Scopus
YÖKSİS Eşleşti
Sulforaphane effect on antioxidant and anti-inflammatory responses on healthy lung cells treated graphene oxide nanoparticles
Microchemical Journal · Haziran 2025
YÖKSİS Kayıtları
Sulforaphane effect on antioxidant and anti-inflammatory responses on healthy lung cells treated graphene oxide nanoparticles
MICROCHEMICAL JOURNAL · 2025 SCI-Expanded
ARAŞTIRMA GÖREVLİSİ KÜBRA YILMAZ →
Sulforaphane effect on antioxidant and anti-inflammatory responses on healthy lung cells treated graphene oxide nanoparticles
Microchemical Journal · 2025 SCI-Expanded
PROFESÖR ESMA MENEVŞE →
Makale Bilgileri
DergiMicrochemical Journal
Yayın TarihiHaziran 2025
Cilt / Sayfa213
Scopus ID2-s2.0-105004271567
Özet
This study aimed to determine the effects of graphene oxide nanomaterial, used in many areas of life, such as the cleansing of harmful substances such as reactive oxygene species from the body or living organisms. The phytochemicals produced from plants provide resistance to oxidative stress. The healthy lung cell line BEAS-2B was chosen for this study. To measure the effectiveness of graphene oxide and its derivatives, which can be found in every area of life, healthy lungs were chosen as the guide would see. In this study, graphene oxide nanoparticles were synthesized from graphites (50 and 400 nm) by activating nanoparticles’ surfaces by the Hummers method. SEM, TEM, Zeta Potential and FT-IR analysis were carried out for characterization of nanoparticles. IC<inf>50</inf> values were calculated separately for each graphene oxide nanoparticles (G50 and G400), and then the nanoparticles were applied to healthy lungs above, below and exactly at these values. Sulforaphane is a bioactive phytochemical that was chosen as the reference substance to determine the effect on Interleucin-6 (IL-6) level, Total Superoxide Dismutase (T-SOD), and Glutathione Peroxidase (GSH-Px) activities of G50 and G400-treated cells. At this point, sulforaphane (SF) showed strong anti-inflammatory and antioxidant properties on lung cells.
Yazarlar (5)
1
Kubra Yilmaz Kuvvet
2
Emine N. Korucu
3
Fatih Ozcan
4
Esma Menevşe
5
Esra Maltas Cagil
Anahtar Kelimeler
Anti-inflammatory effect
Antioxidant activity
Graphene oxide
Size effect
Sulforaphane
Kurumlar
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Tip Fakültesi
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
1
Atıf
5
Yazar
5
Anahtar Kelime