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Reticulated platelets and coronary slow flow: a study in stable coronary artery disease

Turkish Journal of Biochemistry · Nisan 2024

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YÖKSİS Kayıtları
Reticulated platelets and coronary slow flow: a study in stable coronary artery disease
Turkish Journal of Biochemistry · 2024 SCI-Expanded
Dr. Öğr. Üyesi HÜSEYİN TEZCAN →

Makale Bilgileri

Dergi Turkish Journal of Biochemistry
Yayın TarihiNisan 2024
Cilt / Sayfa49 · 283-288
Erişim🔓 Açık Erişim
Özet Objectives: The coronary slow flow (CSF) phenomenon remains a clinical enigma, characterized by delayed opacification of coronary vessels despite angiographically normal or nearly normal arteries. This cross-sectional study explores the potential relationship between reticulated platelets (RPs) and CSF in stable coronary artery disease patients. Methods: A total of 200 participants, meeting specific inclusion and exclusion criteria, underwent coronary angiography. Reticulated platelet levels were measured using Sysmex series hematology analyzers. Demographic data, laboratory parameters, and coronary flow velocities were assessed. Results: The study comprised 100 individuals with CSF and 100 with normal coronary anatomy. The CSF group exhibited higher rates of diabetes (35 vs. 22 %, p=0.017) and smoking (62 vs. 45 %, p=0.021). Reticulated platelet rates were elevated in the CSF group. However, statistical significance was not reached (p=0.105). Conclusions: This study provides insights into the interplay between reticulated platelets and the CSF phenomenon in stable coronary artery disease. Although reticulated platelet levels did not emerge as a major predictor for CSF in this stable phase, the findings contribute to ongoing efforts to understand the multifaceted mechanisms underlying CSF.

Yazarlar (4)

1
S. S. Erdem
2
Hüseyin Tezcan
3
Hasan Basri Yıldırım
ORCID: 0000-0002-5104-8907
4
Zafer Buyukterzi

Anahtar Kelimeler

coronary angiography coronary slow flow microvascular dysfunction platelet turnover reticulated platelets

Kurumlar

Konya City Hospital
Konya Turkey