Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Measurement of serum creatinine levels with liquid chromatography-tandem mass spectrometry: Comparison with Jaffe and enzymatic methods
Turkish Journal of Biochemistry · Haziran 2021
YÖKSİS Kayıtları
Measurement of serum creatinine levels with liquid chromatography-tandem mass spectrometry: comparison with Jaffe and enzymatic methods
Turkish Journal of Biochemistry · 2020 SCI-Expanded
DOÇENT GÜLSÜM ABUŞOĞLU →
Measurement of serum creatinine levels with liquid chromatography-tandem mass spectrometry: comparison with Jaffe and enzymatic methods
Turkish Journal of Biochemistry · 2020 SCI-Expanded
PROFESÖR ALİ ÜNLÜ →
Measurement of serum creatinine levels with liquid chromatography-tandem mass spectrometry: comparison with Jaffe and enzymatic methods
Turkish Journal of Biochemistry-Turk Biyokimya Dergisi · 2021 SCI-Expanded
PROFESÖR ABDULLAH SİVRİKAYA →
Measurement of serum creatinine levels with liquid chromatography-tandem mass spectrometry: comparison with Jaffe and enzymatic methods
Turkish Journal of Biochemistry · 2021 SCI-Expanded
PROFESÖR SEDAT ABUŞOĞLU →
Measurement of serum creatinine levels with liquid chromatography-tandem mass spectrometry: comparison with Jaffe and enzymatic methods
Turkish Journal of Biochemistry · 2021 SCI-Expanded
PROFESÖR ALİ ÜNLÜ →
Makale Bilgileri
DergiTurkish Journal of Biochemistry
Yayın TarihiHaziran 2021
Cilt / Sayfa46 · 263-271
Scopus ID2-s2.0-85109677258
Erişim🔓 Açık Erişim
Özet
Objectives: Our aim was to validate a mass spectrometric creatinine method and compare this method with Jaffe and enzymatic serum creatinine methods. Methods: 90 samples were included. The levels were classified into three groups according to serum creatinine results as Group 1: Lower (n=30) (0.16-0.59 mg/dL), Group 2: Normal (n=30) (0.62-1.18 mg/dL) and Group 3: Higher (n=30) (1.33-3.88 mg/dL). Jaffe and enzymatic creatinine measurements were performed on the Beckman Coulter AU5800 autoanalyzer. Results: Serum creatinine was linear from 0.039 up to 10 mg/dL, CV and bias values were ranged between 1.9-3.8% and 2-15%. Correlation coefficients were 0.990 (95% confidence interval 0.984-0.993), 0.992 (95% confidence interval 0.988-0.995) and 0.994 (95% confidence interval 0.991-0.996) for LC-MS/MS-Enzymatic, LC-MS/ MS-Jaffe and Enzymatic-Jaffe, respectively. Conclusions: Although, Jaffe method for serum creatinine measurement is still much more practical and cheap, so in use for routine practice, tandem mass spectrometric detection of serum creatinine can be used as an accurate and specific method for verification of discordant clinical results, existence of possible interferences and serum levels under 0.5 mg/dL creatinine results such as pediatric or pregnant populations.
Yazarlar (7)
1
Mehmet Yildirimel
2
Mehmet Nuri Atalar
3
Sedat Abusoglu
ORCID: 0000-0002-2984-0527
4
Duygu Eryavuz Onmaz
ORCID: 0000-0001-8564-1824
5
Abdullah Sivrikaya
6
Gulsum Abusoglu
7
Ali Ünlü
ORCID: 0000-0002-9991-3939
Anahtar Kelimeler
Comparison
Creatinine
Enzymatic
Jaffe
LC-MS/MS
Kurumlar
Iğdır Üniversitesi
Igdir Turkey
Selçuk Tip Fakültesi
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
7
Atıf
7
Yazar
5
Anahtar Kelime