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Olfactory dysfunction in primary sjogren’s syndrome and its correlation with dry eye

Acta Otorhinolaryngologica Italica · Ekim 2021

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YÖKSİS Kayıtları
Olfactory dysfunction in primary Sjogren's syndrome and its correlation with dry eye
Acta Otorhinolaryngologica Italica · 2021 SCI-Expanded
DOÇENT ÇAĞDAŞ ELSÜRER →
Olfactory dysfunction in primary Sjogren's syndrome and its correlation with dry eye
Acta Otorhinolaryngologica Italica · 2021 SCI-Expanded
PROFESÖR SEMA YILMAZ →
Olfactory dysfunction in primary Sjogren's syndrome and its correlation with dry eye
Acta Otorhinolaryngologica Italica · 2021 SCI-Expanded
PROFESÖR METE KAAN BOZKURT →
Olfactory dysfunction in primary Sjogren\u2019s syndrome and its correlation with dry eye
Acta Otorhinolaryngologica Italica · 2021 SCI-Expanded
PROFESÖR BANU BOZKURT →

Makale Bilgileri

DergiActa Otorhinolaryngologica Italica
Yayın TarihiEkim 2021
Cilt / Sayfa41 · 443-449
Erişim🔓 Açık Erişim
Özet SUMMARY Objective. To evaluate the olfactory function in primary Sjögren’s syndrome (pSS) patients and investigate its correlation with dry eye parameters. Methods. Thirty-eight pSS patients (49.47 ± 10.06 years) and 20 healthy volunteers (47.40 ± 8.92 years) were enrolled in the study. All participants underwent ENT and eye examinations including a modified Connecticut Chemosensory Clinical Research Center (CCCRC) test, tear break-up time (TBUT), ocular surface staining (OSS) and Schirmer test. The parameters were compared between the two groups using Student-t test, and Pearson test was used to evaluate the correlations. Results. Mean Schirmer and TBUT values were 2.39 ± 1.48 mm/5 min and 3.66 ± 1.5 sec in pSS and 18.30 ± 6.16 mm/5 min and 14.60 ± 3.64 sec in healthy subjects (p < 0.001, both). There was a significant decrease in mean odour threshold, odour identification, CC-CRC and VAS scores in the pSS group (p < 0.001). Dry eye parameters showed moderate correlations with CCCRC parameters (r = 0.4-0.6, p < 0.001) and olfaction VAS score (r = 0.4-0.75, p < 0.05). Conclusions. There is a mild clinical impairment in smell sense in patients with pSS which seems to be correlated with dry eye parameters. Therefore, smell complaints should be queried in pSS patients suffering from severe dry eye.

Yazarlar (6)

1
Yunus E. Topan
2
Banu Bozkurt
ORCID: 0000-0002-9847-3521
3
Sema Yılmaz
ORCID: 0000-0003-4277-3880
4
Çağdaş Elsürer
ORCID: 0000-0001-9804-7023
5
Sona Gorcuyeva
6
Mete Kaan Bozkurt
ORCID: 0000-0002-3153-3294

Anahtar Kelimeler

CCCRC Dry eye Olfactory dysfunction Primary Sjögren’s syndrome

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

6
Atıf
6
Yazar
4
Anahtar Kelime

Sistemimizdeki Yazarlar