Scopus
YÖKSİS Eşleşti
Determination of the effect of Tarantula cubensis alcoholic extract on cadmium embryotoxicity
Veterinary Research Forum · Nisan 2025
YÖKSİS Kayıtları
Determination of the effect of Tarantula cubensis alcoholic extract on cadmium embryotoxicity
Veterinary Research Forum · 2025 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ HARUN KIZILAY →
Makale Bilgileri
DergiVeterinary Research Forum
Yayın TarihiNisan 2025
Cilt / Sayfa16 · 203-208
Scopus ID2-s2.0-105003405389
Özet
Tarantula cubensis alcoholic extract (TCAE) is a homeopathic product used in the veterinary field. This study aimed to determine the effects of TCAE on cadmium (Cd) toxicity in the embryo. The study used 220 fertile, incubated chicken eggs divided into 11 equal groups on the 7<sup>th</sup> day of incubation. The groups comprised untreated and physiological saline control groups, a group with TCAE alone, four groups with varying doses of Cd alone and four groups with the same doses of Cd plus TCAE. At the end of the incubation period, the eggs were opened, kidney and liver tissue samples were taken for histopathology and the number of dead and living embryos were recorded. In the prsent study, the median lethal dose of Cd was determined to be 0.029 mg per egg and the median lethal dose of Cd plus TCAE was determined to be 0.020 mg per egg. The histopathological examinations determined that kidney and liver damage were increased when TCAE and Cd were administered together, that was higher than when Cd was given alone. Thus, TCAE, which had no toxic effect on the embryo when used alone, might increase the embryotoxic activity of Cd. However, more detailed studies are needed.
Yazarlar (5)
1
Rahmi Canbar
ORCID: 0000-0001-7100-4437
2
G. Akcakavak
3
Muhittin Uslu
ORCID: 0000-0002-9027-4229
4
Mustafa Sedat Arslan
ORCID: 0000-0002-4079-500X
5
Harun Kızılay
ORCID: 0000-0003-3660-0721
Anahtar Kelimeler
Cadmium
Embryotoxic
in ovo methods
Tarantula cubensis alcoholic extract
Kurumlar
Aksaray Üniversitesi
Aksaray Turkey
Bozok Üniversitesi
Yozgat Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Üniversitesi
Selçuklu Turkey