Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Exploring for HPLC-MS/MS Profiles and Biological Activities of Different Extracts from Allium lycaonicum Siehe ex Hayek from Turkey Flora
Foods · Aralık 2023
YÖKSİS Kayıtları
Exploring for HPLC-MS/MS Profiles and Biological Activities of Different Extracts from Allium lycaonicum Siehe ex Hayek from Turkey Flora
Foods · 2023 SCI-Expanded
PROFESÖR EVREN YILDIZTUGAY →
Makale Bilgileri
DergiFoods
Yayın TarihiAralık 2023
Cilt / Sayfa12
Scopus ID2-s2.0-85180712731
Erişim🔓 Açık Erişim
Özet
The present study was designed to determine the phenolic constituents, antioxidant, and enzyme inhibition activities of aerial parts and bulbs of Allium lycaonicum (family Amaryllidaceae). Extracts were prepared by maceration and Soxhlet/infusion using hexane, methanol, and water as extraction solvents. Generally, extracts from the aerial parts showed higher total phenolic and individual components and antioxidant activity than their respective bulb extracts. Maceration with water was the best to extract total phenolic content from the aerial parts (29.00 mg gallic acid equivalents (GAE)/g), while the Soxhlet extraction with hexane (22.29 mg GAE/g) was the best for the bulb. Maceration with methanol recovered the highest total flavonoid content from both the aerial parts (41.95 mg (rutin equivalents (RE)/g) and bulb (1.83 mg RE/g). Polar extracts of aerial parts were characterized by higher abundance of kaempferol-3-glucoside (≤20,624.27 µg/mg), hyperoside (≤19,722.76 µg/g), isoquercitrin (≤17,270.70 µg/g), delphindin-3,5-diglucoside (≤14,625.21 µg/g), and rutin (≤10,901.61 µg/g) than the bulb. Aerial parts’ aqueous extract, prepared by maceration, exerted the highest anti-ABTS (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical activity (64.09 mg trolox equivalents (TE)/g), Cu++ (83.03 mg TE/g) and Fe+++ (63.03 mg TE/g) reducing capacity while that prepared by infusion recorded the highest anti-DPPH (2,2-diphenyl-1-picrylhydrazyl) radical (31.70 mg TE/g) and metal chelating (27.66 mg EDTAE/g) activities. The highest total antioxidant activity (1.46 mmol TE/g) was obtained by maceration of the bulb with water. Extracts obtained by organic solvents showed remarkable enzyme inhibition properties against the tested enzymes. Soxhlet extraction of the bulb with hexane and methanol recorded the highest acetylcholinesterase inhibition (4.75 mg galanthamine equivalents (GALAE)/g) and tyrosinase inhibition (139.95 mg kojic acid equivalents/g) activities, respectively. Extracts obtained by maceration of the bulb with methanol and the aerial parts with hexane exerted the highest glucosidase inhibition (3.25 mmol acarbose equivalents/g) and butyrylcholinesterase inhibition (20.99 mg GALAE/g) activities, respectively. These data indicated that A. lycaonicum is a source of bioactive molecules with potential antioxidant and enzyme inhibition properties. Nonetheless, the extracts obtained through various solvents and extraction techniques showed variations in their phytoconstituent composition and biological properties.
Yazarlar (11)
1
Sakina Yagi
2
Nilofar
3
Gokhan Zengin
ORCID: 0000-0001-6548-7823
4
Evren Yildiztugay
ORCID: 0000-0002-4675-2027
5
Giovanni Caprioli
ORCID: 0000-0002-5530-877X
6
Diletta Piatti
ORCID: 0009-0001-9590-5560
7
Luigi Menghini
ORCID: 0000-0002-7346-7395
8
Claudio Ferrante
9
Simonetta Cristina Di Simone
ORCID: 0000-0001-5041-3848
10
Annalisa Chiavaroli
ORCID: 0000-0002-3399-967X
11
Filippo Maggi
ORCID: 0000-0003-1375-4744
Anahtar Kelimeler
Allium lycaonicum
antioxidant
enzyme inhibition
maceration
phenolic constituents
Soxhlet/infusion
Kurumlar
Khartoum University
Khartoum Sudan
Selçuk Üniversitesi
Selçuklu Turkey
Università degli Studi di Camerino
Camerino Italy
Université de Lorraine
Nancy France
University of G. d'Annunzio Chieti and Pescara
Chieti Italy
Metrikler
3
Atıf
11
Yazar
6
Anahtar Kelime