Scopus
YÖKSİS Eşleşti
The plasma galectin-3 level has high specificity and sensitivity for predicting postoperative atrial fibrillation after coronary artery bypass surgery
European Review for Medical and Pharmacological Sciences · Ocak 2022
YÖKSİS Kayıtları
The plasma galectin-3 level has high specificity and sensitivity for predicting postoperative atrial fibrillation after coronary artery bypass surgery
Eur Rev Med Pharmacol Sci . · 2022 SCI-Expanded
DOÇENT KENAN ERDEM →
The plasma galectin-3 level has high specificity and sensitivity for predicting postoperative atrial fibrillation after coronary artery bypass surgery
European Review for Medical and Pharmacological Sciences · 2022 SCI
PROFESÖR MEHMET ALKILIÇ HORASANI ÖÇ →
The plasma galectin-3 level has high specificity
and sensitivity for predicting postoperative atrial
fibrillation after coronary artery bypass surgery
European Review for Medical and Pharmacological Sciences · 2022 SCI-Expanded
PROFESÖR ALİ ÜNLÜ →
The plasma galectin-3 level has high specificity and sensitivity for predicting postoperative atrial fibrillation after coronary artery bypass surgery
European Review for Medical and Pharmacological Sciences · 2022 SCI
PROFESÖR BAHAR ÖÇ →
The plasma galectin-3 level has high specificity and sensitivity for predicting postoperative atrial fibrillation after coronary artery bypass surgery
European Review for Medical and Pharmacological Sciences · 2022 SCI
PROFESÖR ALİ ÜNLÜ →
The plasma galectin-3 level has high specificity and sensitivity for predicting postoperative atrial fibrillation after coronary artery bypass surgery
European Review for Medical and Pharmacological Sciences · 2022 SCI
PROFESÖR ALİ ÜNLÜ →
The plasma galectin-3 level has high specificity and sensitivity for predicting postoperative atrial fibrillation after coronary artery bypass surgery
Eur Rev Med Pharmacol Sci . · 2022 SCI-Expanded
PROFESÖR ALİ ÜNLÜ →
Makale Bilgileri
DergiEuropean Review for Medical and Pharmacological Sciences
Yayın TarihiOcak 2022
Cilt / Sayfa26 · 9072-9078
Scopus ID2-s2.0-85145345626
Özet
OBJECTIVE: Postoperative new-onset atrial fibrillation (POAF) commonly occurs after coronary artery bypass graft (CABG) surgery. This study aimed to determine the utility of the preoperative netrin-1 and galectin-3 levels for predicting POAF following CABG surgery, as well as that of postoperative serial measurement for assessing these markers’ patterns of expression. PATIENTS AND METHODS: This prospective cohort study included 50 patients that underwent CABG surgery. The plasma netrin-1 and galectin-3 levels were measured via enzyme-linked immunosorbent assay (ELISA) before surgery (baseline) and at 6, 12, and 24 h after surgery. The patients were divided into two groups according to the occurrence of POAF; the POAF (+) group and the POAF (–) group. RESULTS: In total, 26 patients developed POAF, whereas 24 remained in sinus rhythm. Baseline galectin-3 levels were higher in the POAF (+) group than in the POAF (–) group (30.7 ± 10.1 pg mL-1 and 15.7 ± 3.6 pg mL–1, respectively). The post-CABG surgery galectin-3 level increased in both the POAF (+) and POAF (–) groups at 6 h (46.2 ± 26.3 pg mL-1 and 24.9 ± 5.9 pg mL-1, respectively), 12 h (45.2 ± 24.1 pg mL-1 and 26.6 ± 9.3 pg mL-1, respectively), and 24 h (54.2 ± 33.5 pg mL-1and 28.6 ± 7.7 pg mL-1, respectively). The plasma netrin-1 level did not differ between groups at baseline or at 6, 12, and 24 h post CABG surgery. CONCLUSIONS: Whereas netrin-1 does not appear to have any utility as a marker for the development of POAF in CABG surgery patients, the plasma galectin-3 level has high specificity and sensitivity for predicting POAF following CABG surgery and could be considered a marker for predicting POAF.
Yazarlar (7)
1
Kenan Erdem
2
Ertuğrul Kurtoglu
ORCID: 0000-0001-5835-087X
3
Mehmet Oc
ORCID: 0000-0002-7832-3067
4
Bahar Oc
ORCID: 0000-0002-2253-5191
5
T. F. Ilgenli
6
Ali Ünlü
ORCID: 0000-0002-9991-3939
7
Tevfik Eryavuz Onmaz
ORCID: 0000-0003-3113-0548
Anahtar Kelimeler
Coronary artery bypass graft
Galectin-3
Netrin-1
Postoperative atrial fibrillation
Kurumlar
Malatya Turgut Ozal University
Malatya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
5
Atıf
7
Yazar
4
Anahtar Kelime