Scopus
YÖKSİS Eşleşti
Risk factors for diabetes mellitus in women with primary ovarian insufficiency
Biological Trace Element Research · Eylül 2013
YÖKSİS Kayıtları
Risk Factors for Diabetes Mellitus in Women with Primary Ovarian Insufficiency
Biological Trace Element Research · 2013 SCI-Expanded
PROFESÖR SÜLEYMAN BALDANE →
Makale Bilgileri
DergiBiological Trace Element Research
Yayın TarihiEylül 2013
Cilt / Sayfa154 · 313-320
Scopus ID2-s2.0-84882670263
Özet
Primary ovarian insufficiency (POI) is not only a gynecological problem but also has serious effects on women's health such as changes in hormone levels that can trigger fluctuations in blood sugar level and inflammation status. The present study was designed to determine vitamin D, copper, zinc, metabolic parameters [insulin, homeostasis model of assessment-insulin resistance (HOMA-IR)], inflammation parameters such as procalcitonin and high sensitivity C reactive protein (hs-CRP), and lipid profile in POI patients and control subjects with normal menstrual cycles. A total of 43 patients with nondiabetic POI were studied in order to evaluate and compare the findings with those of the control group, which comprised 33 women with normal menstrual cycles. The women with POI had higher levels of serum copper, serum insulin, glucose, LDL-cholesterol, total cholesterol, HOMA-IR, hs-CRP, and procalcitonin, whereas serum vitamin D and zinc levels were lower compared with the healthy control group. Follicle-stimulating hormone (FSH) levels were positively correlated with insulin, glucose, HOMA-IR, hs-CRP, procalcitonin, and copper and negatively correlated with vitamin D and zinc levels. In multivariate statistic analyses with body mass index and FSH as dependent variables, FSH was positively associated with copper and HOMA-IR negatively with vitamin D levels. The present study demonstrated that women with POI have traditional risk factors for diabetes mellitus, including lower levels of vitamin D, whereas higher levels of copper and HOMA-IR. © 2013 Springer Science+Business Media New York.
Yazarlar (8)
1
Mustafa Kulaksızoğlu
ORCID: 0000-0001-9908-7449
2
Suleyman Hilmi Ipekci
ORCID: 0000-0003-4410-2212
3
Levent Kebapcilar
4
Ayşe Gül Kebapçilar
5
Huseyin Korkmaz
6
Fikret Akyürek
7
Süleyman Baldane
8
Mustafa Sait Gonen
Anahtar Kelimeler
Copper
HOMA-IR
hs-CRP
Insulin
POI
Procalcitonin
Zinc
Kurumlar
Beyhekim State Hospital
Konya Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
30
Atıf
8
Yazar
7
Anahtar Kelime