Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Mean platelet volume could be a possible biomarker for papillary thyroid carcinomas
Asian Pacific Journal of Cancer Prevention · Ocak 2015
YÖKSİS Kayıtları
Mean Platelet Volume Could be a Possible Biomarker for Papillary Thyroid Carcinomas
Asian Pacific Journal of Cancer Prevention · 2015 SCOPUS, PUBMED, INDEX COPERNICUS, EMBASE
PROFESÖR SÜLEYMAN BALDANE →
Makale Bilgileri
DergiAsian Pacific Journal of Cancer Prevention
Yayın TarihiOcak 2015
Cilt / Sayfa16 · 2671-2674
Scopus ID2-s2.0-84928630190
Erişim🔓 Açık Erişim
Özet
Thyroid cancer is the most prevalent endocrine cancer and is evident in nearly 5% of thyroid nodules. The correlation between mean platelet volume (MPV) and many other cancer types has been investigated previously. However, the correlation between papillary thyroid carcinoma (PTC) and MPV has not yet been studied in detail. The aim of this study was to examine whether MPV would be a useful inflammatory marker to differentiate PTC patients from cases of benign goiter and healthy controls. Preoperative MPV levels in patients with PTC were found to be significantly higher when compared with benign goiter patients and healthy controls ((respectively, 8.05 femtoliter (fl), 7.57 fl, 7.36 fl, p=0.001). After surgical treatment of PTC patients, a significant decrease in MPV levels was seen (8.05 fl versus 7.60 fl, p=0.005). ROC analysis suggested 7.81 as the cut-off value for MPV (AUC=0.729, sensitivity 60%, specificity 80%). In conclusion, maybe changes in MPV levels can be used as an easily available biomarker for monitoring the risk of PTC in patients with thyroid nodules, enabling early diagnosis of PTC.
Yazarlar (4)
1
Süleyman Baldane
2
Suleyman Hilmi Ipekci
ORCID: 0000-0003-4410-2212
3
Mehmet Sözen
ORCID: 0000-0002-8428-1115
4
Levent Kebapcilar
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
44
Atıf
4
Yazar