Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Relationship of admission neutrophil-to-lymphocyte ratio with in-hospital mortality in patients with acute type i aortic dissection
Turkish Journal of Medical Sciences · Ocak 2014
YÖKSİS Kayıtları
Relationship of admission neutrophil-to-lymphocyte ratio with in-hospital mortality in patients with acute type I aortic dissection
TURKISH JOURNAL OF MEDICAL SCIENCES · 2014 SCI-Expanded
DOÇENT ÖMER FARUK ÇİÇEK →
Makale Bilgileri
DergiTurkish Journal of Medical Sciences
Yayın TarihiOcak 2014
Cilt / Sayfa44 · 186-192
Scopus ID2-s2.0-84892383598
Erişim🔓 Açık Erişim
Özet
Aim: Acute aortic dissection is a life-threatening cardiovascular emergency. Neutrophil-to-lymphocyte ratio is proposed as a prognostic marker and found to be related to worse clinical outcomes in various cardiovascular diseases. Te aim of the present study was to evaluate the relationship between admission neutrophil-to-lymphocyte ratio and in-hospital mortality in acute type I aortic dissection. Materials and methods: We retrospectively evaluated 123 consecutive patients who had undergone emergent surgery for acute type I aortic dissection. Patients were divided into 2 groups as patients dying in the hospital (Group 1) and those discharged alive (Group 2). All parameters, including neutrophil-to-lymphocyte ratio, were compared between the 2 groups and predictors of mortality was estimated by using multivariate analysis. Results: A total of 104 patients (79 males, mean age: 55.2 ± 14 years) were included in the fnal analysis. In multivariate analyses, cross-clamp time, cardiopulmonary bypass time, intensive care unit duration, platelet count, and neutrophil-to-lymphocyte ratio were found to be independent predictors of mortality. Patients with higher neutrophil-to-lymphocyte ratios had a signifcantly higher mortality rate (hazard ratio: 1.05; 95% CI: 1.01-1.10; P = 0.033). Receiver operating characteristic analysis revealed that using a cut-of point of 8, neutrophil-to-lymphocyte ratio predicts mortality with a sensitivity of 70% and specifcity of 53%. Conclusion: Tis study suggests that admission neutrophil-to-lymphocyte ratio is a potential predictive parameter for determining the in-hospital mortality of acute type I aortic dissection. © TÜBİTAK.
Yazarlar (12)
1
Gökhan Lafçi
ORCID: 0000-0002-0639-4341
2
Ömer Faruk Çiçek
ORCID: 0000-0002-4675-3273
3
Haci Alper Uzun
4
Adnan Yalçinkaya
5
Adem Diken
6
Osman Turak
7
Kumral Çaǧli
8
İrfan Taşoğlu
9
Hikmet Selçuk Gedik
10
Kemal Korkmaz
11
Orhan Eren Günertem
12
Kerim Cagli
Anahtar Kelimeler
Aortic dissection
Mortality
Neutrophil-to-lymphocyte ratio
Kurumlar
Ankara Numune Hospital
Ankara Turkey
Hitit University
Corum Turkey
Turkiye Yuksek Ihtisas Hospital
Ankara Turkey
Metrikler
25
Atıf
12
Yazar
3
Anahtar Kelime