Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
The Relationship Between Carpal Tunnel Syndrome and Cardiac Involvement in Patients with Mucopolysaccharidosis
Genel Tip Dergisi · Ekim 2024
YÖKSİS Kayıtları
The Relationship Between Carpal Tunnel Syndrome and Cardiac Involvement in Patients with Mucopolysaccharidosis
Genel Tıp Dergisi · 2024 TR DİZİN
Dr. Öğr. Üyesi BANU KADIOĞLU YILMAZ →
The Relationship Between Carpal Tunnel Syndrome and Cardiac Involvement in Patients with Mucopolysaccharidosis
Genel Tıp Dergisi · 2024 DOAJ: Directory of Open Access Journals
Doç. Dr. MELİH TİMUÇİN DOĞAN →
The Relationship Between Carpal Tunnel Syndrome and Cardiac Involvement in Patients with Mucopolysaccharidosis
Genel Tıp Dergisi · 2024 TR DİZİN
Prof. Dr. AHMET SERT →
Makale Bilgileri
Dergi
Genel Tip Dergisi
Yayın TarihiEkim 2024
Cilt / Sayfa34 · 733-739
Scopus ID2-s2.0-105009422614
Erişim🔓 Açık Erişim
Özet
Background/Aims: Mucopolysaccharidoses (MPSs) are a group of progressive multisystemic diseases, and it is unknown whether there is a relationship between these system involvements. In this study, we aimed to investigate whether there is a relationship between cardiac involvement and carpal tunnel syndrome (CTS) in MPS patients. Methods: The study was conducted as a cross-sectional study between May 12, 2023, and June 30, 2024. Patients between the ages of 2 and 20 years who were diagnosed with MPS Types I, II, IV A, and VI enzymatically and genetically and who underwent electromyography for CTS screening and transthoracic echocardiography for cardiac involvement were included in the study. Results: Twenty-six MPS patients were included in the study. The mean age of the patients was 128±58 months. There was cardiac involvement in 21 (80.8%) of the patients. Heart valve involvement was present in 20 (76.9%) patients. Our study found that 14 (53.8%) of our MPS patients had CTS. CTS was present in all patients in the MPS type I, II, and VI groups but not in any MPS type IV A patients. As a result of the statistical analysis, the presence of MPS Type IV A was statistically significantly higher in the group without CTS than in the group with CTS (p<0.001). The presence of cardiac involvement, combined involvement of the aortic and mitral valves, and the severity of heart valve involvement were found to be statistically significantly higher in the patient group with CTS than in the patient group without CTS (p=0.007, p=0.005, p=0.009, respectively). Conclusions: Our study found that CTS was more common in patients with cardiac involvement, especially heart valve involvement. It seems considerable to screen these patients for CTS.
Yazarlar (5)
1
Banu Kadıoğlu Yılmaz
2
Melih Timuçin Doǧan
ORCID: 0000-0003-3565-8606
3
Onur Bulut
4
Ahmet Sert
ORCID: 0000-0002-1607-7569
5
Hüseyim Yılmaz
ORCID: 0000-0002-9971-9669
Anahtar Kelimeler
Cardiac involvement
Carpal tunnel syndrome
Heart valve involvement
Mucopolysaccharidosis
Kurumlar
Selçuk Tip Fakültesi
Konya Turkey
University of Health Sciences
Istanbul Turkey