Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q3
The effects of isoflurane, sevoflurane, and desflurane anesthesia on neurocognitive outcome after cardiac surgery: A pilot study
Heart Surgery Forum · Şubat 2007
YÖKSİS Kayıtları
The Effects of Isoflurane, Sevoflurane, and Desflurane Anesthesia on Neurocognitive Outcome after Cardiac Surgery: A Pilot Study
The Heart Surgery Forum · 2007 SCI-Expanded
Prof. Dr. BAHAR ÖÇ →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Cardiac Angiosarcoma: A Case with Bilateral Pleural and Pericardial Effusion
2014 ISSN: 1098-3511 SCI-Expanded Q4
Prof. Dr. BAHAR ÖÇ →
Cardiac Angiosarcoma A Case with Bilateral Pleural and Pericardial Effusion
2013 ISSN: 1098-3511 SCI-Expanded
Prof. Dr. OĞUZHAN ARUN →
Preoperative Fibrinogen Levels as a Predictor of Postoperative Bleeding after Open Heart Surgery
2007 ISSN: 1098-3511 SCI-Expanded
Prof. Dr. BAHAR ÖÇ →
Extremely Low Birth Weight Infants with Patent Ductus Arteriosus Searching for the Least Invasiveness
2012 ISSN: 1098-3511 SCI-Expanded
Prof. Dr. MEHMET ALKILIÇ HORASANI ÖÇ →
Spontaneous Coronary Artery Dissections Three Case Reports and Review of Literature
2012 ISSN: 1098-3511 SCI-Expanded
Prof. Dr. MEHMET ALKILIÇ HORASANI ÖÇ →
Surgical Treatment of Right Ventricular Hydatid Cyst
2012 ISSN: 1098-3511 SCI-Expanded
Prof. Dr. MEHMET ALKILIÇ HORASANI ÖÇ →
Noncompaction of Ventricular Myocardium in a Patient with Congenitally Corrected Transposition of the Great Arteries Treated Surgically Case Report
2005 ISSN: 1098-3511 SCI-Expanded 12 atıf
Prof. Dr. MEHMET ALKILIÇ HORASANI ÖÇ →
Giant Right Atrial Myxoma Mimicking Hepatic Cirrhosis A Case Report
2007 ISSN: 1098-3511 SCI-Expanded 4 atıf
Prof. Dr. MEHMET ALKILIÇ HORASANI ÖÇ →
Predictive Significance of Plasma Levels of Interleukin 6 and High Sensitivity C Reactive Protein in Atrial Fibrillation after Coronary Artery Bypass Surgery
2007 ISSN: 1098-3511 SCI-Expanded 31 atıf
Prof. Dr. MEHMET ALKILIÇ HORASANI ÖÇ →
The Effects of Isoflurane, Sevoflurane, and Desflurane Anesthesia on Neurocognitive Outcome after Cardiac Surgery: A Pilot Study
2007 ISSN: 1098-3511 SCI-Expanded
Prof. Dr. BAHAR ÖÇ →
Preoperative fibrinogen levels as a predictor of postoperative bleeding after open heart surgery
2007 ISSN: 1098-3511 SCI-Expanded 19 atıf
Prof. Dr. MEHMET ALKILIÇ HORASANI ÖÇ →
Comparison of Anterior Mitral Leaflet Repair Techniques with and without the Use of Chordal Replacement in Patients with Degenerative Mitral Valve Insufficiency
2019 ISSN: 1098-3511 SCI-Expanded Q4
Doç. Dr. ÖMER FARUK ÇİÇEK →
The Relationship between Low Intraoperative Hematocrit Levels during Cardiopulmonary Bypass and Postoperative Neurological Events
2013 ISSN: 1098-3511 SCI-Expanded Q4
Doç. Dr. ÖMER FARUK ÇİÇEK →
Makale Bilgileri
Dergi
Heart Surgery Forum
ISSN10983511
Yayın TarihiŞubat 2007
Cilt / Sayfa10 · 17-22
Scopus ID2-s2.0-33847129737
Erişim🔓 Açık Erişim
Özet
Background. Inhalation anesthetics such as isoflurane, sevoflurane, and desflurane are widely used in clinical practice; however, there is no study for comparing these drugs in cardiac surgery with respect to postoperative cognitive outcome and S100 beta protein (S100 BP) levels. In this study, we evaluated the effect of sevoflurane, isoflurane, and desflurane anesthesia on neuropsychological outcome and S100 BP levels in patients undergoing coronary artery bypass grafting (CABG) surgery with cardiopulmonary bypass (CPB). Materials and Methods. Forty-two male patients were prospectively randomized and classified into 3 groups according to the volatile agents used; isoflurane, sevoflurane, desflurane. All patients had a sufficient education level to participate in neuropsychological testing and a normal carotid Doppler ultrasonography. Blood samples for analysis of S100 BP were collected before anesthesia (T1), before heparinization (T2), 15 minutes into CPB (T3), following protamine administration (T4), postoperatively (T5), 24 hours after the operation (T6), postoperative day 3 (T7), and postoperative day 6 (T8). The neuropsychological tests, including Mini-Mental State Examination (MMSET) and visual-aural digit span test (VADST), were administered 1 day prior to surgery and on the third and sixth postoperative days. Results. The postoperative third and sixth day MMSET scores and third day visual-written subtest scores in the sevoflurane group were significantly lower than in the isoflurane and desflurane groups (P < .05). S100 BP levels increased with the beginning of anesthesia in the sevoflurane and desflurane groups. Although S100 BP decreased to baseline levels on postoperative day 1 in the sevoflurane group, this was significantly higher on the third and sixth days postoperatively in the desflurane group (P < .05). In the isoflurane group, the S100 BP level was significantly higher than the baseline level only after CPB (P < .05). Conclusion. Our study suggests that isoflurane is associated with better neurocognitive functions than desflurane or sevoflurane after on-pump CABG. Sevoflurane seems to be associated with the worst cognitive outcome as assessed by neuropsychologic tests, and prolonged brain injury as detected by high S100 BP levels was seen with desflurane. © 2006 Forum Multimedia Publishing, LLC.
Yazarlar (7)
1
Meral Kanbak
2
Fatma Saricaoglu
3
Seda B. Akinci
4
Bahar Oc
ORCID: 0000-0002-2253-5191
5
Huriye Balci
6
Bilge Celebioglu
7
Ulku Aypar
Kurumlar
Hacettepe Üniversitesi
Ankara Turkey
Istanbul Üniversitesi
Istanbul Turkey
Scimago Dergi (ISSN Eşleşmesi)
Heart Surgery Forum
Q3
SJR Skoru0,237
H-Index42
YayıncıForum Multimedia Publishing LLC
ÜlkeUnited States
Surgery (Q3)
Cardiology and Cardiovascular Medicine (Q4)
Metrikler
28
Atıf
7
Yazar