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Fatigue Is Common and Predicted by Female Gender and Sleep Disturbance in Patients with Chronic Spontaneous Urticaria

Journal of Allergy and Clinical Immunology in Practice · Ocak 2021

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YÖKSİS Kayıtları
Fatigue is Common and Predicted by Female Gender and Sleep Disturbance in Patients with Chronic Spontaneous Urticaria
Journal of Allergy and Clinical Immunology-In Practice · 2021 SCI-Expanded
DOÇENT KEMAL EROL →

Makale Bilgileri

DergiJournal of Allergy and Clinical Immunology in Practice
Yayın TarihiOcak 2021
Cilt / Sayfa9 · 469-476
Özet Background: Fatigue is a common and disabling symptom in chronic inflammatory diseases. To the best of our knowledge, there are no studies evaluating fatigue thoroughly in patients with chronic spontaneous urticaria (CSU). Objectives: To evaluate fatigue and its drivers in patients with CSU, and to compare patients with healthy controls in terms of fatigue. Methods: One hundred and three patients with CSU and 35 age- and gender-matched healthy control subjects were evaluated for fatigue with the Fatigue Severity Scale (FSS) and visual analog scale-fatigue. Patients were also assessed for their duration, activity, and control of disease, as well as anxiety, depression, and quality of life (QoL). Results: There were no significant associations between disease activity, disease control scores, and FSS (P >.05). Although there were no significant differences in terms of antinuclear antibody positivity and IgE levels between fatigued and nonfatigued patients with CSU, C-reactive protein levels were higher in fatigued patients (P =.009). A significant correlation was noted between total FSS score and both Chronic Urticaria-QoL (r = 0.246, P =.013) and Dermatology Life Quality Index (r = 0.302, P =.002) in patients with CSU. In regression analyses, female gender and the presence of disturbed sleep were found to be significant predictors of fatigue in patients with CSU (P =.008; odds ratio [OR]: 9.02, and P =.001; OR: 8.35). Conclusion: Fatigue is a common and important symptom in patients with CSU and adversely affects QoL. While evaluating patients with CSU, it is important to assess fatigue, especially in female gender patients and in those having sleep disturbance.

Yazarlar (3)

1
Kemal Erol
ORCID: 0000-0003-0673-3961
2
Şule Ketenci Ertaş
3
Ragıp Ertaş

Anahtar Kelimeler

Chronic spontaneous urticaria Fatigue Quality of life

Kurumlar

Kayseri City Hospital
Kayseri Turkey

Metrikler

19
Atıf
3
Yazar
3
Anahtar Kelime

Sistemimizdeki Yazarlar