Scopus
YÖKSİS Eşleşti
The Impact of the Number of Sutures on Regeneration in Nerve Repair
Annals of Plastic Surgery · Mart 2024
YÖKSİS Kayıtları
The Impact of the Number of Sutures on Regeneration in Nerve Repair
Annals of Plastic Surgery · 2024 SCI-Expanded
DOÇENT ALİ ÖZDEMİR →
The Impact of the Number of Sutures on Regeneration in Nerve Repair
ANNALS OF PLASTIC SURGERY · 2024 SCI
DOKTOR ÖĞRETİM ÜYESİ EBUBEKİR ERAVŞAR →
The Impact of the Number of Sutures on Regeneration in Nerve Repair
Annals of Plastic Surgery · 2023 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ EBUBEKİR ERAVŞAR →
Makale Bilgileri
DergiAnnals of Plastic Surgery
Yayın TarihiMart 2024
Cilt / Sayfa92 · 313-319
Scopus ID2-s2.0-85185824718
Özet
Purpose The ideal number of sutures for epineural nerve repair is still unclear. Increased number of sutures increases secondary damage and inflammation to the nerve tissue, which negatively affects nerve regeneration. When the number of sutures decreases, the strength of the nerve repair site decreases and nerve endings are fringed, which also negatively affects nerve regeneration. Therefore, each additional suture is not only beneficial but also detrimental. The aim of this study was to find out the ideal number of sutures for nerve repair. Methods Seventy rats were randomly divided into 5 groups. One of the groups was used as a control group, and right sciatic nerves of the rats in other 4 groups were repaired by using 2, 3, 4, or 6 epineural sutures, respectively, after nerve transection. Biomechanical assessment was performed on the nerves collected from these rats at 5 days of follow-up. Functional and histological analyses were evaluated after 12 weeks of follow-up. Results It was found that an increase in the number of sutures enhances resistance to tensile force in general. However, there was no significant biomechanical difference between the 6-sutured group in which the most sutures were used and the 4-sutured group. In functional examinations, overall successful results were obtained in the group with 4 sutures. In histological examinations, there was no statistical difference between the control group, 2-sutured groups, and 4-sutured groups in terms of connective tissue index. However, it was observed that the group with 6 sutures had a higher connective tissue index than the control group and groups with 2 and 4 sutures. In terms of regeneration index, it was found that repair with 4 sutures was superior to repair with 2 and 6 sutures. No difference was found between any of the suture groups according to the diameter change index. Conclusions These results indicate that repair with 4 sutures is the best method of epineural repair that provides both strength and regeneration. These findings will contribute to both the repair of clinically similar nerves and the standardization of rat nerve studies.
Yazarlar (4)
1
Ebubekir Eravşar
ORCID: 0000-0003-2940-604X
2
Ali Özdemir
ORCID: 0000-0002-8835-9741
3
Gokhan Cuce
4
Mehmet Ali Acar
Anahtar Kelimeler
epineural repair
nerve regeneration
nerve repair
standardization
suture number
Kurumlar
Konya City Hospital
Konya Turkey
Meram State Hospital
Konya Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
1
Atıf
4
Yazar
5
Anahtar Kelime