Scopus
YÖKSİS Eşleşti
Partial protective effects of melatonin on cadmium-induced changes in hematological characteristics in rats
Biotechnic and Histochemistry · Ocak 2022
YÖKSİS Kayıtları
Partial protective effects of melatonin on cadmium-induced changes in hematological characteristics in rats
Biotechnic & Histochemistry · 2022 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ İLKNUR ÜNDAĞ →
Makale Bilgileri
DergiBiotechnic and Histochemistry
Yayın TarihiOcak 2022
Cilt / Sayfa97 · 192-198
Scopus ID2-s2.0-85105993241
Özet
We investigated the effects of melatonin (Mlt) on hematological characteristics to determine the percentage of alpha-naphthyl acetate esterase (ANAE) positive lymphocytes in rats chronically exposed to cadmium (Cd). We used four groups of male rats: control (C), melatonin (Mlt), cadmium (Cd) and Cd + Mlt (CdMlt). Blood samples were obtained to assess the erythrocytes (RBC), leukocytes (WBC), platelets (PLT), hemoglobin (HGB), hematocrit (HCT), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular volume (MCV) as well as alpha-naphthyl acetate esterase (ANAE) positive lymphocytes. We found that the number of WBC increased in the Cd group compared to the other three experimental groups. Low MCV and MCHC values caused by Cd were ameliorated by Mlt treatment in the CdMlt group. We found no significant change in the RBC, HGB, MCH, PLT and HCT values among the experimental groups. Mlt treatment also increased the percentage of ANAE positive lymphocytes. Mlt partially protects some hematological characteristics in cases of chronic Cd toxicity.
Yazarlar (3)
1
Ihsan Kisadere
ORCID: 0000-0003-0732-0464
2
M. Faruk Aydin
3
Ündag
Anahtar Kelimeler
Alpha-naphthyl acetate esterase
cadmium
hematology
melatonin
rats
toxicity
Kurumlar
Balikesir Üniversitesi
Balikesir Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
6
Atıf
3
Yazar
6
Anahtar Kelime