Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q3
Tobacco induces abnormal metabolism of tryptophan via the kynurenine pathway
Turkish Journal of Biochemistry · Şubat 2025
YÖKSİS Kayıtları
Tobacco induces abnormal metabolism of tryptophan via the kynurenine pathway
Turkish Journal of Biochemistry · 2025 SCI-Expanded
Prof. Dr. ALİ ÜNLÜ →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Asymmetric dimethylarginine and arginine levels in patients with rheumatoid arthritis
2013 ISSN: 0250-4685 SCI-Expanded
Prof. Dr. ALİ ÜNLÜ →
Asymmetric dimethylarginine and arginine levels in patients with rheumatoid arthritis
2013 ISSN: 0250-4685 SCI-Expanded 3 atıf
Prof. Dr. ALİ ÜNLÜ →
Asymmetric dimethylarginine levels in Behçet s Disease
2014 ISSN: 0250-4685 SCI-Expanded
Prof. Dr. BAHADIR ÖZTÜRK →
Asymmetric dimethylarginine levels in Behçet s Disease
2014 ISSN: 0250-4685 SCI-Expanded
Prof. Dr. HÜSAMETTİN VATANSEV →
Asymmetric dimethylarginine and arginine levels in patients with rheumatoid arthritis
2013 ISSN: 0250-4685 SCI-Expanded 3 atıf
Prof. Dr. HÜSAMETTİN VATANSEV →
Asymmetric dimethylarginine and arginine levels in patients with rheumatoid arthritis
2013 ISSN: 0250-4685 SCI-Expanded
Prof. Dr. ABDULLAH SİVRİKAYA →
Is median value of Double Screening Test regional?
2015 ISSN: 0250-4685 SCI-Expanded Q4
Doç. Dr. RAMAZAN KOCABAŞ →
Calculation of measurement uncertainty of biochemical parameters
2015 ISSN: 02504685 SCI-Expanded
Prof. Dr. SEDAT ABUŞOĞLU →
The effects of grape seed extract against toxicity of benzene on liver and kidney tissues of albino mice biochemical evaluation
2015 ISSN: 0250-4685 SCI-Expanded
Prof. Dr. ERTAN ORUÇ →
Analysis of trace elements in epileptic patients
2015 ISSN: 0250-4685 SCI-Expanded
Prof. Dr. BAHADIR ÖZTÜRK →
Serum Paraoxonase Levels and Oxidative Stress in Patients with Scleroderma
2015 ISSN: 0250-4685 SCI-Expanded
Prof. Dr. HÜSAMETTİN VATANSEV →
Analysis of Trace Elements in Epileptic Patients
2015 ISSN: 0250-4685 SCI-Expanded
Prof. Dr. HÜSAMETTİN VATANSEV →
The Analytical Performance of The C Petide and Insuline Test
2015 ISSN: 0250-4685 SCI-Expanded
Prof. Dr. HÜSAMETTİN VATANSEV →
Procalcitonin Levels in Inflammatory Disease
2015 ISSN: 0250-4685 SCI-Expanded
Prof. Dr. HÜSAMETTİN VATANSEV →
Comparison of Routine Biochemical and Hormonal Values of Sleeve Gastrectomy Applied Patients
2015 ISSN: 0250-4685 SCI-Expanded
Prof. Dr. HÜSAMETTİN VATANSEV →
Comparison Of MPV WBC and Neutrophil Lymphocyte Ratio of Sleeve Gastrectomy Applied Patients
2015 ISSN: 0250-4685 SCI-Expanded
Prof. Dr. HÜSEYİN YILMAZ →
Influence of Pinealectomy on Hemogram Parameters of Rats Applied to Sepsis Model
2015 ISSN: 0250-4685 SCI-Expanded
Prof. Dr. HÜSAMETTİN VATANSEV →
Meme Kanser Hücrelerinin Fluıdıgm Dynamıc Array Kullanılarak Kantitatif miRNA Ekspresyaon Analizi
2015 ISSN: 0250-4685 SCI-Expanded
Prof. Dr. ALİ ÜNLÜ →
25 OH D3 ve 1 25 OH 2 D3 ün MCF 7 Meme Kanser Hücre Hattının Proliferasyonu Üzerine Kıyaslanması
2015 ISSN: 0250-4685 SCI-Expanded
Prof. Dr. ALİ ÜNLÜ →
The effect of single dose administration of nandrolone decanoate on plasma irisin adropin leptin levelsTek doz nandrolon dekonat uygulamasının plazma irisin adropin leptin düzeylerine etkisi
2015 ISSN: 0250-4685 SCI-Expanded
Prof. Dr. SEYFULLAH HALİLOĞLU →
Makale Bilgileri
ISSN02504685
Yayın TarihiŞubat 2025
Cilt / Sayfa50 · 152-159
Scopus ID2-s2.0-105001652270
Erişim🔓 Açık Erişim
Özet
Objectives: This study aims to investigate the effect of smoking on the metabolism of kynurenine and thus contribute to the elucidation of the potential mechanism of cigarette smoking. Methods: The study included 82 smokers and 63 nonsmokers who applied to the Family Medicine Polyclinic for routine check-ups. Sociodemographic data, routine laboratory results, Framingham risk scores (FRS), and Fagerström Nicotine Dependence Test (FTND) were recorded. Serum tryptophan, kynurenine, kynurenic acid, 3-hydroxyanthranilic acid, 3-hydroxykynurenine, and quinolinic acid concentrations were measured with tandem mass spectrometry. Results: Serum tryptophan levels (p=0.040) were statistically significantly lower in smokers, and the kynurenine/tryptophan ratio and serum kynurenine, kynurenic acid, quinolinic acid, 3-hydroxyanthranilic acid levels were higher (p<0.001). The correlation analysis in the smoker group showed a positive correlation between serum kynurenic acid levels and FTDN. The serum kynurenine levels were positively correlated with the levels of total cholesterol, triglyceride, low-density lipoprotein cholesterol, and FRS. There was a positive correlation between serum quinolinic acid levels and participants' systolic and diastolic blood pressures. Conclusions: Our findings showed that tryptophan metabolism via the kynurenine pathway was induced in smokers.
Yazarlar (6)
1
Mustafa Onmaz
2
Duygu Eryavuz Onmaz
ORCID: 0000-0001-8564-1824
3
Nur Demirbaş
ORCID: 0000-0002-4038-9386
4
Ruhuşen Kutlu
5
Ali Ünlü
ORCID: 0000-0002-9991-3939
6
Ahmet Emre Hatir
ORCID: 0000-0001-8094-3444
Anahtar Kelimeler
kynurenine
oxidative stress
smoking
tobacco
tryptophan
Kurumlar
Bandırma Onyedi Eylül University
Bandirma Turkey
Fetih Family Health Center
Konya Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Tip Fakültesi
Konya Turkey
Ululrmak Family Health Center
Konya Turkey
Scimago Dergi (ISSN Eşleşmesi)
Turkish Journal of Biochemistry
Q3
OA
SJR Skoru0,232
H-Index26
YayıncıWalter de Gruyter GmbH
ÜlkeGermany
Biochemistry (medical) (Q3)
Biochemistry (Q4)
Clinical Biochemistry (Q4)
Molecular Biology (Q4)
Metrikler
3
Atıf
6
Yazar
5
Anahtar Kelime