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Red Blood Cell Distribution width: A Reliable Marker in Patients with Multiple Sclerosis?

Genel Tip Dergisi · Aralık 2024

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YÖKSİS Kayıtları
Red blood cell distribution width (RDW) is a reliable marker in patients with multiple sclerosis
Genel Tıp Dergisi · 2024 TR DİZİN
DOÇENT FETTAH EREN →
Red blood cell distribution width (RDW) is a reliable marker in patients with multiple sclerosis
Genel Tıp Dergisi · 2024 TR DİZİN
PROFESÖR HALUK GÜMÜŞ →
Red blood cell distribution width (RDW) is a reliable marker in patients with multiple sclerosis
Genel Tıp Dergisi · 2024 TR DİZİN
PROFESÖR GÖKHAN ÖZDEMİR →

Makale Bilgileri

DergiGenel Tip Dergisi
Yayın TarihiAralık 2024
Cilt / Sayfa34 · 750-754
DOI10.54005/geneltip.1409331
Scopus ID2-s2.0-105009907211
Özet Objective: The red blood cell distribution width (RDW) is a prognostic marker in patients with active or chronic inflammation, cardiovascular and the other autoimmune diseases. Our aim of this study is to evaluate levels of the RDW in patients with multiple sclerosis, disease subtypes and attacked groups. Material and Methods: Multiple sclerosis (MS) patients and healthy individuals were included in the study. Demographic characteristics of MS and control group, types of MS, MS attacks or no attack, and laboratory parameters analysis was evaluated. The RDW was calculated according to the formula: RDW = (Coefficient of Variability of RBC ÷ mean MCV) × 100. All groups and subgroups were compered according to RDW-value. Results: The study was conducted 105 MS patients, 74 (70.5%) females and 31 (29.5%) males, with a mean age of 38 (20-64) years. RDW values in the MS group were 13.8 (12.1-27.1), whereas in the control group the values were 13.4 (12.1-17.4) (p=0.007). ROC analysis revealed that using a cut-off point of 13.55, RDW predicts MS with a sensitivity of 59% and specificity of 54.2%. There was no statistically significant difference among the MS subgroups and attacked groups according to RDW value (p=0.41, p=0.92).

Yazarlar (4)

1
Gokhan Ozdemir
ORCID: 0000-0001-8140-6333
2
Fettah Eren
3
Cihat Özgüncü
4
Haluk Gümüş
ORCID: 0000-0001-7689-7131

Anahtar Kelimeler

Biomarker Inflammatio Multiple sclerosis Red blood cell distribution width

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey
University of Health Sciences
Istanbul Turkey

Sistemimizdeki Yazarlar

GÖ
GÖKHAN ÖZDEMİR
PROFESÖR

Hızlı Erişim

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