Scopus
YÖKSİS ISSN Eşleşti
SJR Q1
Enhancing antimicrobial activity and reducing cytotoxicity of silver nanoparticles through gelatin nanoparticles
Nanomedicine · Şubat 2024
YÖKSİS Kayıtları — ISSN Eşleşmesi
Investigation of in vitro antimicrobial and cytotoxic effects of gold nanoparticles capped with meropenem and imipenem
2023 ISSN: 1743-5889 SCI-Expanded Q1
Prof. Dr. İDRİS SARGIN →
Investigation of in vitro antimicrobial and cytotoxic effects of gold nanoparticles capped with meropenem and imipenem
2023 ISSN: 1743-5889 SCI-Expanded Q1
Prof. Dr. GÜLŞİN ARSLAN →
Investigation of in vitro antimicrobial and
cytotoxic effects of gold nanoparticles
capped with meropenem and imipenem
2023 ISSN: 1743-5889 SCI-Expanded Q1
Prof. Dr. UĞUR ARSLAN →
Investigation of in vitro antimicrobial and cytotoxic effects of gold nanoparticles capped with meropenem and imipenem
2023 ISSN: 1743-5889 SCI
Prof. Dr. SERDAR KARAKURT →
Makale Bilgileri
Dergi
Nanomedicine
ISSN17435889
Yayın TarihiŞubat 2024
Cilt / Sayfa19 · 199-211
Scopus ID2-s2.0-85184305198
Özet
Aim: To develop a novel stabilizing agent for silver nanoparticles (AgNPs) with the aim of enhancing its antibacterial efficacy against wound associated pathogens while mitigating their cytotoxic effect on human cells. Materials & methods: In this study, monodispersed gelatin nanoparticles were synthesized to stabilize AgNPs. The stability, antibacterial activity and biocompatibility of the gelatin-stabilized AgNPs (Gel-AgNPs) were compared with citrate-stabilized AgNPs (citrate-AgNPs) or silver ions. Results & conclusion: Gelatin-stabilized AgNPs showed significantly better antibacterial activities compared with citrate-stabilized AgNPs against both Gram-positive and Gram-negative bacteria. These Gel-AgNPs showed significantly lower cytotoxicity to human dermal fibroblasts compared with Ag<sup>+</sup>. These findings provided the first evidence substantiating a novel functionality of gelatin nanoparticles in both stabilizing and enhancing the activity of AgNPs.
Yazarlar (3)
1
Derya Ozhava
ORCID: 0000-0003-4747-7490
2
Petras Winkler
3
Yong Mao
ORCID: 0000-0001-9268-4523
Anahtar Kelimeler
antimicrobial activity
cytotoxicity
gelatin nanoparticles
human dermal fibroblasts
silver ion
silver nanoparticles
Kurumlar
Rutgers University–New Brunswick
New Brunswick United States
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Nanomedicine
Q1
SJR Skoru0,681
H-Index148
YayıncıTaylor and Francis Ltd.
ÜlkeUnited Kingdom
Development (Q1)
Bioengineering (Q2)
Biomedical Engineering (Q2)
Materials Science (miscellaneous) (Q2)
Medicine (miscellaneous) (Q2)
Nanoscience and Nanotechnology (Q2)
Metrikler
8
Atıf
3
Yazar
6
Anahtar Kelime