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Assessing the Diagnostic Value of the Red Blood Cell Distribution-To-Platelet Ratio in Acute Leg Embolism Requiring Emergent Surgical Intervention

Genel Tip Dergisi · Ekim 2023

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YÖKSİS Kayıtları
Assessing the Diagnostic Value of the Red Blood Cell Distribution-To-Platelet Ratio in Acute Leg Embolism Requiring Emergent Surgical Intervention
Genel Tıp Dergisi · 2023 TR DİZİN
DOÇENT ÖMER FARUK ÇİÇEK →

Makale Bilgileri

DergiGenel Tip Dergisi
Yayın TarihiEkim 2023
Cilt / Sayfa33 · 608-613
Özet Background: The objective of this study was to evaluate the significance of the red blood cell distribution-to-platelet ratio (RPR) as a diagnostic indicator, derived from the initial hemogram measurements of patients who underwent emergent surgical treatment for acute leg embolism, by comparing it to a control group of healthy individuals. Methods: The study included 48 patients who underwent femoral embolectomy for acute lower limb ischemia, while an additional 49 individuals were enrolled as a control group. Demographic, clinical, and laboratory data were compared between the two groups. Using the receiver operating characteristic curve to determine the RPR cutoff value, the area under the curve, sensitivity, and specificity were calculated. Results: The age and gender distribution of both groups were comparable. The admission RPR values of patients who underwent surgery for acute embolism were statistically higher compared to healthy individuals (0.0677 (IQR: 0.0547-0.0803) vs. 0.0504 (IQR: 0.0441-0.0572), p<0.001). The area under the curve for acute extremity embolism was determined as 0.832, and the RPR cut-off value of 0.566 was found to predict acute extremity embolism with a sensitivity of 72.9% and a specificity of 73.5% (p<0.001). Conclusion: Our findings provide preliminary evidence that RPR can be used as a novel diagnostic indicator for acute leg embolism. Rather than being used diagnostically alone, it is thought that a comprehensive evaluation of this ratio, when combined with the patient’s medical history and other clinical findings, has the potential to expedite the diagnostic process, particularly in healthcare settings with limited access to imaging resources.

Yazarlar (12)

1
Ömer Faruk Çiçek
ORCID: 0000-0002-4675-3273
2
Ataberk Atalay
ORCID: 0009-0001-9904-0509
3
Recep Çelik
ORCID: 0009-0008-2038-3009
4
Mehmet Özdil
ORCID: 0009-0003-4791-9516
5
Fatih Boncuk
ORCID: 0009-0009-7960-0554
6
Adeviye Ünlü
ORCID: 0009-0005-1708-9675
7
Nisa Nur Babadağ
ORCID: 0009-0000-4010-2309
8
Şükran Aybike Ayyildiz
ORCID: 0009-0004-8241-8837
9
Farid Salehi
ORCID: 0009-0001-6730-6157
10
Emre Coşkuner
ORCID: 0009-0009-1086-8069
11
Elif Yildirim
ORCID: 0009-0004-1912-1125
12
Zülal Ceylan
ORCID: 0009-0003-8739-8620

Anahtar Kelimeler

acute leg ischemia hemogram platelet red blood cell distribution

Kurumlar

Selçuk Tip Fakültesi
Konya Turkey