Scopus
YÖKSİS Eşleşti
Linking the chemical profile with the biological activities of Reaumuria alternifolia from Turkish flora
Journal of Molecular Structure · Şubat 2025
YÖKSİS Kayıtları
Linking the chemical profile with the biological activities of Reaumuria alternifolia from Turkish flora
Journal of Molecular Structure · 2025 SCI-Expanded
PROFESÖR EVREN YILDIZTUGAY →
Makale Bilgileri
DergiJournal of Molecular Structure
Yayın TarihiŞubat 2025
Cilt / Sayfa1321
Scopus ID2-s2.0-85203661840
Özet
The chemical composition and in vitro bioactivity of five Reaumuria alternifolia extracts obtained using solvents of different polarities (hexane, ethyl acetate, dichloromethane, methanol, and water) were investigated. LC-MSn analysis revealed the presence of phenolic acid derivatives, flavonoids, tannins, and anthocyanins as bioactive molecules in the examined plant material, the majority identified in the methanol extract. Bioactivity was evaluated in vitro through antioxidant, enzyme inhibitor, and cytotoxic assays. Extracts presented a significant biological potential, with the methanol extract being the most effective. The analyzed extracts showed that this readily available raw material is a rich source of phytonutrients, primarily antioxidant compounds. This research raises curiosity about the future perspective of Turkish Reaumuria alternifolia extracts, for the formulation of new products as nutritional supplements or improving the quality of existing products. These potential applications inspire hope for the future of natural product development and its impact on human health.
Yazarlar (8)
1
Milena Terzic
2
Stefano Dall'Acqua
3
Stefania Sut
4
Abdullahi Ibrahim Uba
5
Evren Yildiztugay
ORCID: 0000-0002-4675-2027
6
Ismail Koyuncu
7
Ozgur Yuksekdag
8
Gokhan Zengin
ORCID: 0000-0001-6548-7823
Anahtar Kelimeler
Cytotoxic activity
Enzyme inhibitor activity
Molecular docking
Phytoconstituents
Reaumuria alternifolia
Kurumlar
Harran University, Faculty of Medicine
Sanliurfa Turkey
İstanbul Arel Üniversitesi
Istanbul Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Università degli Studi di Padova
Padua Italy
University of Novi Sad
Novi Sad Serbia