioxidant, and Enzyme Inhibition Activities of Cachrys Crassiloba (Boiss.) Meikle Fruit and Leaf Extracts
Journal of the Turkish Chemical Society Section A: Chemistry · 2024 scopus
PROFESÖR YAVUZ BAĞCI →
Makale Bilgileri
DergiJournal of the Turkish Chemical Society, Section A: Chemistry
Yayın TarihiOcak 2024
Cilt / Sayfa11 · 723-730
Scopus ID2-s2.0-85195120182
Erişim🔓 Açık Erişim
Özet
The genus Cachrys L. (Apiaceae) is distributed in the Mediterranean region and contains 11 spe-cies. C. crassiloba (Boiss.) Meikle is a species that grows in Southwest and Western Anatolia. Considering the literature studies, there were not enough studies on C. crassiloba. In this study, fatty acid composition, total phenol/flavonoid contents, antioxidant and acetyl-butrylcholinesterase, tyrosinase, and α-glucosidase enzyme inhibition activities of n-hexane and ethanol extracts prepared from C. crassiloba fruits and leaves were investigated by spectrophotometric methods at different concentrations. When the results were evaluated, it was found that the hexane extract of C. crassiloba leaf (123.92 ± 4.62 GA mg/g extract) had the highest total phenol content, while the ethanol extract of C. crassiloba fruit (134.38 ± 0.98 QE mg/g extract) had the highest flavonoid content. C. crassiloba hexane and ethanol leaf extracts (IC50= 8.04 ± 1.31 µg/mL; 10.30 ± 3.15 µg/mL) showed good antioxidant activity compared to the ascorbic acid (IC50= 14.59 ± 1.96 µg/mL) in DPPH assay. C. crassiloba leaf ethanol extract (IC50= 17.38 ± 5.02 µg/mL) has the highest ABTS scavenging activity. C. crassiloba extracts have moderate cholinesterase inhibitory activity. C. crassiloba leaf ethanol extract (IC50= 196.65 ± 1.94 µg/mL) has good tyrosinase enzyme inhibition activity. C. crassiloba leaf hexane extract (36.35% ± 1.13) was found to have significant inhibitory activity against α-glucosidase. In conclusion, besides its antioxidant activity, C. crassiloba may be effective against neurodegenerative diseases and skin disorders such as hyperpigmentation and diabetes mellitus, but further phytochemical analysis studies are required.
Yazarlar (4)
1
Tugsen Buyukyildirim
2
Yavuz Bağci
3
Nuraniye Eruygur
4
M. Raşit Bakır
Anahtar Kelimeler
Antioxidant activity
Apiaceae
Cachrys crassiloba
Enzyme inhibition activity
Fatty acid composition
Kurumlar
Gazi Üniversitesi
Ankara Turkey
Selçuk Üniversitesi
Selçuklu Turkey