Scopus
YÖKSİS DOI Eşleşti
SJR Q2
Decision tree-based evaluation of IGF-1 and CAST gene polymorphisms associated with morphometric traits in sheep
Molecular Biology Reports · Aralık 2026
YÖKSİS Kayıtları
Decision tree-based evaluation of IGF-1 and CAST gene polymorphisms associated with morphometric traits in sheep
MOLECULAR BIOLOGY REPORTS · 2026 SCI
Arş. Gör. AYŞE NUR TANIŞ →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Decision tree-based evaluation of IGF-1 and CAST gene polymorphisms associated with morphometric traits in sheep
2026 ISSN: 0301-4851 SCI Q3
Arş. Gör. AYŞE NUR TANIŞ →
Glutathione S-transferase M1 and T1 genotypes and myocardial infarction
2013 ISSN: 0301-4851 IM: Index Medicus
Prof. Dr. TÜLÜN ÇORA →
In vitro antioxidant assessment, screening of enzyme inhibitory activities of methanol and water extracts and gene expression in Hypericum lydium
2019 ISSN: 0301-4851 SCI
Prof. Dr. NURANİYE ERUYGUR →
NF‑ĸβ upregulates ADAMTS5 expression by direct binding after TNF‑α
treatment in OUMS‑27 chondrosarcoma cell line 2020 Jun;47(6):4215-4223
2020 ISSN: 0301-4851 SSCI
Prof. Dr. TÜLÜN ÇORA →
Type 2 diabetes is associated with the MTNR1B gene, a genetic bridge between circadian rhythm and glucose metabolism, in a Turkish population
2021 ISSN: 0301-4851 SCI-Expanded Q4
Arş. Gör. FATMA GÖKTÜRK →
Relationship of endoplasmic reticulum stress with the etiopathogenesis of chronic tonsillitis and tonsillar hypertrophy in pediatric patients: a prospective, parallel-group study
2021 ISSN: 0301-4851 SCI-Expanded Q3
Doç. Dr. MERİH ÖNAL →
Type 2 diabetes is associated with the MTNR1B gene, a genetic bridge
between circadian rhythm and glucose metabolism, in a Turkish
population
2021 ISSN: 0301-4851 SCI-Expanded Q3
Doç. Dr. DUDU ERKOÇ KAYA →
Relationship of endoplasmic reticulum stress with the etiopathogenesis of chronic tonsillitis and tonsillar hypertrophy in pediatric patients: a prospective, parallel-group study
2021 ISSN: 0301-4851 SCI-Expanded Q3
Prof. Dr. İBRAHİM ÖZKAN ÖNAL →
Type 2 diabetes is associated with the MTNR1B gene, a genetic bridge between circadian rhythm and glucose metabolism, in a Turkish population
2021 ISSN: 0301-4851 SCI-Expanded Q4
Dr. Öğr. Üyesi MUSLU KAZIM KÖREZ →
A new approach to sepsis treatment by rasagiline: a molecular, biochemical and histopathological study
2022 ISSN: 0301-4851 SCI-Expanded Q4
Dr. Öğr. Üyesi MUHAMMED YAYLA →
Glutathione S transferase M1 and T1 genotypes and myocardial infarction
2013 ISSN: 0301-4851 SCI
Prof. Dr. HASAN ACAR →
Investigation the effects of bee venom and H-dental-derived mesenchymal stem cells on non-small cell lung cancer cells (A549)
2024 ISSN: 0301-4851 SCI-Expanded Q3
Prof. Dr. HÜSAMETTİN VATANSEV →
Investigation the effects of bee venom and H-dental-derived mesenchymal stem cells on non-small cell lung cancer cells (A549)
2024 ISSN: 0301-4851 SCI-Expanded Q3
Prof. Dr. BAHADIR ÖZTÜRK →
Juglone-ascorbate treatment enhances reactive oxygen species mediated mitochondrial apoptosis in pancreatic cancer
2024 ISSN: 0301-4851 SCI-Expanded Q3
Dr. Öğr. Üyesi DUYGU DURSUNOĞLU →
Juglone-ascorbate treatment enhances reactive oxygen species mediated mitochondrial apoptosis in pancreatic cancer
2024 ISSN: 0301-4851 SCI-Expanded Q3
Doç. Dr. DUDU ERKOÇ KAYA →
Juglone-ascorbate treatment enhances reactive oxygen species mediated mitochondrial apoptosis in pancreatic cancer
2024 ISSN: 0301-4851 SCI-Expanded Q3
Prof. Dr. ESMA MENEVŞE →
Investigation the effects of bee venom and H-dental-derived mesenchymal stem cells on non-small cell lung cancer cells (A549)
2024 ISSN: 0301-4851 SCI-Expanded Q3
Prof. Dr. HÜSAMETTİN VATANSEV →
Investigation of the effects of gabapentin on high glucose-induced neurotoxicity and genotoxicity in an in vitro model of diabetic neuropathy and in silico molecular docking analysis
2025 ISSN: 0301-4851 SCI-Expanded Q3
Dr. Öğr. Üyesi BATUHAN BİLGİN →
Comparison of the neuroprotective effects of gossypin on cisplatin-induced neurotoxicity in vitro and in vivo
2025 ISSN: 0301-4851 SCI-Expanded Q3
Dr. Öğr. Üyesi MUHAMMED YAYLA →
Makale Bilgileri
ISSN03014851
Yayın TarihiAralık 2026
Cilt / Sayfa53
Scopus ID2-s2.0-105031504681
Özet
Background: The IGF-1 (insulin-like growth factor) and CAST (calpastatin) genes have been reported to influence several economically important productivity traits in sheep. This study aimed to investigate the relationship between the genotypes of these two genes, identified by PCR-RFLP (Polymerase Chain Reaction–Restriction Fragment Length Polymorphism) analysis, and growth-related characteristics in Anatolian Merino and Akkaraman sheep. Methods and results: In addition to live weight (LW), morphometric measurements including rump height (RH), withers height (WH), body length (BL), chest depth (CD), chest width (CW), and chest circumference (CC) were recorded. IGF-1 genotypes were identified using HaeIII digestion, revealing three genotypes (CC, CG, and GG), while CAST genotypes were determined by MspI digestion, yielding two genotypes (MM and MN). Associations between genotypes and traits were evaluated through analysis of variance and CHAID regression tree analysis, and breed comparisons were performed using t-tests. Anatolian Merino sheep exhibited higher LW, BL, CW, and CC, whereas Akkaraman sheep showed greater RH and WH. No significant association between IGF-1 genotypes and morphometric traits was observed in Anatolian Merino sheep; however, in Akkaraman sheep, the IGF-1 GG genotype was significantly associated with higher LW, RH, WH, CW, and CC. CAST genotypes were not related to any of the examined traits, and regression tree analysis supported these results. Conclusions: Overall, the results suggest that IGF-1 genotypes, particularly GG, could be valuable for marker-assisted selection (MAS) programmes targeting live weight and body measurements in sheep.
Yazarlar (3)
1
Fatma Ilhan
2
Ayşe Nur Tanış
ORCID: 0000-0002-4369-0916
3
İsmail Keskin
Anahtar Kelimeler
CAST
CHAID
IGF-1
Live weight
PCR-RFLP
Sheep
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Molecular Biology Reports
Q2
SJR Skoru0,710
H-Index96
YayıncıSpringer Science and Business Media B.V.
ÜlkeNetherlands
Genetics (Q2)
Medicine (miscellaneous) (Q2)
Molecular Biology (Q3)