Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Long-term Survival Outcomes of Early-stage Grade 1 and 2 Endometrioid-Type Endometrial Cancer Patients
Genel Tip Dergisi · Nisan 2023
YÖKSİS Kayıtları
Erken evre grade 1 ve 2 endometrioid tip endometriyum kanseri tanılı olgularda uzun dönem sonuçları
Genel Tıp Dergisi · 2023 TR DİZİN
PROFESÖR ÇETİN ÇELİK →
Long-term Survival Outcomes of Early-stage Grade 1 and 2 EndometrioidType Endometrial Cancer Patients
Selcuk University · 2023 TR DİZİN
PROFESÖR ÇETİN ÇELİK →
Erken evre grade 1 ve 2 endometrioid tip endometriyum kanseri tanılı olgularda uzun dönem sonuçları
Genel Tıp Dergisi · 2023 TR DİZİN
DOÇENT MURAT ÇELİK →
Erken Evre Grade 1 ve 2 Endometrioid Tip Endometrium Kanseri Tanılı Olgularda Uzun Dönem Sonuçları
Genel Tıp Dergisi · 2023 TR DİZİN
PROFESÖR ORHAN ÖNDER EREN →
Erken Evre Grade 1 ve 2 Endometrioid Tip Endometrium Kanseri Tanılı Olgularda Uzun Dönem Sonuçları
Genel Tıp Dergisi · 2023 TR DİZİN
DOÇENT AHMET BİLGİ →
Long-term Survival Outcomes of Early-stage Grade 1 and 2 EndometrioidType Endometrial Cancer Patients
Selcuk University · 2023 TR DİZİN
DOÇENT HAMİT BAŞARAN →
Makale Bilgileri
DergiGenel Tip Dergisi
Yayın TarihiNisan 2023
Cilt / Sayfa33 · 232-238
Scopus ID2-s2.0-105009415882
Erişim🔓 Açık Erişim
Özet
Aim: Early-stage endometrioid-type endometrial cancer (EC) has a favorable prognosis. The recurrence is still the biggest issue. There are differences in the literature in terms of treatment modalities in the early-stage. The aim of the study is to retrospectively investigate the long-term survival outcomes of early-stage grade 1 and 2 endometrioid-type endometrial cancer patients. Methods: Out of 327 cases, 294 cases in stage 1 and 33 cases in stage 2 were evaluated. Age, stage, tumor size, histologic grade, degree of myometrial invasion, presence of lymphovascular invasion (LVSI), peritoneal cytology positive, presence of recurrence, overall survival (OS), and disease-free survival (DFS) between two groups were evaluated statistically. Results: The mean age of 327 patients was 64.0±doi.org/0 years. Out of 327, 65.7% were ≥60 years, and 90% were stage 1, 74.6% were grade 1, 1.8% had positive peritoneal cytology, 8.3% had LVSI and 86% had ≤50% myometrial invasion. Recurrence was detected in 6.4% of patients. 40.7% of patients received adjuvant radiotherapy. Only the adjuvant radiotherapy found a significant association between two groups. Only presence of recurrence in terms of OS and DFS durations was a significant parameter in the regression analysis. Conclusion: Development of recurrence in the early-stage endometrioid-type EC is the main prognostic predictor for survival. The early diagnosis and treatment of recurrence have a positive impact on the prognosis.
Yazarlar (7)
1
Fazıl Avcı
ORCID: 0000-0002-9244-9168
2
Onder Eren
ORCID: 0000-0001-6397-8207
3
A. Bilgi
ORCID: 0000-0001-8682-1739
4
Hamit Basaran
5
Murat Celik
ORCID: 0000-0002-7977-2526
6
Melek Caglayan
7
Çetin Çelik
ORCID: 0000-0001-6165-5092
Anahtar Kelimeler
Endometrial cancer
endometrioid
recurrence
survival
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey