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The Efficacy of Preemptive Pregabalin Administration on Pre-and Postoperative Anxiety and Postoperative Analgesia in Arthroscopic Shoulder Surgery: A Prospective, Randomızed Double-Blind, Placebo-Controlled Clinical Study

Genel Tip Dergisi · Şubat 2022

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YÖKSİS Kayıtları
The Efficacy Of Preemptive Pregabalİn Administration on Pre-and Postoperative Anxiety and Postoperative Analgesia in Arthroscopic Shoulder Surgery: A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Study
GENEL TIP DERGİSİ · 2022 ALAN ENDEXLERİ
PROFESÖR FARUK ÇİÇEKCİ →
The Efficacy of Preemptive Pregabalin Administration on Pre- and Postoperative Anxiety and Postoperative Analgesia in Arthroscopic Shoulder Surgery: A Prospective, randomized Double-Blind, Placebo-Controlled Clinical Study
Genel Tıp · 2022 TR DİZİN
PROFESÖR İNCİ KARA →
THE EFFICACY OF PREEMPTIVE PREGABALİN ADMINISTRATION ON PRE- AND POSTOPERATIVE ANXIETY AND POSTOPERATIVE ANALGESIA IN ARTHROSCOPIC SHOULDER SURGERY: A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL STUDY
Selcuk University · 2022 EBSCOHost
PROFESÖR MEHMET SARGIN →
THE EFFICACY OF PREEMPTIVE PREGABALİN ADMINISTRATION ON PRE- AND POSTOPERATIVE ANXIETY AND POSTOPERATIVE ANALGESIA IN ARTHROSCOPIC SHOULDER SURGERY: A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL STUDY
Genel Tıp Dergisi · 2022 TR DİZİN
DOKTOR ÖĞRETİM ÜYESİ MUSLU KAZIM KÖREZ →

Makale Bilgileri

DergiGenel Tip Dergisi
Yayın TarihiŞubat 2022
Cilt / Sayfa32 · 12-18
Özet Aim: Few studies have investigated pregabalin use as preemptive analgesia in the management of acute pain and anxiety following arthroscopic shoulder surgery. We hypothesized that the preemptive use of oral pregabalin might decrease pain and postoperative anxiety on arthroscopic shoulder surgery pain during the initial 48 hours. Patients and methods: In this prospective, randomized, double-blind, placebo-controlled study, 65 eligible patients were randomly divided into two groups, the preemptive pregabalin 150 mg (group P) and the control group (group C). The primary outcomes were pain levels measured both rest and during active motion based on a visual analog scale (VAS). Secondary outcomes were the level of anxiety (STAI-S and STAI-T), patient satisfaction, and complications. Results: Group P showed lower pain (p < 0.001), lower opioid consumption (p < 0.001), longer time to first requirement of analgesia (p < 0.001), and lower rescue analgesic dose (p < 0.001) than the control group at postoperative 48 h follow-up. Also, group P showed less preoperative and postoperative anxiety (p < 0.001) and greater patient satisfaction (p < 0.001) than group C. The rate of postoperative adverse effects was similar between the groups (p > 0.05). Conclusion: The preemptive use of oral pregabalin received 150 mg daily for 2 days before surgery provided postoperative analgesia in both rest and active motion, and improved preoperative and postoperative anxiety levels and greater patient satisfaction in patients undergoing arthroscopic surgery.

Yazarlar (6)

1
Faruk Cicekci
2
Mehmet Sargin
3
Ahmet Yıldırım
4
M. K. Korez
ORCID: 0000-0001-9524-6115
5
Göksun Günaydin
ORCID: 0000-0002-8989-6186
6
Inci Kara

Anahtar Kelimeler

analgesia anxiety orthopedic surgery preemptive pregabalin

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

1
Atıf
6
Yazar
5
Anahtar Kelime

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