The effects of bisphenol A injected into egg yolk on skeletal muscle development in chicken

Eurasian Journal of Veterinary Sciences · Haziran 2022

YÖKSİS Kayıtları

Yumurta sarısına enjekte edilen bisfenol A' nın tavuklarda iskelet kası gelişimi üzerindeki etkileri

Eurasian Journal of Veterinary Sciences · 2022 Ebsco, WEB OF SCIENCE- ZOOLOGICAL RECORDS, CABI

PROFESÖR YASEMİN ÖZNURLU →

Yumurta sarısına enjekte edilen bisfenol A' nın tavuklarda iskelet kası gelişimi üzerindeki etkileri

Eurasian Journal of Veterinary Sciences · 2022 EBSCO, WEB OF SCIENCE- ZOOLOGICAL RECORDS

PROFESÖR TUĞBA ÖZAYDIN →

Yumurta sarısına enjekte edilen bisfenol A nın tavuklarda iskelet kası gelişimi üzerindeki etkileri

Eurasian Journal of Veterinary Sciences · 2022 EBSCO, ZOOLOGICAL RECORDS

PROFESÖR EMRAH SUR →

Makale Bilgileri

DergiEurasian Journal of Veterinary Sciences

Yayın TarihiHaziran 2022

Cilt / Sayfa38 · 90-100

DOI10.15312/EurasianJVetSci.2022.369

Scopus ID2-s2.0-105011267354

Özet Aim: The aim of this study was to determine of the effects of in ovo administered BPA on embryonic development skeletal muscle using histological methods in chickens. Materials and Methods: 310 fertile eggs of Isa Brown laying parent stock were divided into 5 groups as control, vehicle control, 50, 100, and 250 μg/egg BPA. At the 13th, 18th and 21st days of incubation, eggs were randomly opened from each group until 10 live embryos were obtained. Skeletal muscle tissue samples (musculus fibularis longus, musculus sternocoracoideus pectoralis) taken from embryos were fixed in 10% formol solution and processed with routine histological techniques and immersed in paraffin. Sections were stained with Crossmon's triple staining method. Also, PCNA (Proliferating cell nuclear antigen) reactivity was determined by immunohistochemical method. Results: Embryonic development of skeletal muscle was retarded in BPA treated groups. The mean count of PCNA positive cells significantly increased in BPA treated groups when compared to control and vehicle control groups on 21 day of incubation (p<0.05). Conclusion: These results have suggested that developmental exposure to BPA adversely affected development of skeletal muscle.