Scopus
YÖKSİS Eşleşti
Investigation of Causing Microorganisms and Antimicrobial Sensitivity Patterns in Diabetic Foot Wounds
Genel Tip Dergisi · Nisan 2025
YÖKSİS Kayıtları
Investigation Of Causing Microorganisms And Antimicrobial Sensitivity Patterns In Diabetic Foot Wounds
Genel Tıp Dergisi · 2025 Scopus
PROFESÖR SALİH MAÇİN →
Makale Bilgileri
DergiGenel Tip Dergisi
Yayın TarihiNisan 2025
Cilt / Sayfa35 · 276-284
Scopus ID2-s2.0-105011303802
Özet
Aim: Diabetic foot is the clinical term describing a series of diabetes-related lower extremity complications, such as ulceration, infection, and gangrene. This study aimed to prospectively investigate the causative aerobic bacteria in diabetic foot ulcer samples, as well as anaerobic bacteria and fungi, which are thought to play an important role in diabetic foot infections. Additionally, the antimicrobial susceptibility of the causative microorganisms obtained from the cultures will be investigated. Methods: Fifty-nine samples were collected from 50 patients with type 2 diabetes mellitus (DM). The BD Phoenix TM automated system was used for species-level identification of microorganisms and antimicrobial susceptibility testing. The antimicrobial susceptibility of anaerobic microorganisms was tested using the gradient test method. Results: Gram-negative aerobic bacteria were found to be the most common agents (65%) in diabetic foot infections, with 65% being multidrug-resistant. Staphylococcus aureus was identified as the most common cause of monomicrobial infections, with a methicillin-resistant rate (MRSA) of 27%. Vancomycin, teicoplanin, and linezolid were the most effective antibiotics against Gram-positive agents, while ceftolozane/tazobactam, piperacillin/tazobactam, meropenem, ertapenem, colistin, and amikacin were the most effective against Gram-negative agents. Conclusions: The high prevalence of multidrug-resistant Gram-negative agents highlights the importance of prudent antibiotic use. Considering DM is 80% preventable through lifestyle changes, increasing public awareness about healthy living is crucial.
Yazarlar (5)
1
Aynur Ismayıl
ORCID: 0000-0001-8754-5772
2
Bayram Colak
ORCID: 0009-0005-7235-5884
3
Serdar Yormaz
ORCID: 0000-0002-6273-3643
4
Hatice Türk Daği
ORCID: 0000-0002-0291-4987
5
Salih Maçin
ORCID: 0000-0002-1871-3629
Anahtar Kelimeler
Antibiotic susceptibility
diabetic foot
diabetic foot ulcer
microorganism
Kurumlar
Izmir Bakircay University
Izmir Turkey
Selçuk Tip Fakültesi
Konya Turkey