Scopus
YÖKSİS DOI Eşleşti
SJR Q2
Molecular identification of Daedalea quercina (L.) Pers., a mushroom with antioxidant, antibacterial and anticancer functions
South African Journal of Botany · Aralık 2025
YÖKSİS Kayıtları
Molecular identification of Daedalea quercina (L.) Pers., a mushroom with antioxidant, antibacterial and anticancer functions
SOUTH AFRICAN JOURNAL OF BOTANY · 2025 SCI-Expanded
Prof. Dr. HASAN HÜSEYİN DOĞAN →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Novel perspectives on two Digitalis species: Phenolic profile, bioactivity, enzyme inhibition, and toxicological evaluation
2017 ISSN: 02546299 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Screening the in vitro antioxidant, antimicrobial, anticholinesterase, antidiabetic activities of endemic Achillea cucullata (Asteraceae) ethanol extract
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. NURANİYE ERUYGUR →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2018 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Phytochemical characterization and antioxidant activities of the fruit extracts of several Crataegus taxa
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. YÜKSEL KAN →
Gundelia rosea seed: Evaluation of biopharmaceutical potentialand bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Effect of Viscum album L. ssp. austriacum (WİESP.) Vollman on metronidazole resistant and sensitive strains of Trichomonas vaginalis
2019 ISSN: 0254-6299 SCI
Prof. Dr. NURANİYE ERUYGUR →
Effect of cold-press and soxhlet extraction on fatty acids, tocopherolsand sterol contents of the Moringa seed oils
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. MEHMET MUSA ÖZCAN →
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded Q2
Prof. Dr. GÖKHAN ZENGİN →
Enzyme inhibitory and antioxidant properties of six mushroom species from the Agaricaceae family
2019 ISSN: 02546299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
2019 ISSN: 0254-6299 SCI
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Enzyme inhibitory and antioxidant properties of six mushroom species from the Agaricaceae family
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Biopharmaceutical potential, chemical profile and in silico study of the seagrass– Syringodium isoetifolium (Asch.) Dandy
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Asphodeline cilicica Tuzlaci: From the plant to its most active part extract and its broad bioactive properties
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
In vitro plant regeneration, and jasmonic acid induced bioactive chemical accumulations in two Hypericum species from Turkey.
2020 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. ERTAN SAİT KURTAR →
Makale Bilgileri
ISSN02546299
Yayın TarihiAralık 2025
Cilt / Sayfa187 · 121-133
Scopus ID2-s2.0-105018946427
Özet
The current research work aims to identify the brown rot fungi Daedalea quercina, grown in Tunisia, using typical molecular tools, and to assess its chemical composition by UPLC-MS<sup>e</sup> analysis, antioxidant capacity using three different methods (DPPH and ABTS radical scavenging assay and FRAP) and antibacterial activity against a collection of human pathogens. The D. quercina fruiting body hydroalcoholic extract (EtOH-H<inf>2</inf>O-E) and its ethyl acetic fraction (EtOAc-F) revealed the presence of 25 secondary metabolites including triterpenes such as daedaleanic acid A, carboxyacetylquercinic acid and the 24,31-didehydro-3-(carboxyacetyloxy) quercinic acid, many of which are here reported in D. quercina for the first time. The EtOH-H<inf>2</inf>O-E of D. quercina displayed the most active DPPH and ABTS scavenging activities (598.38 and 389.20 µg/mL respectively). The antibacterial results indicated that Bacillus subtilis, a Gram-positive species, was the most sensitive to the studied extracts with low MIC values (0.03 and 0.06 mg/mL). Both extracts were proven to exhibit antitumor activity towards HeLa cells, and a protective capacity of HUVEC cells in a dose-dependent manner. The EtOH-H<inf>2</inf>O-E showed the best antitumor activity at concentrations ranging from 25 to 200 μg/ml with protection to HUVEC cells at the same concentrations. To the best of our knowledge, this represent the first chemical and pharmacological characterization of D. quercina from Tunisia, and overall one of the most exhaustive characterization of secondary metabolites in this species. Based on the encouraging obtained data, D. quercina can represent a valuable natural product with pharmaceutical and nutraceutical applications in virtue of its biological activities and its content in potential bioactive compounds.
Yazarlar (9)
1
Ameny Srih
2
Nadia Hadiji-Abbès
3
Sana Hamrouni Zahmoul
4
Rim Ladhar-Chaabouni
5
Gregorio Peron
ORCID: 0000-0002-6007-6184
6
Hasan Huseyin Dogan
7
Ursula Kües
ORCID: 0000-0001-9180-4079
8
Mohamed Trigui
9
Karama Zouari Bouassida
Anahtar Kelimeler
Antibacterial
Anticancer
Antioxidant
Daedalea quercina
Ethyl acetic fraction
HeLa cells
HUVEC cells
Hydro-alcoholic extract
UPLC-MSe
Kurumlar
Georg-August-Universität Göttingen
Gottingen Germany
Selçuk Üniversitesi
Selçuklu Turkey
Università degli Studi di Brescia
Brescia Italy
University of Sfax
Sfax Tunisia
Scimago Dergi (ISSN Eşleşmesi)
South African Journal of Botany
Q2
SJR Skoru0,558
H-Index92
YayıncıElsevier B.V.
ÜlkeNetherlands
Plant Science (Q2)
Metrikler
1
Atıf
9
Yazar
9
Anahtar Kelime