Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q4
The Potential Protective Effects of Quercetin Treatment on Hippocampal Tissue of Wistar Rats Exposed to Cadmium
Eurasian Journal of Veterinary Sciences · Ocak 2025
YÖKSİS Kayıtları
The Potential Protective Effects of Quercetin Treatment onHippocampal Tissue of Wistar Rats Exposed to Cadmium
Eurasian Journal of Veterinary Sciences · 2025 Scopus, Zoological record
Dr. Öğr. Üyesi İLKNUR ÜNDAĞ →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Serological and virological investigation of bovine viral diarrhea virus infection in cattle with abortion problem
2013 ISSN: 1309-6958 ULAKBİM-YAŞAM BİLİMLERİ
Prof. Dr. OĞUZHAN AVCI →
Antibody prevalence against respiratory viruses in naturally infected cattle in Central Anatolia
2014 ISSN: 1309-6958 ULAKBİM-YAŞAM BİLİMLERİ
Prof. Dr. OĞUZHAN AVCI →
Disseminated metastatic transmissible venereal tumour in a bitch
2013 ISSN: 1309-6958 TR DİZİN 1 atıf
Prof. Dr. MEHMET MADEN →
Investigation on Listeria spp. in Patrige Meat
2014 ISSN: 1309-6958 ULAKBİM TR DİZİN, CAB Abstracts, Index Copernicus
Prof. Dr. GÜRKAN UÇAR →
Pastörize sıvı yumurta ile kabuklu yumurtanın bazı kalite özellikleri bakımından kıyaslanması
2015 ISSN: 1309-6958 ULAKBİM TR DİZİN, CAB Abstracts, Index Copernicus
Prof. Dr. AHMET GÜNER →
Barınak Köpeklerinde Canine Coronavirus Varlığının Belirlenmesi
2015 ISSN: 1309-6958 TR DİZİN
Doç. Dr. IRMAK DİK →
Microbiological quality of red meat pieces
2015 ISSN: 1309-6958 Türkiye Atıf Dizini *EBSCO-HOST*Cab Abstracts*Veterinary Bulletin*Veterinary Science Database*Index Veterinarius*Dairy Science Abstracts *Animal Breeding Abstracts*Agricultural Engineering Abstracts *Global Health*World Agricultural Economics and Rural Sociology Abstracts *Forest Products Abstracts
Prof. Dr. ÜMİT GÜRBÜZ →
Nerium Oleander Distilatının Antimikrobiyal Etkisinin Araştırılması
2013 ISSN: 1309-6958 TR DİZİN
Prof. Dr. BURAK DİK →
Doksorubisinin neden olduğu organ hasarlarında Nerium Oleander distilatının koruyucu etkinliğinin belirlenmesi
2014 ISSN: 1309-6958 TR DİZİN
Prof. Dr. BURAK DİK →
Koyunlarda Tarantula cubensis alkolik ekstraktının (Theranekron) serum tiyobarbitürik asit reaktif ürünlerine etkisi
2014 ISSN: 1309-6958 TR DİZİN
Prof. Dr. BURAK DİK →
Pathological and microbiological investigations on the lesions of the respiratory systems of laying hens
2008 ISSN: 1309-6958 *TÜBİTAK-ULAKBİM-YAŞAM BİLİMLERİ *Türkiye Atıf Dizini *EBSCO-HOST *Cab Abstracts *Veterinary Bulletin *Veterinary Science Database *Index Veterinarius *Dairy Science Abstracts *Animal Breeding Abstracts *Agricultural Engineering Abstracts *Global Health *World Agricultural Economics and Rural Sociology Abstracts *Forest Products Abstracts *Grasslands and Forage Abstracts *Helminthological Abstracts *Rural Development Abstracts *Soils and Fertilizers *Soybean Abstracts *Sugar Industry Abstracts *Tropical Disaeases Bulletin *Wheat, Barley and Tritacale Abstracts *Maize Abstracts
Prof. Dr. ÖZGÜR ÖZDEMİR →
The retrospective evaluations of the neoplastic cases of dog between 2006 to 2011
2013 ISSN: 1309-6958 *TÜBİTAK-ULAKBİM-YAŞAM BİLİMLERİ*Türkiye Atıf Dizini*EBSCO-HOST*Cab Abstracts*Veterinary Bulletin*Veterinary Science Database*Index Veterinarius*Dairy Science Abstracts*Animal Breeding Abstracts*Agricultural Engineering Abstracts*Global Health*World Agricultural Economics and Rural Sociology Abstracts*Forest Products Abstracts*Grasslands and Forage Abstracts*Helminthological Abstracts*Rural Development Abstracts*Soils and Fertilizers*Soybean Abstracts*Sugar Industry Abstracts*Tropical Disaeases Bulletin*Wheat, Barley and Tritacale Abstracts*Maize Abstracts
Prof. Dr. ÖZGÜR ÖZDEMİR →
Bir İnekte Melanom Olgusu
2006 ISSN: 1309-6958 *TÜBİTAK-ULAKBİM-YAŞAM BİLİMLERİ*Türkiye Atıf Dizini*EBSCO-HOST*Cab Abstracts*Veterinary Bulletin*Veterinary Science Database*Index Veterinarius*Dairy Science Abstracts*Animal Breeding Abstracts*Agricultural Engineering Abstracts*Global Health*World Agricultural Economics and Rural Sociology Abstracts*Forest Products Abstracts*Grasslands and Forage Abstracts*Helminthological Abstracts*Rural Development Abstracts*Soils and Fertilizers*Soybean Abstracts*Sugar Industry Abstracts*Tropical Disaeases Bulletin*Wheat, Barley and Tritacale Abstracts*Maize Abstracts
Prof. Dr. ÖZGÜR ÖZDEMİR →
Ham ayçiçek yağı yerine yan ürünlerinin yumurta tavuklarında enerji kaynağı olarak kullanımı
1994 ISSN: 1309 - 6958 TR DİZİN
Prof. Dr. TAHİR BALEVİ →
Serbest ve korunmuş formdaki asit yağın süt ineklerinde rumen fermentasyonu ve süt verimi üzerine etkileri
2000 ISSN: 1309 - 6958 TR DİZİN
Prof. Dr. HUZUR DERYA ARIK →
Geçiş dönemindeki süt ineklerinde gliserol kullanımının etkileri
2010 ISSN: 1309 - 6958 TR DİZİN
Prof. Dr. TAHİR BALEVİ →
Bazı et ürünlerinde E coli O157 H7 varlığının araştırılması
2010 ISSN: 1309-6958 EBSCO-HOST*Cab Abstracts*Veterinary Bulletin*Veterinary Science Database*Index Veterinarius 1 atıf
Prof. Dr. ÜMİT GÜRBÜZ →
Karaman ilinde yetiştirilen koyunlarda Blue Tongue Virus enfeksiyonunun serolojik olarak araştırılması
2015 ISSN: 1309-6958 TÜBİTAK Yaşam Bilimleri, CAB Abstracts, Vet Bull, EBSCO, Vet Sci Database vs...
Prof. Dr. ATİLLA ŞİMŞEK →
Yerli merkeplerde vena portae’nın karaciğer içerisindeki dağılımı üzerine makroanatomik araştırmalar
2014 ISSN: 1309-6958 Cab Abstract
Prof. Dr. MUSTAFA ORHUN DAYAN →
Makale Bilgileri
ISSN13096958
Yayın TarihiOcak 2025
Cilt / Sayfa41
Scopus ID2-s2.0-105026705190
Erişim🔓 Açık Erişim
Özet
This study aimed to assess the neuroprotective potential of quercetin (Q) against cadmium (Cd)-induced toxicity by evaluating its impact on antioxidant enzyme activities, cytokine profiles, neuronal survival, and histopathological alterations in the hippocampal tissue of rats. Twenty four healthy male Wistar albino rats were randomly assigned into four groups: control (C; n = 6), cadmium (Cd; n = 6), quercetin (Q; n = 6), and cadmium + quercetin (Cd+Q; n = 6). CdCl<inf>2</inf> was administered subcutaneously at 4 mg/kg/day for three days to the Cd and Cd+Q groups. Simultaneously, quercetin was administered intraperitoneally at 50 mg/kg/day to the Q and Cd+Q groups. The hippocampal tissues were collected post-treatment for biochemical, histopathological, and cellular analyses. Cadmium exposure led to oxidative stress, elevated pro-inflammatory cytokines, suppressed antioxidant defenses, and neuronal degeneration in the hippocampus. Quercetin treatment partially mitigated these effects by enhancing antioxidant markers (GSH, SOD), modulating cytokine levels (notably IL-1), and preserving neuronal integrity, particularly in the CA1, CA2, CA3, and dentate gyrus regions (p < 0.05). These findings suggest that quercetin confers partial neuroprotection against cadmium-induced hippocampal damage through its antioxidative and anti-inflammatory properties. While not entirely preventive, quercetin may serve as a supportive therapeutic agent in countering heavy metal-induced neurotoxicity.
Yazarlar (5)
1
M. Özsan
2
Ihsan Kisadere
ORCID: 0000-0003-0732-0464
3
Ündag
4
Nurcan Dönmez
5
Hasan Hüseyin Dönmez
Anahtar Kelimeler
Cadmium neurotoxicity
Cytokine modulation
Hippocampal oxidative stress
Neuroprotection
Quercetin
Kurumlar
Balikesir Üniversitesi
Balikesir Turkey
Niğde Ömer Halisdemir University
Nigde Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Eurasian Journal of Veterinary Sciences
Q4
OA
SJR Skoru0,178
H-Index5
YayıncıSelcuk Universitesi, Veteriner Fakultesi
ÜlkeTurkey
Veterinary (miscellaneous) (Q4)
Metrikler
2
Atıf
5
Yazar
5
Anahtar Kelime