Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q4
Determination of embryotoxic dose limit of detomidine with in-ovo model
Eurasian Journal of Veterinary Sciences · Ocak 2021
YÖKSİS Kayıtları
Detomidinin embriyotoksik doz sınırının in-ovo model ile belirlenmesi
Eurasian Journal of Veterinary Sciences · 2021 TR DİZİN
Prof. Dr. ENVER YAZAR →
Detomidinin embriyotoksik doz sınırının in-ovo model ile belirlenmesi
Eurasian Journal of Veterinary Sciences · 2021 ebsco
Prof. Dr. ENVER YAZAR →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Serological and virological investigation of bovine viral diarrhea virus infection in cattle with abortion problem
2013 ISSN: 1309-6958 ULAKBİM-YAŞAM BİLİMLERİ
Prof. Dr. OĞUZHAN AVCI →
Antibody prevalence against respiratory viruses in naturally infected cattle in Central Anatolia
2014 ISSN: 1309-6958 ULAKBİM-YAŞAM BİLİMLERİ
Prof. Dr. OĞUZHAN AVCI →
Disseminated metastatic transmissible venereal tumour in a bitch
2013 ISSN: 1309-6958 TR DİZİN 1 atıf
Prof. Dr. MEHMET MADEN →
Investigation on Listeria spp. in Patrige Meat
2014 ISSN: 1309-6958 ULAKBİM TR DİZİN, CAB Abstracts, Index Copernicus
Prof. Dr. GÜRKAN UÇAR →
Pastörize sıvı yumurta ile kabuklu yumurtanın bazı kalite özellikleri bakımından kıyaslanması
2015 ISSN: 1309-6958 ULAKBİM TR DİZİN, CAB Abstracts, Index Copernicus
Prof. Dr. AHMET GÜNER →
Barınak Köpeklerinde Canine Coronavirus Varlığının Belirlenmesi
2015 ISSN: 1309-6958 TR DİZİN
Doç. Dr. IRMAK DİK →
Microbiological quality of red meat pieces
2015 ISSN: 1309-6958 Türkiye Atıf Dizini *EBSCO-HOST*Cab Abstracts*Veterinary Bulletin*Veterinary Science Database*Index Veterinarius*Dairy Science Abstracts *Animal Breeding Abstracts*Agricultural Engineering Abstracts *Global Health*World Agricultural Economics and Rural Sociology Abstracts *Forest Products Abstracts
Prof. Dr. ÜMİT GÜRBÜZ →
Nerium Oleander Distilatının Antimikrobiyal Etkisinin Araştırılması
2013 ISSN: 1309-6958 TR DİZİN
Prof. Dr. BURAK DİK →
Doksorubisinin neden olduğu organ hasarlarında Nerium Oleander distilatının koruyucu etkinliğinin belirlenmesi
2014 ISSN: 1309-6958 TR DİZİN
Prof. Dr. BURAK DİK →
Koyunlarda Tarantula cubensis alkolik ekstraktının (Theranekron) serum tiyobarbitürik asit reaktif ürünlerine etkisi
2014 ISSN: 1309-6958 TR DİZİN
Prof. Dr. BURAK DİK →
Pathological and microbiological investigations on the lesions of the respiratory systems of laying hens
2008 ISSN: 1309-6958 *TÜBİTAK-ULAKBİM-YAŞAM BİLİMLERİ *Türkiye Atıf Dizini *EBSCO-HOST *Cab Abstracts *Veterinary Bulletin *Veterinary Science Database *Index Veterinarius *Dairy Science Abstracts *Animal Breeding Abstracts *Agricultural Engineering Abstracts *Global Health *World Agricultural Economics and Rural Sociology Abstracts *Forest Products Abstracts *Grasslands and Forage Abstracts *Helminthological Abstracts *Rural Development Abstracts *Soils and Fertilizers *Soybean Abstracts *Sugar Industry Abstracts *Tropical Disaeases Bulletin *Wheat, Barley and Tritacale Abstracts *Maize Abstracts
Prof. Dr. ÖZGÜR ÖZDEMİR →
The retrospective evaluations of the neoplastic cases of dog between 2006 to 2011
2013 ISSN: 1309-6958 *TÜBİTAK-ULAKBİM-YAŞAM BİLİMLERİ*Türkiye Atıf Dizini*EBSCO-HOST*Cab Abstracts*Veterinary Bulletin*Veterinary Science Database*Index Veterinarius*Dairy Science Abstracts*Animal Breeding Abstracts*Agricultural Engineering Abstracts*Global Health*World Agricultural Economics and Rural Sociology Abstracts*Forest Products Abstracts*Grasslands and Forage Abstracts*Helminthological Abstracts*Rural Development Abstracts*Soils and Fertilizers*Soybean Abstracts*Sugar Industry Abstracts*Tropical Disaeases Bulletin*Wheat, Barley and Tritacale Abstracts*Maize Abstracts
Prof. Dr. ÖZGÜR ÖZDEMİR →
Bir İnekte Melanom Olgusu
2006 ISSN: 1309-6958 *TÜBİTAK-ULAKBİM-YAŞAM BİLİMLERİ*Türkiye Atıf Dizini*EBSCO-HOST*Cab Abstracts*Veterinary Bulletin*Veterinary Science Database*Index Veterinarius*Dairy Science Abstracts*Animal Breeding Abstracts*Agricultural Engineering Abstracts*Global Health*World Agricultural Economics and Rural Sociology Abstracts*Forest Products Abstracts*Grasslands and Forage Abstracts*Helminthological Abstracts*Rural Development Abstracts*Soils and Fertilizers*Soybean Abstracts*Sugar Industry Abstracts*Tropical Disaeases Bulletin*Wheat, Barley and Tritacale Abstracts*Maize Abstracts
Prof. Dr. ÖZGÜR ÖZDEMİR →
Ham ayçiçek yağı yerine yan ürünlerinin yumurta tavuklarında enerji kaynağı olarak kullanımı
1994 ISSN: 1309 - 6958 TR DİZİN
Prof. Dr. TAHİR BALEVİ →
Serbest ve korunmuş formdaki asit yağın süt ineklerinde rumen fermentasyonu ve süt verimi üzerine etkileri
2000 ISSN: 1309 - 6958 TR DİZİN
Prof. Dr. HUZUR DERYA ARIK →
Geçiş dönemindeki süt ineklerinde gliserol kullanımının etkileri
2010 ISSN: 1309 - 6958 TR DİZİN
Prof. Dr. TAHİR BALEVİ →
Bazı et ürünlerinde E coli O157 H7 varlığının araştırılması
2010 ISSN: 1309-6958 EBSCO-HOST*Cab Abstracts*Veterinary Bulletin*Veterinary Science Database*Index Veterinarius 1 atıf
Prof. Dr. ÜMİT GÜRBÜZ →
Karaman ilinde yetiştirilen koyunlarda Blue Tongue Virus enfeksiyonunun serolojik olarak araştırılması
2015 ISSN: 1309-6958 TÜBİTAK Yaşam Bilimleri, CAB Abstracts, Vet Bull, EBSCO, Vet Sci Database vs...
Prof. Dr. ATİLLA ŞİMŞEK →
Yerli merkeplerde vena portae’nın karaciğer içerisindeki dağılımı üzerine makroanatomik araştırmalar
2014 ISSN: 1309-6958 Cab Abstract
Prof. Dr. MUSTAFA ORHUN DAYAN →
Makale Bilgileri
ISSN13096958
Yayın TarihiOcak 2021
Cilt / Sayfa37 · 71-75
Scopus ID2-s2.0-105011261557
Erişim🔓 Açık Erişim
Özet
Aim: The aim of this study is to determine the embryotoxic dose limit of detomidine with an in-ovo model using fertile hen's eggs. Materials and Methods: 210 fertile eggs were divided into 7 equal (n: 30) groups and placed in the incubator under optimum conditions. No application was made to the first group. On the seventh day, normal saline solution, 10, 5, 2.5, 1.25, and 0.625 mg/kg doses of detomidine were administered to egg air-sacs in the other groups, respectively. On the 21st day, the eggs were opened and malformations, dead embryos and non-fertile eggs were determined. Results: While 3, 2, 4, 6 and 5 dead embryos were determined in 0.625, 1.25, 2.5, 5, and 10 mg/kg treated groups, respectively, no dead embryos were observed in the control and saline groups. While one non-fertile egg was determined in the control and 5 mg/kg detomidine groups, no nonfertile eggs were observed in the other groups. Mortality rates of detomidine group at doses of 2.5, 5 and 10 mg/kg were higher than the control and saline groups (p<0.05). Conclusion: Considering that the used smallest dose is 7.8 times higher than the highest recommended dose for the target species, recommended dose can be accepted safe in pregnant mammals for embryonic death. However, considering that the dose should be 100 times lower as a safety factor for mammals, it should be taken into account that negativities may also be observed.
Yazarlar (4)
1
Rahmi Canbar
ORCID: 0000-0001-7100-4437
2
Muhittin Uslu
ORCID: 0000-0002-9027-4229
3
Oznur Tufan
4
E. Yazar
Anahtar Kelimeler
Detomidine
Embryotoxicity
In-ovo model
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Eurasian Journal of Veterinary Sciences
Q4
OA
SJR Skoru0,178
H-Index5
YayıncıSelcuk Universitesi, Veteriner Fakultesi
ÜlkeTurkey
Veterinary (miscellaneous) (Q4)
Metrikler
5
Atıf
4
Yazar
3
Anahtar Kelime