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Determination of Potential Drug-Drug Interactions in Patients Using Quinolone Group Antibiotics

Genel Tip Dergisi · Haziran 2024

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YÖKSİS Kayıtları
Determination of Potential Drug-Drug Interactions in Patients Using Quinolone Group Antibiotics
Genel Tıp Dergisi · 2024 TR DİZİN
DOKTOR ÖĞRETİM ÜYESİ HARUN KIZILAY →
Determination of Potential Drug-Drug Interactions in Patients Using Quinolone Group Antibiotics
Genel Tıp Dergisi · 2024 TR DİZİN
DOKTOR ÖĞRETİM ÜYESİ YEŞİM ŞERİFE BAYRAKTAR →
Determination of Potential Drug-Drug Interactions in Patients Using Quinolone Group Antibiotics
Genel Tıp Dergisi · 2024 TR DİZİN
PROFESÖR JALE BENGİ ÇELİK →
Determination of Potential Drug-Drug Interactions in Patients Using Quinolone Group Antibiotics
Genel Tıp Dergisi · 2024 TR DİZİN
DOKTOR ÖĞRETİM ÜYESİ ŞEYMA TETİK RAMA →
Determination of Potential Drug-Drug Interactions in Patients Using Quinolone Group Antibiotics
Genel Tıp Dergisi · 2024 TR DİZİN
DOKTOR ÖĞRETİM ÜYESİ CANSU GÖNCÜOĞLU →
Determination of Potential Drug-Drug Interactions in Patients Using Quinolone Group Antibiotics
Genel Tıp Dergisi · 2024 EBSCO, proquest,TRDizin
PROFESÖR NAZLIM AKTUĞ DEMİR →
Determination of Potential Drug-Drug Interactions in Patients Using Quinolone Group Antibiotics
Genel Tıp Dergisi · 2024 TR DİZİN
PROFESÖR ONUR URAL →
Determination of Potential Drug-Drug Interactions in Patients Using Quinolone Group Antibiotics
Genel Tıp Dergisi · 2024 EBSCO
PROFESÖR ŞUA SÜMER →
Determination of Potential Drug-Drug Interactions in Patients Using Quinolone Group Antibiotics
Genel Tıp Dergisi · 2024 TR DİZİN
DOKTOR ÖĞRETİM ÜYESİ CENGİZHAN CEYLAN →

Makale Bilgileri

DergiGenel Tip Dergisi
Yayın TarihiHaziran 2024
Cilt / Sayfa34 · 371-375
Özet Aim: The aim of the study was to determine the potential drug drug interactions of patients receiving inpatient treatment in the intensive care unit and infectious diseases ward and using quinolone group antibiotics by using different interaction software programs. Material and Methods: The prescriptions of 100 patients who received inpatient treatment in infectious diseases service and intensive care unit at Selçuk University Faculty of Medicine Hospital between January 2022 and December 2022 and who were treated with quinolone group antibiotics during treatment were analyzed retrospectively. Results: Of the patients included in the study, 62 were male and 38 were female. The mean age of men was 65.76 ± 16.22 years, while the mean age of women was 68.63 ± 16.29 years. While Medscape® detected a total of 1776 interactions, this number was 1432 in Lexicomp® and 1693 in Drugs®.While 0.33% of the interactions detected in the Medscape® software program were contraindicated, 3.77% of the interactions were contraindicated in Lexicomp®. Kendall W coefficient 0.94, Chi-Square test 281.12, p <0.001 were found to be statistically significant. The software programs used to detect pDDIs are highly compatible with each other. Conclusion: High agreement was found between software programs used to detect potential drug-drug interactions. Interaction classifications between software programs are different. Therefore, clinicians may benefit from different software programs.

Yazarlar (12)

1
Cengizhan Ceylan
ORCID: 0000-0003-4164-9212
2
Erdenay Erden
ORCID: 0009-0003-9494-014X
3
Cansu Goncuoglu
4
Harun Kızılay
ORCID: 0000-0003-3660-0721
5
Seyma Tetik Rama
6
Yesim Serife Bayraktar
ORCID: 0000-0001-5156-7064
7
Jale Çelik
8
Görkem Yılmazer
ORCID: 0009-0005-3448-9638
9
Hatice Esranur Kiratlı
10
Nazlım Aktuğ Demir
11
Şua Sümer
12
Onur Ural

Anahtar Kelimeler

Antibiotics Drug interactions Quinolone Software

Kurumlar

Selçuk Tip Fakültesi
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey