Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Elevated Serum Uric Acid to HDL-Cholesterol Ratio is Related to Cardiovascular Risk in Patients Receiving Hemodialysis
Genel Tip Dergisi · Nisan 2022
YÖKSİS Kayıtları
Elevated Serum Uric Acid to HDL-Cholesterol Ratio is Related to Cardiovascular Risk in Patients Receiving Hemodialysis
Genel Tıp Dergisi · 2022 TR DİZİN
DOÇENT AHMET ÇİZMECİOĞLU →
Elevated Serum Uric Acid to HDL-Cholesterol Ratio is Related to Cardiovascular Risk in Patients Receiving Hemodialysis
Selcuk University · 2022 TR DİZİN
PROFESÖR YASEMİN COŞKUN YAVUZ →
Elevated Serum Uric Acid to HDL-Cholesterol Ratio is Related to Cardiovascular Risk in Patients Receiving Hemodialysis
Selcuk University · 2022 TR DİZİN
PROFESÖR ZEYNEP BIYIK →
Makale Bilgileri
DergiGenel Tip Dergisi
Yayın TarihiNisan 2022
Cilt / Sayfa32 · 159-166
Scopus ID2-s2.0-105009238500
Erişim🔓 Açık Erişim
Özet
Aim: Chronic kidney disease (CKD) is a progressive disease in which frequent cardiovascular (CV) comorbidities. High uric acid to HDL-cholesterol ratio (UHR) results were quite notable in patients receiving peritoneal dialysis. Thus, in this study, we aimed to evaluate the UHR results in dialysis patients. Materials and Methods: This retrospective, multicenter, cross-sectional study was conducted with CKD patients, and the control group consisted of hypertensive patients with a normal glomerular filtration rate (GFR). Patients’ laboratory, ambulatory blood pressure monitoring, and demographic records were obtained from the follow-up cases of two university hospitals’ internal medicine and nephrology departments. The patients’ group then were divided into five subsets according to GFR. Results: A total of 124 CKD patients and 127 control participated in this study. All CKD patients were also identified as pre-dialysis and dialysis. The cases of UHR, non-dipper blood pressure pattern, and nocturnal heart rate (HR) were increased in CKD compared to the control group. Per disease progression, the non-dipper HR and nocturnal HR were more significant in patients receiving dialysis with high UHR than in the pre-dialysis subset. In diabetic patients with an on-targeted HbA1c, those with high UHRs still had nocturnal diastolic BP elevations. Finally, there was not an exact stage-specific result for pulse wave velocity. Conclusions: Based on our results, dialysis patients with high UHRs have higher non-dipper pulse rate, nocturnal heart rate, and nocturnal diastole blood pressure, associated with CV risk. Despite well-managed diabetes, elevated UHR in dialysis patients may be associated with non-dipper hypertension.
Yazarlar (6)
1
Ahmet Cizmecioglu
2
Mevlut Hakan Goktepe
3
Hilal Cizmecioglu
4
Zeynep Bıyık
5
Yasemin Coşkun Yavuz
6
Lütfullah Altıntepe
Anahtar Kelimeler
Ambulatory blood pressure monitoring
Cardiovascular risk
Diabetes mellitus
Hemodialysis
High-density lipoprotein
Serum uric acid
Kurumlar
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Tip Fakültesi
Konya Turkey