Scopus
YÖKSİS DOI Eşleşti
SJR Q1
Protective Effect of N-Acetylcysteine Against Aluminum-Induced Kidney Tissue Damage in Rats
Biological Trace Element Research · Nisan 2023
YÖKSİS Kayıtları
Protective Effect of N-Acetylcysteine Against Aluminum-Induced Kidney Tissue Damage in Rats
Biological Trace Element Research · 2023 SCI-Expanded
Prof. Dr. MURAT BOYDAK →
Protective Effect of N-Acetylcysteine Against Aluminum-Induced Kidney Tissue Damage in Rats
BIOLOGICAL TRACE ELEMENT RESEARCH · 2023 SCI
Prof. Dr. HASAN HÜSEYİN DÖNMEZ →
Protective effect of Nacetylcysteine against aluminum-induced kidney tissue damage in rats
Biological Trace Element Research · 2023 SCI-Expanded
Prof. Dr. HASAN HÜSEYİN DÖNMEZ →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Investigation of the Relationship Between Serum Trace Elements and MSFC Levels in Multiple Sclerosis: A Cross-sectional Case-Control Study
2025 ISSN: 0163-4984 SCI
Dr. Öğr. Üyesi CİHAT ÖZGÜNCÜ →
Effects of Zinc Deficiency and Supplementation on Malondialdehyde and Glutathione Levels in Blood and Tissues of Rats Performing Swimming Exercise
2003 ISSN: 0163-4984 SCI-Expanded
Prof. Dr. ABDULLAH SİVRİKAYA →
Effect of Selenium Supplementation on Lipid Peroxidation Antioxidant Enzymes and Lactate Levels in Rats Immediately After Acute Swimming Exercise
2011 ISSN: 0163-4984 SCI-Expanded
Prof. Dr. ABDULLAH SİVRİKAYA →
Effects of dietary cadmium and boron supplementation on performance eggshell quality and mineral concentrations of bone in laying hens
2015 ISSN: 0163-4984 SCI-Expanded
Prof. Dr. OSMAN OLGUN →
Serum and Cerebrospinal Fluid Magnesium Levels Glasgow Coma Scores and In Hospital Mortality in Patients with Acute Stroke
2009 ISSN: 0163-4984 SCI
Prof. Dr. HASAN KARA →
Magnesium Sulfate in Emergency Department Patients with Hypertension
2009 ISSN: 0163-4984 SCI
Prof. Dr. HASAN KARA →
Levels of Selenium Zinc Copper and Cardiac Troponin I in Serum of Patients with Acute Coronary Syndrome
2013 ISSN: 0163-4984 SSCI
Prof. Dr. HASAN KARA →
Elements in Sera of Elite Taekwondo Athletes Effects of Vitamin E Supplementation
2011 ISSN: 0163-4984 SCI 3 atıf
Prof. Dr. EKREM BOYALI →
The Effect of Vitamin A Supplementation on Various Elements in Elite Taekwondo Players
2011 ISSN: 0163-4984 SCI 2 atıf
Prof. Dr. EKREM BOYALI →
Effects of Exercise and Zinc Supplementation on Cytokine Release in Young Wrestlers
2011 ISSN: 0163-4984 SCI-Expanded
Prof. Dr. MEHMET KILIÇ →
Effect of Intraperitoneal Selenium Administration on Liver Glycogen Levels in Rats Subjected to Acute Forced Swimming
2011 ISSN: 0163-4984 SSCI
Prof. Dr. MEHMET KILIÇ →
Effects of Acute Swimming Exercise on Some Elements in Rats
2009 ISSN: 0163-4984 SCI-Expanded
Prof. Dr. MEHMET KILIÇ →
Effect of Zinc Supplementation on Antioxidant Activity in Young Wrestlers
2010 ISSN: 0163-4984 SCI-Expanded
Prof. Dr. MEHMET KILIÇ →
Effects of Chronic Fluorosis on Electrocardiogram in Sheep
2003 ISSN: 0163-4984 SCI-Expanded 24 atıf
Prof. Dr. NURCAN DÖNMEZ →
Effect of Zinc Supplementation on Antioxidant Activity in Young Wrestlers
2010 ISSN: 0163-4984 SCI-Expanded 10 atıf
Prof. Dr. RASİM MOĞULKOÇ →
Testosterone Levels in Athletes at Rest and Exhaustion Effects of Calcium Supplementation
2009 ISSN: 0163-4984 SCI-Expanded 3 atıf
Prof. Dr. RASİM MOĞULKOÇ →
Effects of Magnesium Supplementation on Testosterone Levels of Athletes and Sedentary Subjects at Rest and after Exhaustion
2011 ISSN: 0163-4984 SCI-Expanded 6 atıf
Prof. Dr. RASİM MOĞULKOÇ →
Effects of zinc deficiency and supplementation on malondialdehyde and glutathione levels in blood and tissue of rats performing swimming exercise
2003 ISSN: 0163-4984 SCI-Expanded 18 atıf
Prof. Dr. ABDULKERİM KASIM BALTACI →
Effects of exercise and zinc supplementation on cytokine release in young wrestlers
2011 ISSN: 0163-4984 SSCI 4 atıf
Prof. Dr. RASİM MOĞULKOÇ →
Effects of zinc supplementation on the element distribution in kidney tissue of diabetic rats subjected to acute swimming
2012 ISSN: 0163-4984 SSCI 5 atıf
Prof. Dr. RASİM MOĞULKOÇ →
Makale Bilgileri
ISSN01634984
Yayın TarihiNisan 2023
Cilt / Sayfa201 · 1806-1815
Scopus ID2-s2.0-85129811174
Özet
Aluminum (AL) is an important nephrotoxic agent with a high daily exposure rate and property of accumulation in tissues. This study aimed to investigate the potential protective efficacy of N-acetylcysteine (NAC) against AL exposure-induced nephrotoxicity in rats. Twenty-eight rats were randomly divided into 4 groups as control, N-acetylcysteine group (NC), AL, and AL + NC, with an equal number of rats in each group (n = 7). No application was made to the control group. A total of 150 mg/kg/day NAC was administered to the NC group and 30 mg/kg/day AL was administered to the AL group intraperitoneally (i.p.). The AL + NC group received 30 mg/kg/day AL and 150 mg/kg/day NAC i.p. Biochemical parameters in blood serum and histopathological changes in kidney tissue, oxidative stress parameters, spexin (SPX), and apoptotic protein levels were examined after 15 days. Histopathological changes, biochemical parameters, oxidative stress parameters, and apoptotic protein levels were significantly irregular in the AL group compared to the control group. Moreover, SPX levels increased in the AL group. However, NAC treatment regulated AL exposure-related changes in the AL + NC group. NAC treatment may have a prophylactic effect against nephrotoxicity due to AL exposure. SPX may play a role in AL-induced nephrotoxicity.
Yazarlar (4)
1
Sercan Kaya
ORCID: 0000-0001-9014-2448
2
Tuba Yalçın
ORCID: 0000-0002-2359-9832
3
M. Boydak
4
Hasan Hüseyin Dönmez
Anahtar Kelimeler
Aluminum
N-acetylcysteine
Nephrotoxicity
Neuropeptide Q
Spexin
Kurumlar
Batman University
Batman Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Biological Trace Element Research
Q1
OA
SJR Skoru0,890
H-Index119
YayıncıSpringer
ÜlkeUnited States
Inorganic Chemistry (Q1)
Biochemistry (Q2)
Biochemistry (medical) (Q2)
Clinical Biochemistry (Q2)
Endocrinology, Diabetes and Metabolism (Q2)
Medicine (miscellaneous) (Q2)
Metrikler
24
Atıf
4
Yazar
5
Anahtar Kelime