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Clinical and laboratory characteristics of COVID-19 cases followed in selçuk university faculty of medicine

Klimik Dergisi · Ocak 2020

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YÖKSİS Kayıtları
Clinical and Laboratory Characteristics of COVID-19 Cases Followed in Selçuk University Faculty of Medicine
Klimik Dergisi/Klimik Journal · 2020 E-SCI
PROFESÖR NAZLIM AKTUĞ DEMİR →
Clinical and Laboratory Characteristics of COVID-19 Cases Followed in Selçuk University Faculty of Medicine
Klimik Dergisi/Klimik Journal · 2020 E-SCI
PROFESÖR HATİCE TÜRK DAĞI →
Clinical and Laboratory Characteristics of COVID-19 Cases Followed in Selçuk University Faculty of Medicine
Klimik Dergisi/Klimik Journal · 2020 E-SCI
PROFESÖR ONUR URAL →

Makale Bilgileri

DergiKlimik Dergisi
Yayın TarihiOcak 2020
Cilt / Sayfa33 · 122-127
Erişim🔓 Açık Erişim
Özet Objective: Understanding the natural course of COVID-19 and determining its clinical findings are essential for early diagnosis and treatment. In this study, we aimed to investigate clinical and laboratory characteristics of cases followed with a diagnosis of COVID-19 in Selçuk University Faculty of Medicine Department of Infectious Diseases and Clinical Microbiology. Methods: Among patients followed with a diagnosis of pos-sible/definitive COVID-19, those with a positive SARS-CoV-2 RT-PCR test were evaluated retrospectively in terms of their clin-ical, laboratory and thorax computed tomography (CT) data. Results: Among 407 patients followed with a diagnosis of pos-sible/definitive COVID-19, 149 (36.6%) were SARS-CoV-2 RT-PCR test-positive. 82 (55%) of the patients were female and 67 (45%) were male. Mean age was 49.3±7.6 years. 11 (7.4%) were health care workers. While the most common symptom was cough with 46.3%, fever was observed in 29.5%, sore throat in 27.5% and malaise in 26.8% of the patients. 94 (63.1%) of the patients had underlying diseases. Hypertension and diabetes mellitus were the most common underlying disease. Laboratory findings were leukopenia in 12 (8.1%), lymphopenia in 34 (22.8%), throm-bocytopenia in 24 (16.1%), elevated D-dimer levels in 43 (28.9%), elevated lactate dehydrogenase levels in 73 (49%), and elevated C-reactive protein (CRP) levels in 45 (30.2%) patients. While 71 (47.6%) of the patients had normal thorax CT, 43 (28.9%) had mild pneumonia, and 35 (23.5%) moderate pneumonia. D-dimer and CRP levels were higher in those with pneumonia than those without pneumonia (p=0.001 and p=0.001, respectively). As the pneumonia level increased, the increase of D-dimer and CRP levels became evident (p=0.003 and p=0.001, respectively). Conclusions: The clinical course of COVID-19 patients varies. It is noteworthy that there is a positive correlation between the severity of pneumonia and the increase in D-dimer and CRP levels in COVID-19. Klimik Dergisi. 2020; 33(2): 122-7.

Yazarlar (8)

1
Şua Sümer
2
Onur Ural
3
Nazlım Aktuğ Demir
4
Şeyma Çifci
ORCID: 0000-0001-8174-4797
5
Burcu Türkseven
ORCID: 0000-0001-5692-4972
6
Abidin Kılınçer
7
Hatice Türk Dağı
8
Lütfi Saltuk Demir

Anahtar Kelimeler

Clinical findings COVID-19 Di-agnosis Pandemics SARS-CoV-2

Kurumlar

Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

6
Atıf
8
Yazar
5
Anahtar Kelime

Sistemimizdeki Yazarlar