Scopus
YÖKSİS Eşleşti
What is the effectiveness of surgical and non-surgical therapies in the treatment of ischemic priapism in patients with sickle cell disease? A systematic review by the EAU Sexual and Reproductive Health Guidelines Panel
International Journal of Impotence Research · Şubat 2024
YÖKSİS Kayıtları
What is the effectiveness of surgical and non-surgical therapies in the treatment of ischemic priapism in patients with sickle cell disease? A systematic review by the EAU Sexual and Reproductive Health Guidelines Panel
International Journal of Impotence Research · 2022 SCI-Expanded
DOÇENT MURAT GÜL →
Makale Bilgileri
DergiInternational Journal of Impotence Research
Yayın TarihiŞubat 2024
Cilt / Sayfa36 · 20-35
Scopus ID2-s2.0-85136803833
Özet
Sickle cell disease (SCD) is an inherited hemoglobin disorder characterized by the occlusion of small blood vessels by sickle-shaped red blood cells. SCD is associated with a number of complications, including ischemic priapism. While SCD accounts for at least one-third of all priapism cases, no definitive treatment strategy has been established to specifically treat patients with SC priapism. The aim of this systematic review was to assess the efficacy and safety of contemporary treatment modalities for acute and stuttering ischemic priapism associated with SCD. The primary outcome measures were defined as resolution of acute priapism (detumescence) and complete response of stuttering priapism, while the primary harm outcome was as sexual dysfunction. The protocol for the review has been registered (PROSPERO Nr: CRD42020182001), and a systematic search of Medline, Embase, and Cochrane controlled trials databases was performed. Three trials with 41 observational studies met the criteria for inclusion in this review. None of the trials assessed detumescence, as a primary outcome. All of the trials reported a complete response of stuttering priapism; however, the certainty of the evidence was low. It is clear that assessing the effectiveness of specific interventions for priapism in SCD, well-designed, adequately-powered, multicenter trials are strongly required.
Yazarlar (33)
1
Murat Gul
ORCID: 0000-0002-6657-6227
2
B. Luca
ORCID: 0000-0003-0040-784X
3
Konstantinos Dimitropoulos
4
Paolo Capogrosso
ORCID: 0000-0003-2347-9504
5
Uros Milenkovic
6
Andrea Cocci
ORCID: 0000-0003-0138-6294
7
R. Veeratterapillay
8
Georgios Hatzichristodoulou
ORCID: 0000-0002-3170-7362
9
Vaibhav Modgil
10
Giorgio Ivan Russo
ORCID: 0000-0003-4687-7353
11
Tharu Tharakan
12
Arif Kalkanlı
13
M. I. Omar
ORCID: 0000-0002-1597-3126
14
Carlo Bettocchi
ORCID: 0000-0002-1152-3005
15
Joana Carvalho
ORCID: 0000-0003-2362-0010
16
Giovanni Corona
ORCID: 0000-0002-9894-2885
17
T. H. Jones
18
Ates Kadioglu
ORCID: 0000-0002-4239-7638
19
J. I. Martinez-Salamanca
20
Ege Can Şerefoǧlu
21
Paolo Verze
22
Suks Minhas
23
Andrea Salonia
24
Carlo Bettochi
25
J. I.Martínez Salamanca
26
J. P.Pereira de Carvalho
27
H. Jones
28
Luca Boeri
ORCID: 0000-0003-0040-784X
29
Konstantinous Dimitropoulos
30
Marco Falcone
ORCID: 0000-0003-1101-892X
31
Afonso Morgado
32
Karen Czeloth
33
Michael Ager
Kurumlar
Aberdeen Royal Infirmary
Aberdeen United Kingdom
Azienda USL di Bologna
Bologna Italy
Biruni Üniversitesi
Istanbul Turkey
Centro Hospitalar Universitário de São João
Porto Portugal
Charing Cross Hospital
London United Kingdom
Chelsea and Westminster Hospital NHS Foundation Trust
London United Kingdom
Departement Ontwikkeling en Regeneratie
Leuven Belgium
Freeman Hospital
Newcastle United Kingdom
Hospital Universitario Puerta de Hierro Majadahonda
Majadahonda Spain
IRCCS Ospedale San Raffaele
Milan Italy
Istanbul Üniversitesi
Istanbul Turkey
Julius-Maximilians-Universität Würzburg
Wurzburg Germany
Lusófona University
Lisbon Portugal
Manchester Royal Infirmary
Manchester United Kingdom
Martha-Maria Hospital
Nurnberg Germany
Selçuk Üniversitesi
Selçuklu Turkey
Siloah St. Trudpert Klinikum
Pforzheim Germany
T. C. Sağlık Bakanlığı, Taksim Eğitim ve Araştirma Hastanesi
Istanbul Turkey
Technische Universität München
Munich Germany
The Sheffield Medical School
Sheffield United Kingdom
Università degli Studi dell'Insubria
Varese Italy
Università degli Studi di Catania
Catania Italy
Università degli Studi di Firenze
Florence Italy
Università degli Studi di Foggia
Foggia Italy
Università degli Studi di Napoli Federico II
Naples Italy
Università degli Studi di Torino
Turin Italy
Università Vita-Salute San Raffaele
Milan Italy
University of Aberdeen
Aberdeen United Kingdom
Urological Research Institute
Milan Italy
Metrikler
5
Atıf
33
Yazar