Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Preoperative fibrinogen levels as a predictor of postoperative bleeding after open heart surgery
Heart Surgery Forum · Ekim 2007
YÖKSİS Kayıtları
Preoperative Fibrinogen Levels as a Predictor of Postoperative Bleeding after Open Heart Surgery
The Heart Surgery Forum · 2007 SCI-Expanded
PROFESÖR BAHAR ÖÇ →
Makale Bilgileri
DergiHeart Surgery Forum
Yayın TarihiEkim 2007
Cilt / Sayfa10 · 284-288
Scopus ID2-s2.0-35348979156
Erişim🔓 Açık Erişim
Özet
Background. Open heart surgery still involving major bleeding continues to be a major challenge after cardiac surgery and is also a significant cause of morbidity and mortality. Most hemostatic factors are intercorrelated with postoperative bleeding, and fibrinogen seems the most fundamental hemostatic risk factor for open heart surgery. Methods. The study included 97 patients who underwent elective coronary artery surgery (78 men and 19 women; mean age, 60.9 ± 10.3). Preoperative blood samples were obtained and preoprative quantitative determination of plasma fibrinogen levels were measured by the clotting method of Clauss using the fibrinogen kit. Patients were operated on by the same team and the same tecnique. The total amount of drainage blood from chest tubes was recorded after termination of operation. Results. There were statistical significance between the fibrinogen levels and the drainage (r = -0.897, P < .001). Chest drainage was a mean of 972 mL (range, 240-2445 mL) in the first 48 hours after sternotomy closure. Fibrinogen level and relation to age was statistically significant (P = .015). There was no statisticaly significance between fibrinogen levels and gender (male gender = 400.7 ± 123.0 versus female gender = 395.6 ± 148.1; P = .877) and between drainage and gender (male gender = 968.2 ± 538.5 versus female gender = 990.0 ± 554.7; P = .876). Two patients (2%) died early after the surgery. There were no significant differences between the postoperative bleeding and cardiopulmonary bypass time (P = .648) or cross-clamp time (P = .974). Conclusions. The results of this study suggested that low preoperative fibrinogen level appears to be a useful diagnostic marker to assess the activity of the coagulation system, and that its preoperative level may serve as a potential risk factor for postoperative bleeding after coronary artery bypass surgery. © 2007 Forum Multimedia Publishing, LLC.
Yazarlar (12)
1
Halil Ibrahim Ucar
2
Mehmet Oc
ORCID: 0000-0002-7832-3067
3
Mustafa Tok
4
Omer F. Dogan
5
Bahar Oc
ORCID: 0000-0002-2253-5191
6
Ahmet Aydin
7
Bora Farsak
8
Murat Guvener
9
Ali Cem Yorgancioglu
10
R. Dogan
11
Metin Demircin
12
Ilhan Pasaoglu
Kurumlar
Hacettepe Üniversitesi
Ankara Turkey
Metrikler
70
Atıf
12
Yazar