Scopus
YÖKSİS Eşleşti
Enzyme Inhibitory and Antioxidant Potential with Phytochemical Analysis of Satureja hasturkii H.Duman & Dirmenci: A New Record From Türkiye
Chemistry and Biodiversity · Ocak 2025
YÖKSİS Kayıtları
Enzyme Inhibitory and Antioxidant Potential with Phytochemical Analysis of Satureja hasturkii H.Duman & Dirmenci: A New Record From Türkiye
Chemistry&Biodiversity · 2025 SCI-Expanded
ARAŞTIRMA GÖREVLİSİ TUĞSEN BÜYÜKYILDIRIM →
Makale Bilgileri
DergiChemistry and Biodiversity
Yayın TarihiOcak 2025
Scopus ID2-s2.0-105005550276
Özet
The genus Satureja (Lamiaceae) includes many aromatic species with known antimicrobial, antioxidant, anti-inflammatory, and anticancer properties. Satureja hasturkii H.Duman & Dirmenci is a newly described species from Türkiye (2023), and its biological potential has not been explored yet. In this study, dichloromethane (DCM), ethyl acetate (EtOAc), and ethanol (EtOH) extracts were assessed for their enzyme inhibitory activity against acetylcholinesterase (AChE), butyrylcholinesterase (BChE), elastase, collagenase, tyrosinase (TYR), and xanthine oxidase (XO), along with their antioxidant activities using DPPH, nitric oxide (NO), metal-chelation, ferric-reducing antioxidant power (FRAP), and cupric-reducing antioxidant capacity (CUPRAC) assays. The extracts showed low to moderate inhibition levels at 2 mg/mL (stock concentration). The EtOAc extract showed the most effective elastase (16.70 ± 2.08%) and collagenase (13.96 ± 3.70%) inhibition. XO inhibition was highest with EtOH (34.34 ± 0.60%), followed by EtOAc extract (30.32 ± 2.03%). DCM extract displayed the strongest metal-chelating activity (72.38 ± 1.86%). Essential oil composition analyzed by GC-MS revealed docosane, γ-terpinene, and p-cymene as major constituents. HPLC analysis of the extracts identified rosmarinic acid and luteolin-7-O-glucoside as abundant phenolics. These results highlight the species’ potential as a natural source of bioactive agents for pharmaceutical and nutraceutical applications.
Yazarlar (8)
1
Tugsen Buyukyildirim
2
Fahriye Ocal Ozdamar
3
Gokcen Baysal Furtana
4
Hasya Nazli Gok
5
Temel Özek
6
Ilkay Erdogan Orhan
7
F. Sezer Senol
8
Hayri Duman
Anahtar Kelimeler
antioxidant activity
enzyme inhibition
GC/MS
HPLC
Satureja hasturkii
Kurumlar
Anadolu Üniversitesi
Eskisehir Turkey
Gazi Üniversitesi
Ankara Turkey
Lokman Hekim Üniversitesi
Ankara Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Turkish Academy of Sciences (TÜBA)
Ankara Turkey