Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q4
The effect of interferon alpha administration on cytokine levels in sheep
Eurasian Journal of Veterinary Sciences · Ocak 2021
YÖKSİS Kayıtları
The effect of interferon alpha administration on cytokine levels in sheep
Eurasian Journal of Veterinary Sciences · 2020 TR DİZİN
Doç. Dr. MERVE İDER →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Serological and virological investigation of bovine viral diarrhea virus infection in cattle with abortion problem
2013 ISSN: 1309-6958 ULAKBİM-YAŞAM BİLİMLERİ
Prof. Dr. OĞUZHAN AVCI →
Antibody prevalence against respiratory viruses in naturally infected cattle in Central Anatolia
2014 ISSN: 1309-6958 ULAKBİM-YAŞAM BİLİMLERİ
Prof. Dr. OĞUZHAN AVCI →
Disseminated metastatic transmissible venereal tumour in a bitch
2013 ISSN: 1309-6958 TR DİZİN 1 atıf
Prof. Dr. MEHMET MADEN →
Investigation on Listeria spp. in Patrige Meat
2014 ISSN: 1309-6958 ULAKBİM TR DİZİN, CAB Abstracts, Index Copernicus
Prof. Dr. GÜRKAN UÇAR →
Pastörize sıvı yumurta ile kabuklu yumurtanın bazı kalite özellikleri bakımından kıyaslanması
2015 ISSN: 1309-6958 ULAKBİM TR DİZİN, CAB Abstracts, Index Copernicus
Prof. Dr. AHMET GÜNER →
Barınak Köpeklerinde Canine Coronavirus Varlığının Belirlenmesi
2015 ISSN: 1309-6958 TR DİZİN
Doç. Dr. IRMAK DİK →
Microbiological quality of red meat pieces
2015 ISSN: 1309-6958 Türkiye Atıf Dizini *EBSCO-HOST*Cab Abstracts*Veterinary Bulletin*Veterinary Science Database*Index Veterinarius*Dairy Science Abstracts *Animal Breeding Abstracts*Agricultural Engineering Abstracts *Global Health*World Agricultural Economics and Rural Sociology Abstracts *Forest Products Abstracts
Prof. Dr. ÜMİT GÜRBÜZ →
Nerium Oleander Distilatının Antimikrobiyal Etkisinin Araştırılması
2013 ISSN: 1309-6958 TR DİZİN
Prof. Dr. BURAK DİK →
Doksorubisinin neden olduğu organ hasarlarında Nerium Oleander distilatının koruyucu etkinliğinin belirlenmesi
2014 ISSN: 1309-6958 TR DİZİN
Prof. Dr. BURAK DİK →
Koyunlarda Tarantula cubensis alkolik ekstraktının (Theranekron) serum tiyobarbitürik asit reaktif ürünlerine etkisi
2014 ISSN: 1309-6958 TR DİZİN
Prof. Dr. BURAK DİK →
Pathological and microbiological investigations on the lesions of the respiratory systems of laying hens
2008 ISSN: 1309-6958 *TÜBİTAK-ULAKBİM-YAŞAM BİLİMLERİ *Türkiye Atıf Dizini *EBSCO-HOST *Cab Abstracts *Veterinary Bulletin *Veterinary Science Database *Index Veterinarius *Dairy Science Abstracts *Animal Breeding Abstracts *Agricultural Engineering Abstracts *Global Health *World Agricultural Economics and Rural Sociology Abstracts *Forest Products Abstracts *Grasslands and Forage Abstracts *Helminthological Abstracts *Rural Development Abstracts *Soils and Fertilizers *Soybean Abstracts *Sugar Industry Abstracts *Tropical Disaeases Bulletin *Wheat, Barley and Tritacale Abstracts *Maize Abstracts
Prof. Dr. ÖZGÜR ÖZDEMİR →
The retrospective evaluations of the neoplastic cases of dog between 2006 to 2011
2013 ISSN: 1309-6958 *TÜBİTAK-ULAKBİM-YAŞAM BİLİMLERİ*Türkiye Atıf Dizini*EBSCO-HOST*Cab Abstracts*Veterinary Bulletin*Veterinary Science Database*Index Veterinarius*Dairy Science Abstracts*Animal Breeding Abstracts*Agricultural Engineering Abstracts*Global Health*World Agricultural Economics and Rural Sociology Abstracts*Forest Products Abstracts*Grasslands and Forage Abstracts*Helminthological Abstracts*Rural Development Abstracts*Soils and Fertilizers*Soybean Abstracts*Sugar Industry Abstracts*Tropical Disaeases Bulletin*Wheat, Barley and Tritacale Abstracts*Maize Abstracts
Prof. Dr. ÖZGÜR ÖZDEMİR →
Bir İnekte Melanom Olgusu
2006 ISSN: 1309-6958 *TÜBİTAK-ULAKBİM-YAŞAM BİLİMLERİ*Türkiye Atıf Dizini*EBSCO-HOST*Cab Abstracts*Veterinary Bulletin*Veterinary Science Database*Index Veterinarius*Dairy Science Abstracts*Animal Breeding Abstracts*Agricultural Engineering Abstracts*Global Health*World Agricultural Economics and Rural Sociology Abstracts*Forest Products Abstracts*Grasslands and Forage Abstracts*Helminthological Abstracts*Rural Development Abstracts*Soils and Fertilizers*Soybean Abstracts*Sugar Industry Abstracts*Tropical Disaeases Bulletin*Wheat, Barley and Tritacale Abstracts*Maize Abstracts
Prof. Dr. ÖZGÜR ÖZDEMİR →
Ham ayçiçek yağı yerine yan ürünlerinin yumurta tavuklarında enerji kaynağı olarak kullanımı
1994 ISSN: 1309 - 6958 TR DİZİN
Prof. Dr. TAHİR BALEVİ →
Serbest ve korunmuş formdaki asit yağın süt ineklerinde rumen fermentasyonu ve süt verimi üzerine etkileri
2000 ISSN: 1309 - 6958 TR DİZİN
Prof. Dr. HUZUR DERYA ARIK →
Geçiş dönemindeki süt ineklerinde gliserol kullanımının etkileri
2010 ISSN: 1309 - 6958 TR DİZİN
Prof. Dr. TAHİR BALEVİ →
Bazı et ürünlerinde E coli O157 H7 varlığının araştırılması
2010 ISSN: 1309-6958 EBSCO-HOST*Cab Abstracts*Veterinary Bulletin*Veterinary Science Database*Index Veterinarius 1 atıf
Prof. Dr. ÜMİT GÜRBÜZ →
Karaman ilinde yetiştirilen koyunlarda Blue Tongue Virus enfeksiyonunun serolojik olarak araştırılması
2015 ISSN: 1309-6958 TÜBİTAK Yaşam Bilimleri, CAB Abstracts, Vet Bull, EBSCO, Vet Sci Database vs...
Prof. Dr. ATİLLA ŞİMŞEK →
Yerli merkeplerde vena portae’nın karaciğer içerisindeki dağılımı üzerine makroanatomik araştırmalar
2014 ISSN: 1309-6958 Cab Abstract
Prof. Dr. MUSTAFA ORHUN DAYAN →
Makale Bilgileri
ISSN13096958
Yayın TarihiOcak 2021
Cilt / Sayfa36 · 324-330
Scopus ID2-s2.0-105011257927
Erişim🔓 Açık Erişim
Özet
Aim: The primary aim of this study was to determine the effect of parenteral recombinant human interferon (rHuIFN)-α2a administration on serum tumor necrosis factor (TNF)-α, interleukin (IL)-6 and IL-10 levels in healthy sheep. In addition, the main physiological parameters (rectal temperature, pulse rate, respiratory rate), hemogram and blood gas parameters were determined, as well. Materials and Methods: In this study, 9.000.000 IU rHuIFN-α2a was administered subcutaneously in 10 Merinos sheep. Blood samples were taken before (0 hours) and after at 4, 8, 12, 24, 48, 72, 96 and 120 hours. Rectal temperature, pulse and respiratory rate were also determined at the same sampling times. Sheep-specific TNF-α, IL-6 and IL-10 levels were determined from serum samples by the ELISA reader. Hemogram and blood gas parameters were measured by complete blood cell counter and blood gas analyzer, respectively. Results: After rHuIFN-α2a treatment, TNF-α and IL-10 concentrations reached peak levels (p<0.05) at the 96 hours, whereas the IL-6 level did not change in a statistically significant (p>0.05). On the other hand, a temporary increase in rectal temperature and pO2 levels (p<0.05) were determined, while decreased potassium and ionized calcium levels (p<0.05) were measured. Statistically significantly (p<0.05) fluctuations were determined in pulse rate, white blood cell counts, pH, base(ecf) and sodium values. Conclusion: It may be stated that administration of rHuIFN-α2a showed immunological effects in sheep, as it is generally accepted as safe and can be considered for use in treatment.
Yazarlar (5)
1
Devran Coskun
ORCID: 0000-0003-1151-1861
2
Merve Ider
ORCID: 0000-0003-2928-5452
3
Mustafa Sedat Arslan
ORCID: 0000-0002-4079-500X
4
Rahmi Canbar
ORCID: 0000-0001-7100-4437
5
E. Yazar
Anahtar Kelimeler
Blood gases
Cytokines
Hemogram
Interferon
Sheep
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Siirt Üniversitesi
Siirt Turkey
Scimago Dergi (ISSN Eşleşmesi)
Eurasian Journal of Veterinary Sciences
Q4
OA
SJR Skoru0,178
H-Index5
YayıncıSelcuk Universitesi, Veteriner Fakultesi
ÜlkeTurkey
Veterinary (miscellaneous) (Q4)