Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Comparison of the CoaguChek XS handheld coagulation analyzer and conventional laboratory methods measuring international normalised ratio (INR) values during the time to therapeutic range after mechanical valve surgery
Journal of Cardiac Surgery · Mayıs 2013
YÖKSİS Kayıtları
Comparison of the CoaguChek XS Handheld Coagulation Analyzer and Conventional Laboratory Methods Measuring International Normalised Ratio (INR) Values during the Time to Therapeutic Range after Mechanical Valve Surgery
Journal of Cardiac Surgery · 2013 SCI-Expanded
DOÇENT ÖMER FARUK ÇİÇEK →
Makale Bilgileri
DergiJournal of Cardiac Surgery
Yayın TarihiMayıs 2013
Cilt / Sayfa28 · 254-257
Scopus ID2-s2.0-84877801747
Erişim🔓 Açık Erişim
Özet
Aim: To compare the international normalised ratio (INR) value of patients evaluated using the CoaguChek XS versus conventional laboratory methods, in the period after open-heart surgery for mechanical valve replacement until a therapeutic range is achieved using vitamin K antagonists (VKA) together with low molecular weight heparin (LMWH). Methods: One hundred and five patients undergoing open-heart surgery for mechanical valve replacement were enrolled. Blood samples were collected from patients before surgery, and on the second and fifth postoperative days, simultaneously for both the point of care device and conventional laboratory techniques. Patients were administered VKA together with LMWH at therapeutic doses (enoxaparin 100 IU/kg twice daily) subcutaneously, until an effective range was achieved on approximately the fifth day after surgery. Results: The mean INR values using the CoaguChek XS preoperatively and on the second and fifth days postoperatively were 1.20 (SD ± 0.09), 1.82 (SD ± 0.45), and 2.55 (SD ± 0.55), respectively. Corresponding results obtained using conventional laboratory techniques were 1.18 (SD ± 0.1), 1.81 (SD ± 0.43), and 2.51 (SD ± 0.58). The correlation coefficient was r = 0.77 preoperatively, r = 0.981 on postoperative day 2, and r = 0.983 on postoperative day 5. Discussion: Results using the CoaguChek XS Handheld Coagulation Analyzer correlated strongly with conventional laboratory methods, in the bridging period between open-heart surgery for mechanical valve replacement and the achievement of a therapeutic range on warfarin and LMWH. © 2013 Wiley Periodicals, Inc.
Yazarlar (7)
1
Hasmet Bardakci
2
Garip Altıntaş
3
Ömer Faruk Çiçek
ORCID: 0000-0002-4675-3273
4
Umit Kervan
5
Sevinc Yilmaz
6
Sadi Kaplan
7
Cemal Levent Birincioglu
Kurumlar
Turkiye Yuksek Ihtisas Hospital
Ankara Turkey
Metrikler
6
Atıf
7
Yazar