Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q4
Evaluation of the hypocholesterolemic efficacy of lyophilized Nerium oleander distillate
Eurasian Journal of Veterinary Sciences · Eylül 2022
YÖKSİS Kayıtları
Evaluation of the hypocholesterolemic efficacy of lyophilized Nerium oleander distillate
Eurasian Journal of Veterinary Sciences · 2022 TR DİZİN
Dr. Öğr. Üyesi HARUN KIZILAY →
Evaluation of the hypocholesterolemic efficacy of lyophilized Nerium oleander distillate
Eurasian Journal of Veterinary Sciences · 2022 TR DİZİN
Prof. Dr. AHMET LEVENT BAŞ →
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Nerium Oleander Distilatının Antimikrobiyal Etkisinin Araştırılması
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Yerli merkeplerde vena portae’nın karaciğer içerisindeki dağılımı üzerine makroanatomik araştırmalar
2014 ISSN: 1309-6958 Cab Abstract
Prof. Dr. MUSTAFA ORHUN DAYAN →
Makale Bilgileri
ISSN13096958
Yayın TarihiEylül 2022
Cilt / Sayfa38 · 137-142
Scopus ID2-s2.0-105011270695
Erişim🔓 Açık Erişim
Özet
Aim: The purpose of this study was to assess the effect of administering Nerium oleander distillate on hypercholesterolemic rats' serum biochemical parameters. Materials and Methods: Three equal groups of 30 male Sprague-Dawley rats were formed. No application was made for the control group. The second group received a high cholesterol diet, while the third group received a high cholesterol diet in addition to lyophilized Nerium oleander distillate by oral gavage once daily. After three months, blood was drawn after sedation and they were euthanized. Serum fasting blood glucose, triglyceride, high-density lipoprotein, total cholesterol, low-density lipoprotein, alanine aminotransferase, aspartate aminotransferase, albumin, and total protein levels, as well as alkaline phosphatase, lactate dehydrogenase, creatinine, and urea levels, were determined using an autoanalyzer. Results: Alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, cholesterol, glucose, low-density lipoprotein, and triglyceride levels increased (p < 0.05) in the group fed a high cholesterol diet compared to the control group, but Nerium oleander treatment decreased the elevated aspartate aminotransferase, cholesterol, low-density lipoprotein, and triglyceride (p < 0.05). Conclusion: To summarize, it can be stated that Nerium oleander distillate has antihypercholesterolemic and liver-protective properties.
Yazarlar (3)
1
Harun Kızılay
ORCID: 0000-0003-3660-0721
2
A. L. Baş
3
Nuray Yazihan
ORCID: 0000-0003-1237-8468
Anahtar Kelimeler
hypercholesterolemia
Nerium oleander
rat
Kurumlar
Ankara Üniversitesi
Ankara Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Eurasian Journal of Veterinary Sciences
Q4
OA
SJR Skoru0,178
H-Index5
YayıncıSelcuk Universitesi, Veteriner Fakultesi
ÜlkeTurkey
Veterinary (miscellaneous) (Q4)