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Prorenin and secreted frizzled-related protein 4 levels in women with gestational diabetes mellitus

Bratislava Medical Journal · Ocak 2018

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YÖKSİS Kayıtları
Prorenin and secreted frizzled-related protein 4 levels in women with gestational diabetes mellitus
Bratislava Medical Journal-Bratislavske Lekarske Listy · 2018 SCI-Expanded
PROFESÖR SÜLEYMAN BALDANE →
Prorenin and secreted frizzled-related protein 4 levels in women with gestational diabetes mellitus
Bratislava Medical Journal-Bratislavske Lekarske Listy · 2018 SCI-Expanded
PROFESÖR ALİ ÜNLÜ →
Prorenin and secreted frizzled-related protein 4 levels in women with gestational diabetes mellitus
Bratislava Medical Journal · 2018 Endekste taranmıyor
PROFESÖR ALİ ÜNLÜ →
Prorenin and secreted frizzled-related protein 4 levels in women with gestational diabetes mellitus
Bratislava Medical Journal · 2018 SCI-Expanded
PROFESÖR ALİ ÜNLÜ →
Prorenin and secreted frizzled-related protein 4 levels in women with gestational diabetes mellitus
Bratislava Medical Journal-Bratislavske Lekarske Listy · 2018 SCI-Expanded
PROFESÖR SEDAT ABUŞOĞLU →

Makale Bilgileri

DergiBratislava Medical Journal
Yayın TarihiOcak 2018
Cilt / Sayfa119 · 450-453
Erişim🔓 Açık Erişim
Özet OBJECTIVE: This study was designed to investigate prorenin and secreted frizzled-related protein 4 (SFRP4) levels in pregnancies with or without gestational diabetes mellitus (GDM). METHODS: A total of 76 pregnant women were included in the study. Thirty-five of the pregnant women were included in GDM group according to the results of oral glucose tolerance tests (OGTT) and 41 of them were included in the control group. RESULTS: In the group with GDM, SFRP4 value was found to be significantly higher than that of the control group (5.59 ± 3.32 ng/mL vs 4.05 ± 2.15 ng/mL; p = 0.017). Women with GDM had significantly higher serum prorenin levels compared with control group [737 (427-1339) pg/mL vs. 535 (376-725) pg/mL; p = 0.009]. There was a significant positive association between prorenin and SFRP4 levels in GDM (r = 0.91; p < 0.001) and control groups (r = 0.42; p = 0.002) and whole pregnancies (r = 0.75; p = 0.002). CONCLUSION: We have shown that prorenin and SFRP4 were significantly elevated in GDM patients when compared to healthy control group. Furthermore, we found that there was a positive correlation between prorenin and SFRP4.

Yazarlar (7)

1
Süleyman Baldane
2
Suleyman Hilmi Ipekci
ORCID: 0000-0003-4410-2212
3
Ayşe Gül Kebapçilar
4
A. Abusoglu
5
H. Beyhekim
6
Tolgay Tuyan İlhan
7
Ali Ünlü
ORCID: 0000-0002-9991-3939

Anahtar Kelimeler

Gestational diabetes mellitus Prorenin SFRP 4 Subclinical inflammation

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

12
Atıf
7
Yazar
4
Anahtar Kelime

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