Scopus
YÖKSİS Eşleşti
The Evaluation of the Relation Between Nasal Polyp Etiopathogenesis and the Amount of Biofilm
Genel Tip Dergisi · Şubat 2022
YÖKSİS Kayıtları
THE EVALUATION OF THE RELATION BETWEEN NASAL POLYP ETIOPATHOGENESIS AND THE AMOUNT OF BIOFILM
Genel Tıp Dergisi · 2022 TR DİZİN
PROFESÖR BÜLENT ULUSOY →
Makale Bilgileri
DergiGenel Tip Dergisi
Yayın TarihiŞubat 2022
Cilt / Sayfa32 · 36-38
Scopus ID2-s2.0-105009241308
Özet
Objective: To evaluate the effect of biofilm layer on polyp formation in nasal polyposis by comparing the amount of biofilm layer on polyp tissue and the normal mucosa. Materials and Methods: This study is a prospective study. 14 patients who underwent functional endoscopic sinus surgery (FESS) for nasal polyposis were evaluated. Patients were had no history of previous FESS. Tissue samples were obtained from lower turbinate (Group 1 n:14) and from nasal polyp (Group 2, n:14) of the same nasal cavity. Biofilm presence was identified using scanning electron microscopic (SEM) morphological findings. In biofilm positive samples, the presence of biofilm in less than 25% of the surface area was classified as (+), between 25-50% as (++), and over 50% as (+++). Results: In Group 2, with SEM imaging, (+++) biofilm presence was detected in 9 patients and (++) biofilm was detected in 5 patients. In Group 1, no biofilm was detected 8 patients, while; (+++), (++), and (+) biofilm presence was detected in 1, 2, and 3 patients respectively. Significant difference was found between group 1 and group 2 with respect to the amount of biofilm according to SEM (p =0.000). Conclusion: In samples, statistically significant difference was found between polyp tissue and normal mucosa in terms of the amount of biofilm. However, further studies with larger patient series are required in order to reach a definitive conclusion on the effect of biofilm on pathogenesis of polyp.
Yazarlar (7)
1
K. Bozdemir
2
Elif Ersoy Çallıoğlu
3
Bülent Ulusoy
ORCID: 0000-0001-7643-7100
4
Selami Candan
ORCID: 0000-0002-7402-1360
5
Serkan Serifler
ORCID: 0000-0003-0771-7373
6
Nurcan Ozyurt Koçakoğlu
ORCID: 0000-0001-7137-8631
7
Yuce İslamoğlu
ORCID: 0000-0002-1294-7088
Anahtar Kelimeler
Biofilm; Nasal Polyp; Microscopy
Electron
Scanning
Kurumlar
Ankara Bilkent City Hospital
Ankara Turkey
Ankara Yildirim Beyazit University
Ankara Turkey
Gazi Üniversitesi
Ankara Turkey
Selçuk Tip Fakültesi
Konya Turkey