Scopus
YÖKSİS Eşleşti
The clinical features, treatment approaches and outcomes of primary renal tumors in children
Genel Tip Dergisi · Aralık 2021
YÖKSİS Kayıtları
Çocuklarda primer böbrek tümörlerinin klinik özellikleri, tedavi yaklaşımları ve tedavi sonuçları
Genel Tıp Dergisi · 2021 TR DİZİN
DOÇENT BUKET KARA →
Çocuklarda primer böbrek tümörlerinin klinik özellikleri, tedavi yaklaşımları ve tedavi sonuçları
Genel Tıp Dergisi · 2021 TR DİZİN
PROFESÖR YAVUZ KÖKSAL →
Çocuklarda primer böbrek tümörlerinin klinik özellikleri, tedavi yaklaşımları ve tedavi sonuçları
Genel Tıp Dergisi · 2021 TR DİZİN
DOKTOR ÖĞRETİM ÜYESİ MEHMET SARIKAYA →
Makale Bilgileri
DergiGenel Tip Dergisi
Yayın TarihiAralık 2021
Cilt / Sayfa31 · 375-379
Scopus ID2-s2.0-105009244488
Özet
Objective: The aim of this study is to evaluate the clinical features, treatment approaches and outcomes of primary malign renal tumors in children. Material and Methods: The oncology charts of children diagnosed and followed up with primary malign renal tumors between 2006 and 2020 were retrospectively analyzed. Demographic and clinical characteristics, treatment approaches and follow-up of the patients were noted. Results: In this period, 49 of 950 children with malignant disease had primary renal kidney tumors (5.2%). The patients’ age ranged from three days to 13 years (median, 3 years). The male to female ratio was 25/24. The most common symptom and signs were abdominal mass. Both patients had bilateral disease (4.1%). Pathological diagnoses were Wilms tumor (n = 44, 89.8%), mesoblastic nephroma (n = 2, 4.1%), clear cell sarcoma of the kidney (n = 2, 4.1%), and primary synovial sarcoma of the kidney (n = 1, 2%). Only two of the patients with Wilms tumor had diffuse anaplasia. The risk groups of our patients were low (n=4, 8.3%), intermediate (n=35, 72.9%) and high risk (n=9, 18.8%). Follow-up periods ranged from two months to 15 years (median, 5 years). Overall and event free survival rates were 72.7% and 59.7%, respectively. Overall and event-free survival rates of Wilms tumor were 79% and 63%. Conclusion: Multidisciplinary approaches have increased success rates in primary malignant kidney tumors, especially in Wilms tumor. After that, it should be focused on both increasing the success of the treatment and reducing the treatment-related side effects.
Yazarlar (7)
1
Buket Kara
2
Mehmet Sarıkaya
ORCID: 0000-0003-2453-0893
3
Kubra Ertan
4
Nevzat Serdar Uğraş
5
Ilhan Çiftci
6
Güler Yavaş
7
Yavuz Koksal
Anahtar Kelimeler
Children
outcome
primary renal tumors
treatment approaches
Kurumlar
Selçuk Tip Fakültesi
Konya Turkey