Scopus
YÖKSİS DOI Eşleşti
SJR Q2
Use of intestine-related biomarkers for detecting intestinal epithelial damage in neonatal calves with diarrhea
American Journal of Veterinary Research · Şubat 2020
YÖKSİS Kayıtları
Use of intestine-related biomarkers for detecting intestinal epithelial damage in neonatal calves with diarrhea
AMERICAN JOURNAL OF VETERINARY RESEARCH · 2020 SCI-Expanded
Prof. Dr. FATİH HATİPOĞLU →
Use of intestine-related biomarkers for detecting intestinal epithelial damage in neonatal calves with diarrhea
American Journal of Veterinary Research · 2020 SCI-Expanded
Prof. Dr. KAMİL ÜNEY →
Use of intestine-related biomarkers for detecting intestinal epithelial damage in neonatal calves with diarrhea
American Journal of Veterinary Research · 2020 SCI-Expanded
Prof. Dr. NURİ BAŞPINAR →
Use of intestine-related biomarkers for detecting intestinal epithelial damage in neonatal calves with diarrhea
American Journal of Veterinary Research · 2020 SCI-Expanded
Doç. Dr. MERVE İDER →
Use of intestine-related biomarkers for detecting intestinal epithelial damage in neonatal calves with diarrhea
American Journal of Veterinary Research · 2020 SCI-Expanded
Prof. Dr. MAHMUT OK →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Pharmacokinetics of meloxicam in red eared slider turtles Trachemys scripta elegans after single intravenous and intramuscular injections
2016 ISSN: 0002-9645 SCI-Expanded
Prof. Dr. KAMİL ÜNEY →
Pharmacokinetics of meloxicam in red eared slider turtles Trachemys scripta elegans after single intravenous and intramuscular injections
2016 ISSN: 0002-9645 SCI
Prof. Dr. BURAK DİK →
Pharmacokinetics of pentoxifylline and its 5-hydroxyhexyl metabolite after intravenous administration of increasing doses to sheep
2019 ISSN: 0002-9645 SCI
Prof. Dr. KAMİL ÜNEY →
Use of intestine-related biomarkers for detecting intestinal epithelial damage in neonatal calves with diarrhea
2020 ISSN: 0002-9645 SCI-Expanded
Prof. Dr. FATİH HATİPOĞLU →
Pharmacokinetics of pentoxifylline and its 5-hydroxyhexyl metabolite after intravenous administration of increasing doses to sheep
2019 ISSN: 0002-9645 SCI-Expanded
Prof. Dr. AYŞE ER →
Use of intestine-related biomarkers for detecting intestinal epithelial damage in neonatal calves with diarrhea
2020 ISSN: 0002-9645 SCI-Expanded Q3
Prof. Dr. MAHMUT OK →
Use of intestine-related biomarkers for detecting intestinal epithelial damage in neonatal calves with diarrhea
2020 ISSN: 0002-9645 SCI-Expanded
Prof. Dr. NURİ BAŞPINAR →
Histologic characteristics and local cellular immunity of the gland of the third eyelid after topical ophthalmic administration of 2 cyclosporine for treatment of dogs with keratoconjunctivitis sicca
2002 ISSN: 0002-9645 SSCI
Prof. Dr. İLHAMİ ÇELİK →
Biomarkers of infectious pneumonia in naturally infected calves
2022 ISSN: 0002-9645 SCI-Expanded Q3
Prof. Dr. MEHMET MADEN →
Histological Characteristics and Lokal Cellular Immunity of the Gland of the Third Eyelid After Topical Ophthalmic Administration of 2% Cyclosporine for Treatment of Dogs with Keratoconjunctivitis sicca
2002 ISSN: 0002-9645 SCI-Expanded
Prof. Dr. FAHRETTİN ALKAN →
Makale Bilgileri
ISSN00029645
Yayın TarihiŞubat 2020
Cilt / Sayfa81 · 139-146
Scopus ID2-s2.0-85078331028
Özet
OBJECTIVE To evaluate the usefulness of intestinal biomarkers in determining the presence of intestinal epithelial damage in neonatal calves with diarrhea caused by 4 etiologic agents. ANIMALS 40 neonatal calves that were healthy (n = 10) or had diarrhea (30). PROCEDURES The study was a cross-sectional study. Results of hematologic analyses and serum concentrations of intestinal fatty acid–binding protein (I-FABP), liver fatty acid–binding protein (L-FABP), trefoil factor 3 (TFF-3), Claudin-3 (CLDN-3), γ-enteric smooth muscle actin (ACTG2), intestinal alkaline phosphatase (IAP), interleukin-8 (IL-8), platelet-activating factor (PAF), and leptin (LP) were compared among calves grouped according to whether they were healthy (control group; G-1) or had diarrhea caused by K99 Escherichia coli (G-2; n = 10), bovine rota-or coronavirus (G-3; 5 each), or Cryptosporidium spp (G-4; 10). RESULTS Across the 3 time points at which blood samples were obtained and evaluated, the groups of calves with diarrhea generally had markedly higher mean serum concentrations of L-FABP, TFF-3, IAP, IL-8, and LP, compared with the control group. In addition, G-2 also consistently had markedly higher mean serum concentrations of I-FAB and ACTG2 and lower mean serum concentrations of CLDN-3, compared with the control group. CONCLUSIONS AND CLINICAL RELEVANCE Results indicated that degree of intestinal epithelial damage differed among calves grouped by the etiologic agent of diarrhea and that such damage might have been more severe in calves with diarrhea caused by K99 E coli. Additionally, our results indicated that serum concentrations of I-FABP, L-FABP, TFF-3, IAP, IL-8, ACTG2, LP, and CLDN-3 were useful biomarkers of intestinal epithelial damage in calves of the present study.
Yazarlar (9)
1
M. Ok
2
Ramazan Yildiz
3
Fatih Hatipoglu
4
N. Baspinar
5
Merve Ider
ORCID: 0000-0003-2928-5452
6
Kamil Üney
ORCID: 0000-0002-8674-4873
7
Alper Erturk
8
Murat Kaan Durgut
9
Funda Terzi
ORCID: 0000-0002-6184-5408
Kurumlar
Burdur Mehmet Akif Ersoy Üniversitesi
Burdur Turkey
Kastamonu University
Kastamonu Turkey
Mustafa Kemal Üniversitesi
Antakya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
American Journal of Veterinary Research
Q2
OA
SJR Skoru0,477
H-Index105
YayıncıAmerican Veterinary Medical Association
ÜlkeUnited States
Veterinary (miscellaneous) (Q2)
Medicine (miscellaneous) (Q3)
Metrikler
29
Atıf
9
Yazar