Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Effects of mild and moderate hypothermia on renal injury evaluated with neutrophil gelatinase associated lipocalin cystatin C and near infrared spectroscopy in patients undergoing cardiopulmonary bypass graft surgery
Cardiovascular Journal of Africa · Eylül 2025
YÖKSİS Kayıtları
Effects of mild and moderate hypothermia on renal injury evaluated with neutrophil gelatinase associated lipocalin cystatin C and near infrared spectroscopy in patients undergoing cardiopulmonary bypass graft surgery
Cardiovascular Journal of Africa · 2025 SCI-Expanded
PROFESÖR OĞUZHAN ARUN →
Effects of mild and moderate hypothermia on renal injury evaluated with neutrophil gelatinase associated lipocalin cystatin C and near infrared spectroscopy in patients undergoing cardiopulmonary bypass graft surgery
Cardiovascular Journal of Africa · 2025 SCI-Expanded
PROFESÖR BAHAR ÖÇ →
Effects of mild and moderate hypothermia on renal injury evaluated with neutrophil gelatinase associated lipocalin cystatin C and near infrared spectroscopy in patients undergoing cardiopulmonary bypass graft surgery
Cardiovascular Journal of Africa · 2025 SCI-Expanded
PROFESÖR MEHMET ALKILIÇ HORASANI ÖÇ →
Makale Bilgileri
DergiCardiovascular Journal of Africa
Yayın TarihiEylül 2025
Cilt / Sayfa36 · 280-286
Scopus ID2-s2.0-105032341899
Erişim🔓 Açık Erişim
Özet
BACKGROUND: The degree of hypothermia during coronary artery bypass grafting (CABG) surgery may affect kidney injury. In this study we compared the effects of mild (MLD) and moderate (MOD) hypothermia on renal injury evaluated with Neutrophil Gelatinase Associated Lipocalin (NGAL), Cystatin-C (Cyc-C) and Near Infrared Spectroscopy (NIRS) in CABG surgery. METHODS: With institutional approval, 40 adult patients CABG with CPB were divided into two groups; mild hypothermia, (320C) (MLD group) (n = 20) and moderate hypothermia (280C) (MOD group) (n = 20). Urinary NGAL and serum Cyc-c were measured preoperatively (t1) and at postoperative 6th (t2), 12th (t3), 24th (t4) and 48th (t5) hours and NIRS values were recorded during intraoperative and postoperative 12 hours, and at postoperative 24th and 48th hours. Appropriate tests were used for Statistical analysis, p < 0.05 = significant. RESULTS: AKI occurred in five patients of the MLD group and one patient in MOD group (p < 0.05). Urinary NGAL and serum Cyc-C levels were higher in MLD group (p < 0.05). No correlation existed between intraoperative NIRS values and postoperative NGAL values. Moderate correlation was found between intraoperative NIRS and postoperative Cyc-C and serum creatinine (p < 0.05). CONCLUSION: Our results indicate that MOD hypothermia is more protective regarding renal function. NIRS values are not sufficient enough in terms of clinical follow-up.
Yazarlar (6)
1
Serkan Yildirim
2
Bahar Oc
ORCID: 0000-0002-2253-5191
3
Murat Simsek
4
Feyza Tülek
5
Oguzhan Arun
ORCID: 0000-0001-6101-1481
6
Mehmet Oc
ORCID: 0000-0002-7832-3067
Anahtar Kelimeler
acute kidney injury
cardiac surgery
hypothermia
Kurumlar
Konya City Hospital
Konya Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Üniversitesi
Selçuklu Turkey