Scopus
YÖKSİS Eşleşti
Conservative and medical treatments of non-sickle cell disease-related ischemic priapism: a systematic review by the EAU Sexual and Reproductive Health Panel
International Journal of Impotence Research · Şubat 2024
YÖKSİS Kayıtları
Conservative and medical treatments of non-sickle cell disease-related ischemic priapism: a systematic review by the EAU Sexual and Reproductive Health Panel
International Journal of Impotence Research · 2022 SCI-Expanded
DOÇENT MURAT GÜL →
Makale Bilgileri
DergiInternational Journal of Impotence Research
Yayın TarihiŞubat 2024
Cilt / Sayfa36 · 6-19
Scopus ID2-s2.0-85136576130
Özet
Conservative and medical treatments are considered the first step in ischemic priapism (IP) management, although there is no clear evidence regarding their efficacy. We conducted a systematic review on behalf of the EAU Guidelines panel on Sexual and Reproductive health to analyse the available evidence on the efficacy and safety of conservative and medical treatment for non-sickle cell disease-related IP. Databases searched for relevant literature investigating efficacy and safety of conservative measures and medical treatment for IP included Medline, EMBASE, Cochrane Libraries and clinicaltrial.gov published up to September 2021. Overall, 41 retrospective, 3 prospective single-arm studies and 3 randomized controlled trials met the inclusion criteria. Intracavernous injection with sympathomimetic (ICIs) agents were the most frequently utilized treatment with efficacy ranging from 0 to 100% of cases. The combination of ICIs with corporeal aspiration with or without irrigation with saline was successful in 70 to 100% of cases. Oral treatment with β2 receptor agonist (e.g., terbutaline) showed mild to moderate efficacy. Conservative methods including ice pack, exercise, cold enema and ejaculation depicted lower effectiveness in resolving priapism (1–55%). Longer time interval from the onset to the resolution of IP was associated with higher rate of erectile dysfunction at follow-up (30–70%), especially after 24 h.
Yazarlar (21)
1
Paolo Capogrosso
ORCID: 0000-0003-2347-9504
2
Kostas Dimitropolous
3
Giorgio Ivan Russo
ORCID: 0000-0003-4687-7353
4
Tharu Tharakan
5
Uros Milenkovic
6
Andrea Cocci
ORCID: 0000-0003-0138-6294
7
Luca Boeri
ORCID: 0000-0003-0040-784X
8
Murat Gul
ORCID: 0000-0002-6657-6227
9
Carlo Bettocchi
ORCID: 0000-0002-1152-3005
10
Joana Carvalho
ORCID: 0000-0003-2362-0010
11
Arif Kalkanlı
12
Giovanni Corona
ORCID: 0000-0002-9894-2885
13
Georgios Hatzichristodoulou
ORCID: 0000-0002-3170-7362
14
H. Jones
15
Ates Kadioglu
ORCID: 0000-0002-4239-7638
16
J. I. Martinez-Salamanca
17
Vaibhav Modgil
18
Ege Can Şerefoǧlu
19
Paolo Verze
20
Andrea Salonia
21
Suks Minhas
Kurumlar
Aberdeen Royal Infirmary
Aberdeen United Kingdom
Azienda Ospedaliera Ospedale di Circolo e Fondazione Macchi di Varese
Varese Italy
Barnsley Hospital NHS Foundation Trust
Barnsley United Kingdom
Biruni Üniversitesi
Istanbul Turkey
Charing Cross Hospital
London United Kingdom
Dipartimento di Medicina, Chirurgia e Odontoiatria “Scuola Medica Salernitana"
Baronissi Italy
Hospital Universitario Puerta de Hierro Majadahonda
Majadahonda Spain
Imperial College Faculty of Medicine
London United Kingdom
IRCCS Ospedale San Raffaele
Milan Italy
İstanbul Tıp Fakültesi
Istanbul Turkey
KU Leuven– University Hospital Leuven
Leuven Belgium
Manchester Royal Infirmary
Manchester United Kingdom
Martha-Maria Hospital Nuremberg
Nurnberg Germany
Ospedale Bellaria
Bologna Italy
Selçuk Üniversitesi
Selçuklu Turkey
Taksim Training & Research Hospital
Instanbul Turkey
Universidade do Porto
Porto Portugal
Università degli Studi di Catania
Catania Italy
Università degli Studi di Firenze
Florence Italy
Università degli Studi di Foggia
Foggia Italy
Università degli Studi di Milano
Milan Italy
Università Vita-Salute San Raffaele
Milan Italy
University of Aberdeen
Aberdeen United Kingdom
Metrikler
5
Atıf
21
Yazar